Search Results - "Yalcintepe, Leman"

Iron alters Ca2+ homeostasis in doxorubicin‐resistant K562 cells by Yalcintepe, Leman, Erdag, Demet, Akbas, Fahri, Kucukkaya, Bahire

“…Iron is an essential trace element especially in cell proliferation, and growth for various cellular events. An increasing amount of research has shown that…”
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The effect of iron on the expression levels of calcium related gene in cisplatin resistant epithelial ovarian cancer cells by Kucukkaya, Bahire, Erdag, Demet, Akbas, Fahri, Yalcintepe, Leman

“…Aim: Anticancer drugs (chemotherapeutics) used in cancer treatment (chemotherapy) lead to drug resistance. This study was conducted to investigate the possible…”
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Variant diphtheria toxin-interleukin-3 fusion proteins with increased receptor affinity have enhanced cytotoxicity against acute myeloid leukemia progenitors by HOGGE, Donna E, YALCINTEPE, Leman, WONG, Siaw-Hui, GERHARD, Brigitte, FRANKEL, Arthur E

“…A fusion protein linking a truncated form of diphtheria toxin (DT(388)) to human interleukin-3 (DT(388)IL3) kills malignant progenitors from some patients with…”
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Effect of CD38 on the multidrug resistance of human chronic myelogenous leukemia K562 cells to doxorubicin by YALÇINTEPE, LEMAN, HALIS, EMRE, ULKU, SIBEL

“…Drug resistance is a serious challenge in cancer chemotherapy. Alterations in the intracellular concentration and homeostasis of calcium (Ca2+) may contribute…”
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Iron alters Ca 2+ homeostasis in doxorubicin-resistant K562 cells by Yalcintepe, Leman, Erdag, Demet, Akbas, Fahri, Kucukkaya, Bahire

“…Iron is an essential trace element especially in cell proliferation, and growth for various cellular events. An increasing amount of research has shown that…”
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Characterization of Lin⁻ALDH (bright) population using Ehrlich ascites tumor cells in mice by Yalçintepe, Leman, Altinel, Pinar, Albeniz, Işil, Yilmaz, Abdullah, Nurten, Rustem

“…Cancer stem cells (CSCs)/tumor initiating cells have been shown to exist in recent studies; however, it is challenging to isolate these cells. The latest…”
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Hemin-dependent induction and internalization of CD38 in K562 cells by Yalcintepe, Leman, Ercelen, Sebnem, Adin-Cinar, Suzan, Badur, Selim, Tiryaki, Demir, Bermek, Engin

“…The cell surface antigen, CD38, is a bifunctional ecto‐enzyme, which is predominantly expressed on hematopoietic cells during differentiation. In the present…”
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Synergistic effect of selenium and genipin triggers viability of 3T3 cells on PVA/Gelatin scaffolds by Erdag, Demet, Koc, Serkan N, Oksuzomer, M Faruk, Yalcintepe, Leman

“…The aim of this study was to reveal the first time synergistic effect of GP and selenium (Se) on 3T3 cells seeded on natural and non-cytotoxic porous scaffolds…”
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Erythrocyte CD38 as a prognostic marker in cancer by Albeniz, Isil, Demir, Ozlem, Türker-Sener, Leyla, Yalçintepe, Leman, Nurten, Rüstem, Bermek, Engin

“…Surface antigen CD38 which is a multifunctional protein with enzymatic and receptorial properties is involved in many processes of cell proliferation and…”
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Expression of interleukin-3 receptor subunits on defined subpopulations of acute myeloid leukemia blasts predicts the cytotoxicity of diphtheria toxin interleukin-3 fusion protein against malignant progenitors that engraft in immunodeficient mice by Yalcintepe, Leman, Frankel, Arthur E., Hogge, Donna E.

“…The interleukin-3 receptor (IL-3R) subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus…”
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Modulation of iron metabolism by iron chelation regulates intracellular calcium and increases sensitivity to doxorubicin by Yalcintepe, Leman, Halis, Emre

“…Increased intracellular iron levels can both promote cell proliferation and death, as such; iron has a "two-sided effect" in the delicate balance of human…”
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Nuclear CD38 in retinoic acid-induced HL-60 cells by Yalcintepe, Leman, Albeniz, Isil, Adin-Cinar, Suzan, Tiryaki, Demir, Bermek, Engin, Graeff, Richard M., Lee, Hon Cheung

“…The cell surface antigen, CD38, is a 45-kDa transmembrane protein which is predominantly expressed on hematopoietic cells during differentiation. As a…”
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Changes in NAD/ADP-ribose metabolism in rectal cancer by Yalcintepe, L, Turker-Sener, L, Sener, A, Yetkin, G, Tiryaki, D, Bermek, E

“…The extent of ADP-ribosylation in rectal cancer was compared to that of the corresponding normal rectal tissue. Twenty rectal tissue fragments were collected…”
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Characterization of Lin−ALDHbright population using Ehrlich ascites tumor cells in mice by Yalçintepe, Leman, Altinel, Pinar, Albeniz, Işil, Yilmaz, Abdullah, Nurten, Rustem

“…Cancer stem cells (CSCs)/tumor initiating cells have been shown to exist in recent studies; however, it is challenging to isolate these cells. The latest…”
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Characterization of Lin^sup -^ALDH^sup bright^ population using Ehrlich ascites tumor cells in mice by Yalçintepe, Leman, Altinel, Pinar, Albeniz, Isil, Yilmaz, Abdullah, Nurten, Rustem

“…Cancer stem cells (CSCs)/tumor initiating cells have been shown to exist in recent studies; however, it is challenging to isolate these cells. The latest…”
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Wortmannin is a potent inhibitor of DNA double strand break but not single strand break repair in Chinese hamster ovary cells by Boulton, Sallyanne, Kyle, Suzanne, Yalçintepe, Leman, Durkacz, Barbara W.

“…Wortmannin, an inhibitor of p110 PI 3-kinase, also inhibits DNA-dependent protein kinase, which is known to mediate DNA double strand break repair. It was…”
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Serum proteins with NAD + glycohydrolase activity and anti-CD38 reactivity – elevated levels in serum of tumour patients by Korkut, Çağatay, Yalçıntepe, Leman, Kiremit-Korkut, Neşe, Uzun-Altınöz, Semire, İşsever, Saliha, Gümüşel, Füsun, Tiryaki, Demir, Bermek, Engin

“…NAD + glycohydrolase activities in serum samples from cancer patients were two- to three-fold higher than the activities in samples from healthy controls…”
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