Search Results - "Yalamarty, Satya Siva Kishan"
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Recent Advances in Tumor Targeting via EPR Effect for Cancer Treatment
Published in Journal of personalized medicine (18-06-2021)“…Cancer causes the second-highest rate of death world-wide. A major shortcoming inherent in most of anticancer drugs is their lack of tumor selectivity…”
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Mechanisms of Resistance and Current Treatment Options for Glioblastoma Multiforme (GBM)
Published in Cancers (01-04-2023)“…Glioblastoma multiforme (GBM) is a highly aggressive form of brain cancer that is difficult to treat due to its resistance to both radiation and chemotherapy…”
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Role of circular RNA and its delivery strategies to cancer – An overview
Published in Journal of controlled release (01-04-2023)“…With the passage of years and the progress of research on ribonucleic acids, the range of forms in which these molecules have been observed grows. One of them,…”
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Developments in Treatment Methodologies Using Dendrimers for Infectious Diseases
Published in Molecules (Basel, Switzerland) (31-05-2021)“…Dendrimers comprise a specific group of macromolecules, which combine structural properties of both single molecules and long expanded polymers. The…”
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Monoclonal Antibody 2C5-Modified Mixed Dendrimer Micelles for Tumor-Targeted Codelivery of Chemotherapeutics and siRNA
Published in Molecular pharmaceutics (04-05-2020)“…Targeted delivery of chemotherapeutics to tumors has the potential to reach a high dose at the tumor while minimizing systemic exposure. Incorporation of…”
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Recent Advances with Precision Medicine Treatment for Breast Cancer including Triple-Negative Sub-Type
Published in Cancers (08-04-2023)“…Breast cancer is a heterogeneous disease with different molecular subtypes. Breast cancer is the second leading cause of mortality in woman due to rapid…”
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Lipid-Based Drug Delivery Systems in Regenerative Medicine
Published in Materials (17-09-2021)“…The most important goal of regenerative medicine is to repair, restore, and regenerate tissues and organs that have been damaged as a result of an injury,…”
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Approaches to Improve EPR-Based Drug Delivery for Cancer Therapy and Diagnosis
Published in Journal of personalized medicine (23-02-2023)“…The innovative development of nanomedicine has promised effective treatment options compared to the standard therapeutics for cancer therapy. However, the…”
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Co-Delivery of siRNA and Chemotherapeutic Drug Using 2C5 Antibody-Targeted Dendrimer-Based Mixed Micelles for Multidrug Resistant Cancers
Published in Pharmaceutics (15-07-2022)“…Multidrug resistance (MDR) observed in tumors significantly hinders the efficacy of chemotherapy. Downregulation of efflux proteins, such as P-glycoprotein…”
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Co-Encapsulation of Drugs for Topical Application-A Review
Published in Molecules (Basel, Switzerland) (01-02-2023)“…Achieving the best possible outcome for the therapy is the main goal of a medicine. Therefore, nanocarriers and co-delivery strategies were invented to meet…”
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Self-Assembled Dual-Targeted Epirubicin-Hybrid Polydopamine Nanoparticles for Combined Chemo-Photothermal Therapy of Triple-Negative Breast Cancer
Published in International journal of nanomedicine (01-01-2020)“…Folic acid and cyclic arginylglycylaspartic acid peptides were introduced to the surface of negatively charged lipid-coated hybrid polydopamine-cysteine cores…”
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Recent advancements in liposome technology
Published in Advanced drug delivery reviews (2020)“…The liposomes have continued to be well-recognized as an important nano-sized drug delivery system with attractive properties, such a characteristic bilayer…”
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Nano Silver-Induced Toxicity and Associated Mechanisms
Published in International journal of nanomedicine (01-01-2022)“…Nano silver is one of the most widely used engineering nanomaterials with antimicrobial activity against bacteria, fungi, and viruses. However, the widespread…”
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Antibody-modified DNase I micelles specifically recognize the neutrophil extracellular traps (NETs) and promote their degradation
Published in Journal of controlled release (01-02-2023)“…Neutrophil extracellular traps (NETs) are structures consisting of decondensed chromatin with associated proteins, including histones and antimicrobial…”
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Recent strategies to overcome breast cancer resistance
Published in Critical reviews in oncology/hematology (01-05-2024)“…Breast cancer is potentially a lethal disease and a leading cause of death in women. Chemotherapy and radiotherapy are the most frequently used treatment…”
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Liposomal Co-delivery of PD-L1 siRNA/Anemoside B4 for Enhanced Combinational Immunotherapeutic Effect
Published in ACS applied materials & interfaces (29-06-2022)“…Combination therapy has gained a lot of attention thanks to its superior activity against cancer. In the present study, we report a cRGD-targeted liposomal…”
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Journal Article -
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Role and Therapeutic Targeting Strategies of Neutrophil Extracellular Traps in Inflammation
Published in International journal of nanomedicine (01-01-2023)“…Neutrophil extracellular traps (NETs) are large DNA reticular structures secreted by neutrophils and decorated with histones and antimicrobial proteins. As a…”
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Co - Delivery of siRNA and Chemotherapeutic Drug using 2C5 Antibody-Targeted Dendrimer-based Mixed Micelles for Multidrug Resistant Cancers
Published 01-01-2023“…Chemotherapy is much less effective in tumors where multidrug resistance (MDR) has been found. To reduce resistance in tumors, small interfering RNA (siRNA)…”
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Dissertation -
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Cisplatin-loaded thermoresponsive liposomes for enhanced anticancer efficacy
Published in Journal of drug delivery science and technology (01-06-2023)“…Thermoresponsive drug delivery systems have been used previously to deliver chemotherapeutic agents to tumors in a hyperthermic microenvironment. The objective…”
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Journal Article