Search Results - "Yalçın, Ayfer"

Altered Levels of Gene Expression of Drug Metabolism Enzymes in Rat Brain Following Kainic Acid Treatment by Yalcin, Ayfer, Turunc, Ezgi, Armagan, Guliz, Kanit, Lutfiye

“…Previous studies have shown that gene expressions can be regulated in the hippocampus of rats after seizures induced by kainic acid (KA). The aim of this study…”
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Changes in the cannabinoid (CB1) receptor expression level and G-protein activation in kainic acid induced seizures by Bojnik, Engin, Turunç, Ezgi, Armağan, Güliz, Kanıt, Lütfiye, Benyhe, Sándor, Yalçın, Ayfer, Borsodi, Anna

“…Summary It has been known for centuries that exogenous cannabinoids, such as tetrahydrocannabinol have anticonvulsant activity. Recent studies have advanced…”
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Studies on Mefenamic Acid Microparticles: Formulation, In Vitro Release, and In Situ Studies in Rats by Sevgi, Ferhan, Yurdasiper, Aysu, Kaynarsoy, Buket, Turunç, Ezgi, Güneri, Tamer, Yalçın, Ayfer

“…In this study, we investigated the in vitro characteristics of mefenamic acid (MA) microparticles as well as their effects on DNA damage. MA-loaded chitosan…”
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STAT-Dependent Upregulation of 12/15-Lipoxygenase Contributes to Neuronal Injury after Stroke by Jung, Joo Eun, Karatas, Hulya, Liu, Yu, Yalcin, Ayfer, Montaner, Joan, Lo, Eng H, van Leyen, Klaus

“…Oxidative stress is a major brain injury mechanism after ischemic stroke. 12/15-lipoxygenase (12/15-LOX) is a key mediator of oxidative stress, contributing to…”
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Establishment and Validation of an Automated System for the Antifactor IIa Assay: A Case Study of Potency Assessment of a Pharmaceutical Gel Formulation by Ozgen, Gokselin, Turk Gezer, Merve, Armagan, Guliz, Ballar Kirmizibayrak, Petek, Yalcin, Ayfer, Ozer, Ozgen, Ozkirim Arslan, Banu, Kayar, Gonul, Dude, Udaya Kumar, Kaymak Ozdemir, Aysegul

“…Antithrombotic agents and anticoagulant drugs, such as those from the heparin family, are employed in clinical settings for the prevention and treatment of…”
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Effects of resveratrol on hydrogen peroxide-induced oxidative stress in embryonic neural stem cells by Konyalioglu, Sibel, Armagan, Guliz, Yalcin, Ayfer, Atalayin, Cigdem, Dagci, Taner

“…Resveratrol, a natural phenolic compound, has been shown to prevent cardiovascular diseases and cancer and exhibit neuroprotective effects. In this study, we…”
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Electrochemical determination of glutathione in plasma at carbon nanotubes based screen printed electrodes by Turunc, Ezgi, Karadeniz, Hakan, Armagan, Guliz, Erdem, Arzum, Yalcin, Ayfer

“…Glutathione (GSH) is a major endogenous antioxidant highly active in human tissues and plays a key role in controlling cellular thiol redox system, maintaining…”
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Gamma‐glutamylcysteine ethyl ester protects cerebral endothelial cells during injury and decreases blood–brain barrier permeability after experimental brain trauma by Lok, Josephine, Leung, Wendy, Zhao, Song, Pallast, Stefanie, van Leyen, Klaus, Guo, Shuzhen, Wang, Xiaoying, Yalcin, Ayfer, Lo, Eng H.

“…J. Neurochem. (2011) 118, 248–255. Oxidative stress is a pathway of injury that is common to almost all neurological conditions. Hence, methods to scavenge…”
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Mu opioid receptor mRNA expression, binding, and functional coupling to G-proteins in human epileptic hippocampus by Cuellar-Herrera, Manola, Velasco, Ana Luisa, Velasco, Francisco, Chavez, Laura, Orozco-Suarez, Sandra, Armagan, Guliz, Turunc, Ezgi, Bojnik, Engin, Yalcin, Ayfer, Benyhe, Sandor, Borsodi, Anna, Alonso-Vanegas, Mario, Rocha, Luisa

“…Mu opioid receptors (MOR) are known to be involved in seizure activity. The main goal of the present study was to characterize the MOR mRNA expression,…”
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The potential antioxidant effect of raloxifene treatment: a study on heart, liver and brain cortex of ovariectomized female rats by Konyalioglu, Sibel, Durmaz, Guliz, Yalcin, Ayfer

