Search Results - "Yakovlev, Igor P."

Chromone-Containing Allylmorpholines Influence Ion Channels in Lipid Membranes via Dipole Potential and Packing Stress by Efimova, Svetlana S., Martynyuk, Vera A., Zakharova, Anastasiia A., Yudintceva, Natalia M., Chernov, Nikita M., Yakovlev, Igor P., Ostroumova, Olga S.

“…Herein, we report that chromone-containing allylmorpholines can affect ion channels formed by pore-forming antibiotics in model lipid membranes, which…”
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1,3-Thiazine, 1,2,3,4-Dithiadiazole, and Thiohydrazide Derivatives Affect Lipid Bilayer Properties and Ion-Permeable Pores Induced by Antifungals by Zakharova, Anastasiia A., Efimova, Svetlana S., Yuskovets, Valeriy N., Yakovlev, Igor P., Sarkisyan, Zara M., Ostroumova, Olga S.

“…Over the past decade, thiazines, thiadiazoles, and thiohydrazides have attracted increasing attention due to their sedative, antimicrobial, antiviral,…”
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C,N‐Diarylformamidines as Valuable Building Blocks in the Synthesis of Heterocyclic Compounds by Trukhanova, Yulia A., Chernov, Nikita M., Kuvaeva, Elena V., Yakovlev, Igor P.

“…Obtaining highly functionalized heterocyclic structures is an important topic of modern organic synthesis, as it reveals the possibility of constructing more…”
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Dithiadiazole derivative 3-(4-nitrophenyl)-5-phenyl-3H-1,2,3,4-dithiadiazole-2-oxide – Novel modulator of store-operated calcium entry by Grekhnev, Dmitriy A., Novikova, Iuliia V., Krisanova, Alena V., Yuskovets, Valeriy N., Chernov, Nikita M., Yakovlev, Igor P., Kaznacheyeva, Elena V., Vigont, Vladimir A.

“…Pathological calcium homeostasis accompanies the development of a large number of different diseases, therefore, the search for new modulators of calcium…”
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1,2,3,4-dithiadiazole derivatives as a novel class of calcium signaling modulators by Novikova, Iuliia V, Grekhnev, Dmitriy A, Oshkolova, Arina, Nomerovskaya, Maria A, Kolesnikov, Dmitrii O, Krisanova, Alena V, Yuskovets, Valeriy N, Chernov, Nikita M, Yakovlev, Igor P, Kaznacheyeva, Elena V, Vigont, Vladimir A

“…Aberrant calcium signaling is associated with a diverse range of pathologies, including cardiovascular and neurodegenerative diseases, diabetes, cancer, etc……”
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Synthetic Route to 4,4a‐ and 3,4‐Dihydroxanthones through [4+2] Cycloaddition and Base‐Assisted Sigmatropic Rearrangement by Chernov, Nikita M., Shutov, Roman V., Sharoyko, Vladimir V., Kuz'mich, Nikolay N., Belyakov, Alexander V., Yakovlev, Igor P.

“…The [4+2] cycloaddition of chromone‐fused dienes with enamines was found to be an efficient method for the synthesis of 4,4a‐ and 3,4‐dihydroxanthone…”
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A Flexible Synthetic Approach to Fluorescent Chromeno[4,3‐b]pyridines and Pyrano[3,2‐c]chromenes from Electron‐Deficient 3‐Vinylchromones by Chernov, Nikita M., Shutov, Roman V., Sipkina, Nadezhda Yu, Krivchun, Maxim N., Yakovlev, Igor P.

“…We report a flexible approach to the synthesis of phenanthrene‐like heterocycles through organocatalytic ANRORC (Addition of the Nucleophile, Ring Opening, and…”
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Synthesis of Chromone‐Containing Allylmorpholines through a Morita–Baylis–Hillman‐Type Reaction by Chernov, Nikita M., Shutov, Roman V., Barygin, Oleg I., Dron, Mikhail Y., Starova, Galina L., Kuz'mich, Nikolay N., Yakovlev, Igor P.

“…The first example of an unusual addition of chromone‐substituted acrylic acid to enamines is described. The process shows high versatility concerning both…”
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The reaction of 4-hydroxy-6H-1,3-oxazin-6-ones with amidines – a route to access new 1,3,5-triazine derivatives by Levshukova, Polina O., Kolesnik, Denis A., Dosina, Margarita O., Yakovlev, Igor P., Tunguskova, Lidiya A., Kuvaeva, Elena V., Semakova, Tamara L., Ksenofontova, Galina V., Pokhodnya, Yurii G.

