Search Results - "Yamada, Hiromi"

Potent and specific antitumor effect of CEA‐targeted photoimmunotherapy by Shirasu, Naoto, Yamada, Hiromi, Shibaguchi, Hirotomo, Kuroki, Motomu, Kuroki, Masahide

“…Conventional photodynamic therapy (PDT) for cancer is limited by the insufficient efficacy and specificity of photosensitizers. We herein describe a highly…”
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Siwi cooperates with Par-1 kinase to resolve the autoinhibitory effect of Papi for Siwi-piRISC biogenesis by Yamada, Hiromi, Nishida, Kazumichi M., Iwasaki, Yuka W., Isota, Yosuke, Negishi, Lumi, Siomi, Mikiko C.

“…Bombyx Papi acts as a scaffold for Siwi-piRISC biogenesis on the mitochondrial surface. Papi binds first to Siwi via the Tudor domain and subsequently to piRNA…”
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Hierarchical roles of mitochondrial Papi and Zucchini in Bombyx germline piRNA biogenesis by Nishida, Kazumichi M., Sakakibara, Kazuhiro, Iwasaki, Yuka W., Yamada, Hiromi, Murakami, Ryo, Murota, Yukiko, Kawamura, Takeshi, Kodama, Tatsuhiko, Siomi, Haruhiko, Siomi, Mikiko C.

“…The biogenesis of piRNAs in the silkworm Bombyx is simpler than in Drosophila , with the exonucleases Trim and Nbr having no major role, and the endonuclease…”
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Protocol: Prospective observational study aiming for micro-elimination of hepatitis C virus in Nagawa town: The Nagawa Project by Kobayashi, Hiroyuki, Joshita, Satoru, Akahane, Yuki, Matsuzaki, Katsuhiko, Yamada, Hiromi, Aomura, Daiki, Joshita, Nao, Midorikawa, Hajime, Suyama, Kazuhiro, Ota, Masao, Wakabayashi, Shun-Ichi, Yamashita, Yuki, Sugiura, Ayumi, Yamazaki, Tomoo, Misawa, Hiromichi, Umemura, Takeji

“…The World Health Organization has set a goal of hepatitis C virus (HCV) elimination by the year 2030. However, no regions in Japan have succeeded in…”
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Highly versatile cancer photoimmunotherapy using photosensitizer-conjugated avidin and biotin-conjugated targeting antibodies by Shirasu, Naoto, Shibaguchi, Hirotomo, Yamada, Hiromi, Kuroki, Masahide, Yasunaga, Shin'ichiro

“…Photoimmunotherapy (PIT) employing antibody-photosensitizer conjugates is a promising treatment for cancer. However, the fixed antigen specificity severely…”
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Isolation of three main sericin components from the cocoon of the silkworm, Bombyx mori by Takasu, Y. (National Inst. of Agrobiological Sciences, Tsukuba, Ibaraki (Japan)), Yamada, H, Tsubouchi, K

“…To characterize the sericin components of the cocoon of silkworm Bombyx mori, fresh cocoon shells were dissolved in saturated aqueous lithium thiocyanate…”
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Sericin enhances attachment of cultured human skin fibroblasts by Tsubouchi, K. (National Inst. of Agrobiological Sciences, Tsukuba, Ibaraki (Japan)), Igarashi, Y, Takasu, Y, Yamada, H

“…Human skin fibroblasts were cultured on sericin prepared from cocoon shells. The living cell number alter 72h was enhanced to 250% of the no-sericin control…”
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Transplantation of mature adipocyte-derived dedifferentiated fat cells promotes locomotor functional recovery by remyelination and glial scar reduction after spinal cord injury in mice by Yamada, Hiromi, Ito, Daisuke, Oki, Yoshinao, Kitagawa, Masato, Matsumoto, Taro, Watari, Tosihiro, Kano, Koichiro

“…•DFAT promoted locomotor functional recovery after SCI in mice.•DFAT-promoted remyelination positively correlates with functional recovery.•DFAT-induced…”
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Multidirectional analysis for a colchicine poisoning case revealed detail cause of death and its mechanism by Okuda, Katsuhiro, Isozaki, Shotaro, Asari, Masaru, Tanaka, Hiroki, Horioka, Kie, Takahashi, Yuta, Hoshina, Chisato, Yamada, Hiromi, Mori, Kanae, Namba, Ryo, Shiono, Hiroshi, Ogawa, Katsuhiro, Shimizu, Keiko

“…•Tissue distribution of colchicine in humans died of acute colchicine poisoning.•Genetic analysis of stomach contents to reveal ingestion of Meadow…”
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Sonodynamic therapy of cancer using a novel porphyrin derivative, DCPH‐P‐Na(I), which is devoid of photosensitivity by Hachimine, Ken, Shibaguchi, Hirotomo, Kuroki, Motomu, Yamada, Hiromi, Kinugasa, Tetsushi, Nakae, Yoshinori, Asano, Ryuji, Sakata, Isao, Yamashita, Yuichi, Shirakusa, Takayuki, Kuroki, Masahide

“…To improve the efficacy of sonodynamic therapy of cancer using photosensitizers, we developed a novel porphyrin derivative designated DCPH‐P‐Na(I) and…”
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Molecular hierarchy of heparin-binding EGF-like growth factor-regulated angiogenesis in triple-negative breast cancer by Yotsumoto, Fusanori, Tokunaga, Eriko, Oki, Eiji, Maehara, Yoshihiko, Yamada, Hiromi, Nakajima, Kyoko, Nam, Sung Ouk, Miyata, Kohei, Koyanagi, Midori, Doi, Keiko, Shirasawa, Senji, Kuroki, Masahide, Miyamoto, Shingo

