Search Results - "Yakubu, Momoh"
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Oxidative stress indices in ASD children in Sub-Sahara Africa
Published in Journal of neurodevelopmental disorders (01-12-2021)“…Abstract Background The pathogenesis of autism spectrum disorder (ASD) remains a medical challenge even in the developed world. Although genetics and…”
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2
Naringenin antihypertensive power is mediated via abrogation of mineralocorticoid receptor (MCR)/ angiotensin converting enzyme (ACE)/ kidney injury molecule (Kim‐1) signaling pathway
Published in The FASEB journal (01-05-2022)“…Hypertension is a condition with chronic elevation of blood pressure and a common preventable risk factor for cardiovascular disease with attendant global…”
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3
Orchidectomy attenuates high-salt diet-induced increases in blood pressure, renovascular resistance, and hind limb vascular dysfunction: role of testosterone
Published in Clinical and experimental pharmacology & physiology (01-09-2016)“…Summary Sex hormone‐dependent vascular reactivity is an underlying factor contributing to sex differences in salt‐dependent hypertension. This study evaluated…”
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4
Hypotensive and antihypertensive effects of an aqueous extract from Guinep fruit (Melicoccus bijugatus Jacq) in rats
Published in Scientific reports (29-10-2020)“…Melicoccus bijugatus Jacq (Mb) has been reported to have cardiovascular modulatory effects. In this study, we evaluated the antihypertensive effects and…”
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5
Clofibrate, a Peroxisome Proliferator–Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride–Induced Toxicity
Published in Biological trace element research (01-03-2022)“…Sodium fluoride (NaF) is one of the neglected environmental pollutants. It is ubiquitously found in the soil, water, and environment. Interestingly, fluoride…”
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Clofibrate, a PPAR‐α agonist, abrogates sodium fluoride‐induced neuroinflammation, oxidative stress, and motor incoordination via modulation of GFAP/Iba‐1/anti‐calbindin signaling pathways
Published in Environmental toxicology (01-02-2020)“…Fluoride is an environmental contaminant that is ubiquitously present in air, water, and soil. It is commonly added in minute quantity to drinking water,…”
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7
Naringin mitigates testicular injury and associated neuronal toxicity in lead-exposed cockerel chicks
Published in Avicenna journal of phytomedicine (01-01-2024)“…Lead (Pb) poisoning affects multiple organs including the reproductive system. The experiment was performed to explore the protective effect of naringin on…”
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Antihypertensive action of Launaea taraxacifolia and its molecular mechanism of action
Published in Pakistan journal of pharmaceutical sciences (01-11-2022)“…Launaea taraxacifolia has been traditionally used for the management of conditions such as cardiovascular, respiratory, and metabolic diseases. High blood…”
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Cardiovascular and renal oxidative stress-mediated toxicities associated with bisphenol-A exposures are mitigated by Curcuma longa in rats
Published in Avicenna journal of phytomedicine (01-03-2024)“…Rhizome (CLR), due to its potent antioxidant phytochemical constituents, was investigated for its effects on bisphenol A (BPA)-induced cardiovascular and renal…”
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Antihypertensive effect of methanol leaf extract of Azadirachta indica is mediated through suppression of renal caspase 3 expressions on Nω-Nitro-l-arginine methyl ester induced hypertension
Published in Pharmacognosy research (01-10-2020)“…Background: Azadirachta indica (AI) Adr Juss (Meliaceae), known as neem, has been used traditionally for the treatment of various disease conditions including…”
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11
Luteolin‐mediated Kim‐1/NF‐kB/Nrf2 signaling pathways protects sodium fluoride‐induced hypertension and cardiovascular complications
Published in BioFactors (Oxford) (01-11-2018)“…The use of sodium fluoride (NaF) as a major ingredient for tooth paste, mouth wash, and mouth rinse has become inevitable in our day‐to‐day life. However,…”
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12
Kolaviron, biflavonoid complex from the seed of Garcinia kola attenuated angiotensin II- and lypopolysaccharide-induced vascular smooth muscle cell proliferation and nitric oxide production
Published in Pharmacognosy research (01-03-2016)“…Introduction: Kolaviron (KV), a biflavonoid extract from Garcinia kola seeds has been reported to possess anti-inflammatory, anti-oxidant, hepato-protective,…”
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Luteolin mitigates potassium dichromate‐induced nephrotoxicity, cardiotoxicity and genotoxicity through modulation of Kim‐1/Nrf2 signaling pathways
Published in Environmental toxicology (01-11-2021)“…Environmental and occupational exposure to chromium compounds has become potential aetiologic agent for kidney disease with excessive generation of free…”
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14
peroxisome proliferator-activated receptor alpha activation-mediated regulation of endothelin-1 production via nitric oxide and protein kinase C signaling pathways in piglet cerebral microvascular endothelial cell culture
Published in The Journal of pharmacology and experimental therapeutics (01-02-2007)“…Elevated endothelin (ET)-1 has been implicated in cerebrovascular complications following brain trauma characterized by dysregulation of endothelial nitric…”
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15
Cardioprotective effects and antioxidant status of Andrographis paniculata in isoproterenol-induced myocardial infarction in rats
Published in Journal of Medicinal Plants for Economic Development (01-01-2019)“…Abstract only…”
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Ameliorative effect of Rutin on sodium fluoride‐induced hypertension through modulation of Kim‐1/NF‐κB/Nrf2 signaling pathway in rats
Published in Environmental toxicology (01-12-2018)“…Sodium fluoride is one of the neglected environmental contaminants. Inorganic fluorides in the environment are found in the air, water, and land. In the study,…”
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17
Ameliorative effects of glycine on cobalt chloride‐induced hepato‐renal toxicity in rats
Published in Animal models and experimental medicine (01-04-2023)“…Background The important roles of liver and kidney in the elimination of injurious chemicals make them highly susceptible to the noxious activities of various…”
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18
Annona muricata mitigates glycerol-induced nephrotoxicities in male albino rats through signaling pathways of angiotensin conversion enzyme, kidney injury molecule-1, and antioxidant properties
Published in Scientific African (01-07-2022)“…The ameliorative effect of Annona muricata in glycerol-induced acute kidney injury in laboratory rats was evaluated. Thirty albino rats were used and were…”
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Methanol leaf extract of Momordica charantia protects alloxan-induced hepatopathy through modulation of caspase-9 and interleukin-1β signaling pathways in rats
Published in Veterinary World (01-08-2020)“…is a highly valued plant, widely distributed in the tropical and subtropical regions. The plant is reported to have a wide range of medicinal uses. This study…”
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Kolaviron attenuated arsenic acid induced-cardiorenal dysfunction via regulation of ROS, C-reactive proteins (CRP), cardiac troponin I (CTnI) and BCL2
Published in Journal of Traditional and Complementary Medicine (01-07-2018)“…Arsenic acid is one of the abundant environmental pollutants present in soil, water and the air. Undoubtedly, it has found its way to the food chain in which…”
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