Wavefront Analysis and Contrast Sensitivity of Aspheric and Spherical Intraocular Lenses: A Randomized Prospective Study

To compare visual performance, total and high order wavefront aberrations (coma, spherical aberration, and other terms), and contrast sensitivity in 120 eyes implanted with one monofocal aspheric intraocular lens (IOL) and two spherical IOLs. Randomized prospective study. Sixty patients were randomi...

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Bibliographic Details
Published in:	American journal of ophthalmology Vol. 142; no. 5; pp. 750 - 756.e3
Main Authors:	Rocha, Karolinne Maia, Soriano, Eduardo S., Chalita, Maria Regina, Yamada, Ana Carolina, Bottós, Kátia, Bottós, Juliana, Morimoto, Lisangela, Nosé, Walton
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Inc 01-11-2006 Elsevier Elsevier Limited
Subjects:	Aged Aged, 80 and over Astigmatism Biological and medical sciences Cataracts Colleges & universities Coma Contrast Sensitivity - physiology Corneal Topography Diabetic retinopathy Female Glare Humans Lens Implantation, Intraocular Lenses, Intraocular Light Male Medical sciences Middle Aged Miscellaneous Ophthalmology Optics Patients Phacoemulsification Prospective Studies Pseudophakia - physiopathology Pupil - physiology Statistical analysis Surgery Surgical outcomes Variance analysis Visual Acuity - physiology Prospective Randomization Sensitivity Treatment Surgery Analysis Ophthalmology Intraocular lens Contrast Wavefront
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Summary:	To compare visual performance, total and high order wavefront aberrations (coma, spherical aberration, and other terms), and contrast sensitivity in 120 eyes implanted with one monofocal aspheric intraocular lens (IOL) and two spherical IOLs. Randomized prospective study. Sixty patients were randomized to receive three IOL types: Alcon AcrySofIQ (40 eyes), AcrySofNatural (40 eyes), and advanced medical optic (AMO)Sensar (40 eyes). Complete ophthalmologic examination including uncorrected visual acuity (UCVA), best-spectacle corrected visual acuity (BSCVA), corneal topography, and wavefront analysis were performed preoperatively, 30 days, and 90 days postoperatively. Pelli-Robson chart test and functional acuity contrast testing (FACT-Optec6500) were performed approximately 50 days after surgery. Statistical analyses were performed using analysis χ 2, analysis of variance (ANOVA), and multiple comparisons Tukey test. After 90 days, all eyes had postoperative BSCVA ≥20/32. The AcrySofIQ IOL showed statistically significant less induction of spherical aberration ( P < .001) when compared with the AMOSensar and the AcrySofNatural IOLs. The AMOSensar presented significantly less spherical aberration then the AcrySofNatural ( P < .05). The AcrySofIQ also had lower values of total and high-order aberration (HOA) ( P < .05) when compared with the AMOSensar and the AcrySofNatural. The mean values of trefoil 9, coma, and HOA root mean square (RMS) decreased between one and three months ( P < .001, P < .001, P = .023, P < .001, respectively) in all groups. Mean Pelli-Robson contrast sensitivity values in photopic condition were similar between the groups. The AcrySofIQ showed better results in 3cpd spatial frequency in mesopic condition using FACT-Optec 6500 ( P = .008), although there were no statistical differences in photopic and mesopic with glare conditions.
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ISSN:	0002-9394 1879-1891
DOI:	10.1016/j.ajo.2006.06.031