“…The antioxidant activity of some compounds buffer the free radicals generated either endogenously or exogenously, thus decreasing the potential damage mediated…”
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Potential neuroprotective effects of 2-hydroxypropyl-β cyclodextrin against amyloid β (1-42)-induced neurotoxicity on the rat hippocampus by Yalcin, Ayfer, Turunc, Ezgi, Kaplan, Mehmet Mahsum, Uyanikgil, Yigit, Erzurumlu, Yalcin, Gavini, Elisabetta, Kanit, Lutfiye

“…The neurodegenerative mechanisms of Alzheimer's disease (AD) are not fully understood, but it is believed that amyloid beta (Aβ) peptide causes oxidative…”
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Effects of nicotinamide treatment on mRNA expression of various enzymes involved in NAD+ metabolism in Aβ(1–42) induced neurodegeneration by Kilicarslan, İrem, Turunc, Ezgi, Kanit, Lutfiye, Yalcin, Ayfer

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P-46 - Effects of nicotinamide treatment on mRNA expression of various enzymes involved in NAD+ metabolism in Aβ(1–42) induced neurodegeneration by Kilicarslan, İrem, Turunc, Ezgi, Kanit, Lutfiye, Yalcin, Ayfer

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P-114 - Potential protective effects of hydroxypropyl-β-cyclodextrin on Aβ (1–42)-induced neurotoxicity by Yalcin, Ayfer, Turunc, Ezgi, Uyanikgil, Yigit, Kanit, Lutfiye, Kaplan, Mehmet M., Erzurumlu, Yalcin, Sevinc, Ege

“…The presence of amyloid β (Aβ) peptide plaques is one of the key events for the neuropathogenesis of Alzheimer disease (AD). High membrane cholesterol…”
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Potential protective effects of hydroxypropyl-β-cyclodextrin on Aβ (1–42)-induced neurotoxicity by Yalcin, Ayfer, Turunc, Ezgi, Uyanikgil, Yigit, Kanit, Lutfiye, Kaplan, Mehmet M., Erzurumlu, Yalcin, Sevinc, Ege

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Neuroprotective Effects of Engineered Polymeric Nasal Microspheres Containing Hydroxypropyl-β-cyclodextrin on β-Amyloid (1-42)-Induced Toxicity by Yalcin, Ayfer, Soddu, Elena, Turunc Bayrakdar, Ezgi, Uyanikgil, Yigit, Kanit, Lutfiye, Armagan, Guliz, Rassu, Giovanna, Gavini, Elisabetta, Giunchedi, Paolo

“…β-Amyloid (Aβ) plaques are the key neurotoxic assemblies in Alzheimer disease. It has been suggested that an interaction occurs between membrane cholesterol…”
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Effect of GCEE or GCEE-loaded microspheres Administration on the Levels of Glutathione and Thiol Redox Molecules in Rat Brain by Yalcin, Ayfer, Ezgi Turunc, Sinem, Yildiz Turkyilmaz, Gulbeyaz, Kanit, Lutfiye, Karasulu, Ercument

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P 065 - Effect of GCEE or GCEE-loaded microspheres Administration on the Levels of Glutathione and Thiol Redox Molecules in Rat Brain by Yalcin, Ayfer, Ezgi Turunc, Sinem, Yildiz Turkyilmaz, Gulbeyaz, Kanit, Lutfiye, Karasulu, Ercument

“…It is known that activity of thiol redox molecules such as Trx, TrxR and Ref-1 is regulated by glutathione (GSH). γ-glutamylcysteine ethyl ester (GCEE) is a…”
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Neuroprotection by mefenamic acid against D-serine: involvement of oxidative stress, inflammation and apoptosis by Armagan, Guliz, Turunc, Ezgi, Kanit, Lutfiye, Yalcin, Ayfer

“…Mefenamic acid, a non-steroidal antiinflammatory drug (NSAID), directly and dose-dependently exhibits neuroprotective activity. In our study, we investigated…”
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Ex vivo protective effects of nicotinamide and 3-aminobenzamide on rat synaptosomes treated with Aβ(1-42) by Turunc Bayrakdar, Ezgi, Armagan, Guliz, Uyanikgil, Yigit, Kanit, Lutfiye, Koylu, Ersin, Yalcin, Ayfer

“…Alzheimer's disease (AD) is the most common form of dementia and is characterized by the presence of senile plaques and neurofibrillary tangles, along with…”
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