Search Results - "Yallowitz, Alisha R"
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Discovery of a periosteal stem cell mediating intramembranous bone formation
Published in Nature (London) (01-10-2018)“…Bone consists of separate inner endosteal and outer periosteal compartments, each with distinct contributions to bone physiology and each maintaining separate…”
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Bone controls browning of white adipose tissue and protects from diet-induced obesity through Schnurri-3-regulated SLIT2 secretion
Published in Nature communications (06-08-2024)“…The skeleton has been suggested to function as an endocrine organ controlling whole organism energy balance, however the mediators of this effect and their…”
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3
SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts
Published in Nature communications (29-07-2021)“…Hedgehog signaling is essential for bone formation, including functioning as a means for the growth plate to drive skeletal mineralization. However, the…”
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MEKK2 mediates aberrant ERK activation in neurofibromatosis type I
Published in Nature communications (11-11-2020)“…Neurofibromatosis type I (NF1) is characterized by prominent skeletal manifestations caused by NF1 loss. While inhibitors of the ERK activating kinases MEK1/2…”
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Hox patterning of the vertebrate rib cage
Published in Development (Cambridge) (15-08-2007)“…Unlike the rest of the axial skeleton, which develops solely from somitic mesoderm, patterning of the rib cage is complicated by its derivation from two…”
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Mutant p53 Amplifies Epidermal Growth Factor Receptor Family Signaling to Promote Mammary Tumorigenesis
Published in Molecular cancer research (01-04-2015)“…The EGFR family (ErbB2/Her2 and EGFR/ErbB1/Her1) often modulates the transcriptional program involved in promoting mammary tumorigenesis. In humans, the…”
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A Hox-Eya-Pax Complex Regulates Early Kidney Developmental Gene Expression
Published in Molecular and Cellular Biology (01-11-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma
Published in PloS one (16-08-2011)“…Organogenesis requires the differentiation and integration of distinct populations of cells to form a functional organ. In the kidney, reciprocal interactions…”
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Schnurri-3 inhibition rescues skeletal fragility and vascular skeletal stem cell niche pathology in the OIM model of osteogenesis imperfecta
Published in Bone Research (26-08-2024)“…Osteogenesis imperfecta (OI) is a disorder of low bone mass and increased fracture risk due to a range of genetic variants that prominently include mutations…”
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Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements
Published in Development (Cambridge) (15-11-2010)“…Hox11 genes are essential for zeugopod skeletal element development but their roles in synovial joint formation remain largely unknown. Here, we show that the…”
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An angiogenic approach to osteoanabolic therapy targeting the SHN3-SLIT3 pathway
Published in Bone (New York, N.Y.) (01-07-2023)“…Often, disorders of impaired bone formation involve not only a cell intrinsic defect in the ability of osteoblasts to form bone, but moreover a broader…”
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A vertebral skeletal stem cell lineage driving metastasis
Published in Nature (London) (21-09-2023)“…Vertebral bone is subject to a distinct set of disease processes from long bones, including a much higher rate of solid tumour metastases 1 – 4 . The basis for…”
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Development of Murine Anterior Interbody and Posterolateral Spinal Fusion Techniques
Published in Journal of bone and joint surgery. American volume (17-04-2024)“…Multiple animal models have previously been utilized to investigate anterior fusion techniques, but a mouse model has yet to be developed. The purpose of this…”
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A multi-stem cell basis for craniosynostosis and calvarial mineralization
Published in Nature (London) (28-09-2023)“…Craniosynostosis is a group of disorders of premature calvarial suture fusion. The identity of the calvarial stem cells (CSCs) that produce fusion-driving…”
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15
Characterization of a novel Hoxa5eGFP mouse line
Published in Developmental dynamics (01-04-2023)“…Background Hox genes encode transcription factors that are important for establishing the body plan. Hoxa5 is a member of the mammalian Hox5 paralogous group…”
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Histone demethylase LSD1 is critical for endochondral ossification during bone fracture healing
Published in Science advances (01-11-2020)“…Bone fracture is repaired predominantly through endochondral ossification. However, the regulation of endochondral ossification by key factors during fracture…”
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The Zeb proteins δEF1 and Sip1 may have distinct functions in lens cells following cataract surgery
Published in Investigative ophthalmology & visual science (01-08-2014)“…Posterior capsular opacification (PCO), the most prevalent side effect of cataract surgery, occurs when residual lens epithelial cells (LECs) undergo fiber…”
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Non-homeodomain regions of Hox proteins mediate activation versus repression of Six2 via a single enhancer site in vivo
Published in Developmental biology (01-11-2009)“…Hox genes control many developmental events along the AP axis, but few target genes have been identified. Whether target genes are activated or repressed, what…”
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Role of Hox11 genes in anteroposterior patterning of nephrogenic mesenchyme
Published in Developmental biology (15-07-2009)Get full text
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