“…Heparin-binding EGF-like growth factor (HB-EGF) is one of several proangiogenic factors and represents a possible therapeutic target for patients with…”
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Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Thiosulfate in Human Blood and Urine as an Indicator of Hydrogen Sulfide Poisoning by Maseda, Chikatoshi, Hayakawa, Akira, Okuda, Katsuhiro, Asari, Masaru, Tanaka, Hiroki, Yamada, Hiromi, Jin, Shigeki, Horioka, Kie, Matoba, Kotaro, Shiono, Hiroshi, Matsubara, Kazuo, Shimizu, Keiko

“…Highlights • Quantitative determination method for thiosulfate by LC-MS/MS was developed. • Thiosulfate can be utilized for an index of hydrogen sulfide…”
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Ventilation measures to control aerosol transmission based on COVID‐19 outbreaks in hospitals in Japan by Hayashi, Motoya, Honma, Yoshinori, Kikuta, Koki, Hasegawa, Asako, Murata, Sayaka, Yamada, Hiromi, Ogata, Masayuki, Kagi, Naoki, Yanagi, U, Yamanaka, Toshio, Kim, Hoon, Kobayashi, Kenichi, Kaihara, Noriko, Ito, Akira, Shinohara, Fumihiko, Morimoto, Shoichi

“…COVID‐19 outbreaks occurred in several hospitals, and the National Institute of Infectious Diseases, local authorities, and universities carried out…”
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Measures against COVID‐19 concerning Summer Indoor Environment in Japan by Hayashi, Motoya, Yanagi, U, Azuma, Kenichi, Kagi, Naoki, Ogata, Masayuki, Morimoto, Shoichi, Hayama, Hirofumi, Mori, Taro, Kikuta, Koki, Tanabe, Shin‐ichi, Kurabuchi, Takashi, Yamada, Hiromi, Kobayashi, Kenichi, Kim, Hoon, Kaihara, Noriko

“…Information on air‐conditioning and ventilation has been continuously disseminated in response to the Japanese Government's announcement of the need for…”
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Identification and characterization of a novel sericin gene expressed in the anterior middle silk gland of the silkworm Bombyx mori by Takasu, Yoko, Yamada, Hiromi, Tamura, Toshiki, Sezutsu, Hideki, Mita, Kazuei, Tsubouchi, Kozo

“…Sericin is a group of proteins expressed in the middle silk gland that covers the surface of fibroin in the cocoon filament of Bombyx mori. Sericin consists of…”
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An objective approach using three indexes for determining fatal hypothermia due to cold exposure; statistical analysis of oxyhemoglobin saturation data by Yajima, Daisuke, Asari, Masaru, Okuda, Katsuhiro, Maseda, Chikatoshi, Yamada, Hiromi, Ichimaru, Chisato, Matsubara, Kazuo, Shiono, Hiroshi, Iwase, Hirotaro, Makino, Yosuke, Shimizu, Keiko

“…Graphical abstract Scatter plots of hypothermia (●) and control (□) cases, with L-O2 Hb (oxyhemoglobin (O2 -Hb) saturation levels in left heart blood) and L–R…”
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A Modified Adenovirus Vector–Mediated Antibody Screening Method Identifies EphA2 as a Cancer Target by Tanaka, Toshihiro, Yamada, Hiromi, Kuroki, Masahide, Kodama, Shohta, Tamura, Kazuo, Takamatsu, Yasushi

“…Abstract BACKGROUND: We constructed a genetically modified adenovirus vector incorporating an IgG Fc-binding motif from staphylococcal protein A, Z33…”
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Compositional changes of human hair melanin resulting from bleach treatment investigated by nanoscale secondary ion mass spectrometry by Kojima, Toru, Yamada, Hiromi, Isobe, Mitsuru, Yamamoto, Toshihiko, Takeuchi, Miyuki, Aoki, Dan, Matsushita, Yasuyuki, Fukushima, Kazuhiko

“…It is important to understand the influence of bleach treatment on human hair because it is one of the most important chemical treatments in hair cosmetic…”
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Clinical Performance Evaluation of a High-Risk Human Papillomavirus Genotyping Test "Clinichip HPV" Using Cervical Scrape Specimens by Yamada, Hiromi, Tabe, Yoko, Ishii, Kiyoshi, Terao, Yasuhisa, Yamashita, Yohei, Horii, Takashi, Takeda, Satoru, Ohsaka, Akimichi

“…Persistent infection with high-risk human papillomavirus (HPV) is closely associated with cervical cancer development. In this study, the performance of the…”
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In vivo application of an RNAi strategy for the selective suppression of a mutant allele by Kubodera, Takayuki, Yamada, Hiromi, Anzai, Masayuki, Ohira, Shinga, Yokota, Shigefumi, Hirai, Yukihiko, Mochizuki, Hideki, Shimada, Takashi, Mitani, Tasuku, Mizusawa, Hidehiro, Yokota, Takanori

“…Gene therapy for dominantly inherited diseases with small interfering RNA (siRNA) requires mutant allele-specific suppression when genes in which mutation…”
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