Search Results - "Yamada, Satoru"
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Efficacy and safety of low and very low carbohydrate diets for type 2 diabetes remission: systematic review and meta-analysis of published and unpublished randomized trial data
Published in BMJ (Online) (13-01-2021)“…To determine the efficacy and safety of low carbohydrate diets (LCDs) and very low carbohydrate diets (VLCDs) for people with type 2 diabetes. Systematic…”
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Epigenetics in susceptibility, progression, and diagnosis of periodontitis
Published in The Japanese dental science review (01-11-2022)“…Periodontitis is characterized by irreversible destruction of periodontal tissue. At present, the accepted etiology of periodontitis is based on a three-factor…”
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Paradigm Shifts in Nutrition Therapy for Type 2 Diabetes
Published in Keio journal of medicine (26-09-2017)“…Currently, the low-energy diet is the only recognized nutrition therapy for type 2 diabetes in Japan. However, in recent decades, many foreign scientific…”
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Mechanical regulation of macrophage function - cyclic tensile force inhibits NLRP3 inflammasome-dependent IL-1β secretion in murine macrophages
Published in Inflammation and Regeneration (07-02-2019)“…Mechanical stress maintains tissue homeostasis by regulating many cellular functions including cell proliferation, differentiation, and inflammation and immune…”
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Mice lacking PLAP-1/asporin counteracts high fat diet-induced metabolic disorder and alveolar bone loss by controlling adipose tissue expansion
Published in Scientific reports (02-03-2021)“…Adipose tissue fibrosis with chronic inflammation is a hallmark of obesity-related metabolic disorders, and the role of proteoglycans in developing adipose…”
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Cyclic Stretch Force Induces Periodontal Ligament Cells to Secrete Exosomes That Suppress IL-1β Production Through the Inhibition of the NF-κB Signaling Pathway in Macrophages
Published in Frontiers in immunology (20-06-2019)“…In the oral mechanical environment, periodontal ligament cells (PDL cells) contribute to maintaining periodontal tissue homeostasis. Recent studies showed that…”
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Paradigm Shifts in Nutrition Therapy for Type 2 Diabetes: Nutrition Therapy for Diabetes
Published in Keio journal of medicine (2017)“…Currently, the low-energy diet is the only recognized nutrition therapy for type 2 diabetes in Japan. However, in recent decades, many foreign scientific…”
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Inhibition of the CXCL9-CXCR3 axis suppresses the progression of experimental apical periodontitis by blocking macrophage migration and activation
Published in Scientific reports (28-01-2021)“…Apical periodontitis (AP) is an acute or chronic inflammatory disease caused by complex interactions between infected root canal and host immune system. It…”
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Porphyromonas gingivalis induces entero-hepatic metabolic derangements with alteration of gut microbiota in a type 2 diabetes mouse model
Published in Scientific reports (15-09-2021)“…Periodontal infection induces systemic inflammation; therefore, aggravating diabetes. Orally administered periodontal pathogens may directly alter the gut…”
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Anti-CD44 antibody treatment lowers hyperglycemia and improves insulin resistance, adipose inflammation, and hepatic steatosis in diet-induced obese mice
Published in Diabetes (New York, N.Y.) (01-03-2015)“…Type 2 diabetes (T2D) is a metabolic disease affecting >370 million people worldwide. It is characterized by obesity-induced insulin resistance, and growing…”
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Periodontal Regeneration by Allogeneic Transplantation of Adipose Tissue Derived Multi-Lineage Progenitor Stem Cells in vivo
Published in Scientific reports (29-01-2019)“…The ultimate goal of periodontal disease treatment is the reorganization of functional tissue that can regenerate lost periodontal tissue. Regeneration of…”
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Expression of asporin reprograms cancer cells to acquire resistance to oxidative stress
Published in Cancer science (01-03-2021)“…Asporin (ASPN), a small leucine‐rich proteoglycan expressed predominantly by cancer associated fibroblasts (CAFs), plays a pivotal role in tumor progression…”
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A Non-calorie-restricted Low-carbohydrate Diet is Effective as an Alternative Therapy for Patients with Type 2 Diabetes
Published in Internal Medicine (2014)“…Objective Although caloric restriction is a widely used intervention to reduce body weight and insulin resistance, many patients are unable to comply with such…”
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Public RNA-seq data-based identification and functional analyses reveal that MXRA5 retains proliferative and migratory abilities of dental pulp stem cells
Published in Scientific reports (20-09-2023)“…Dental pulp stem cells (DPSC) usually remain quiescent in the dental pulp tissue; however, once the dental pulp tissue is injured, DPSCs potently proliferate…”
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Cu2ZnSnS4-type thin film solar cells using abundant materials
Published in Thin solid films (31-05-2007)Get full text
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Mice Lacking PLAP-1/Asporin Show Alteration of Periodontal Ligament Structures and Acceleration of Bone Loss in Periodontitis
Published in International journal of molecular sciences (01-11-2023)“…Periodontal ligament-associated protein 1 (PLAP-1), also known as Asporin, is an extracellular matrix protein expressed in the periodontal ligament and plays a…”
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Fibroblast growth factor‐2 inhibits CD40‐mediated periodontal inflammation
Published in Journal of cellular physiology (01-05-2019)“…Fibroblast growth factor‐2 (FGF‐2) stimulates periodontal regeneration by a broad spectrum of effects on periodontal ligament (PDL) cells, such as…”
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Plap-1 lineage tracing and single-cell transcriptomics reveal cellular dynamics in the periodontal ligament
Published in Development (Cambridge) (01-10-2022)“…Periodontal tissue supports teeth in the alveolar bone socket via fibrous attachment of the periodontal ligament (PDL). The PDL contains periodontal…”
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Pharmacological Activation of YAP/TAZ by Targeting LATS1/2 Enhances Periodontal Tissue Regeneration in a Murine Model
Published in International journal of molecular sciences (04-01-2023)“…Due to their multi-differentiation potential, periodontal ligament fibroblasts (PDLF) play pivotal roles in periodontal tissue regeneration in vivo. Several in…”
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PPARγ-Induced Global H3K27 Acetylation Maintains Osteo/Cementogenic Abilities of Periodontal Ligament Fibroblasts
Published in International journal of molecular sciences (11-08-2021)“…The periodontal ligament is a soft connective tissue embedded between the alveolar bone and cementum, the surface hard tissue of teeth. Periodontal ligament…”
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