“…The reaction of 2-aryl-5-methyl-4-hydroxy-6 H -1,3-oxazin-6-ones with 1,3-binucleophilic reagents acetamidine and benzamidine was studied. It was established…”
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Facile Directed Synthesis of (Z)‐1‐(Aryl(arylimino)methyl)piperidine‐2,6‐diones from C,N‐Diarylformamidines by Trukhanova, Yulia A., Spiridonova, Dar'ya V., Kuvaeva, Elena V., Chernov, Nikita M., Alekseeva, Galina M., Sopova, Marina V., Fedorova, Elena V., Yakovlev, Igor P.

“…A simple methodology has been developed for the synthesis of previously unstudied N‐substituted glutarimide derivatives –…”
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Reactions of Arylpropynehydrazides with Substituted Malonyl Chlorides: A Route to Pyrazolo-Condensed 1,3-Oxazines by Petina, Olga A., Yakovlev, Igor P., Geffken, Detlef

“…Reaction of phenylpropynehydrazide with dimethylmalonyl chloride furnished the corresponding 4,4‐dimethyl‐1‐(3‐phenylprop‐2‐ynoyl)pyrazolidine‐3,5‐dione, which…”
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Tandem Ring‐Opening/Double Ring‐Closing Synthesis of 1,2,4‐Triazolo[1,5‐a]pyridines from Chromone‐Containing Acrylonitriles by Chernov, Nikita M., Kustin, Roman P., Pypa, Yulia V., Anisimov, Sergej O., Spiridonova, Dar'ya V., Shutov, Roman V., Yakovlev, Igor P.

“…We studied a reaction of chromone‐containing acrylonitriles and cyanoacrylates with acid hydrazides. This reaction turned out to be a method for the synthesis…”
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Tandem Ring‐Opening/Double Ring‐Closing Synthesis of 1,2,4‐Triazolopyridines from Chromone‐Containing Acrylonitriles by Chernov, Nikita M, Kustin, Roman P, Pypa, Yulia V, Anisimov, Sergej O, Spiridonova, Dar'ya V, Shutov, Roman V, Yakovlev, Igor P

“…We studied a reaction of chromone‐containing acrylonitriles and cyanoacrylates with acid hydrazides. This reaction turned out to be a method for the synthesis…”
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Attestation of the primary standard sample of a new analgesic agent 1-phenyl(phenylimino)methyl) pyrrolidine-2,5-dione, development and validation of a method for quantitative determination of the substance by HPLC by Trukhanova, Yulia.A., Alekseeva, Galina M., Yakovlev, Igor P., Spiridonova, Dar'ya V.

“…[Display omitted] •1-Phenyl(phenylimino)methyl)pyrrolidine-2,5-dione primary standard certified.•Conditions for HPLC analysis were developed for the…”
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Fluorescent 5 H ‐Pyrano[3,2‐ c ]chromenes: Synthesis, Photophysical Properties and Sensing of Nucleophilic Anions by Chernov, Nikita M., Panov, Maxim S., Domotskaya, Mariya Yu, Spiridonova, Dar'ya V., Chistyi, Leonid S., Shutov, Roman V., Nikolaev, Dmitrii M., Ryazantsev, Mikhail N., Yakovlev, Igor P.

“…We report the development of a convenient organocatalytic method for the synthesis of 5 H ‐pyrano[3,2‐ c ]chromenes from chromone‐containing acrylates and…”
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Fluorescent 5H‐Pyrano[3,2‐c]chromenes: Synthesis, Photophysical Properties and Sensing of Nucleophilic Anions by Chernov, Nikita M., Panov, Maxim S., Domotskaya, Mariya Yu, Spiridonova, Dar'ya V., Chistyi, Leonid S., Shutov, Roman V., Nikolaev, Dmitrii M., Ryazantsev, Mikhail N., Yakovlev, Igor P.

“…We report the development of a convenient organocatalytic method for the synthesis of 5H‐pyrano[3,2‐c]chromenes from chromone‐containing acrylates and ethyl…”
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The Practice of Attestation Primary Reference Samples on the Example of a New Potential Analgesic Agent – 2‐({[4‐Nitrophenyl] imino}(phenyl)methyl)isoindoline‐1,3‐dione by Trukhanova, Yulia A., Terninko, Inna I., Spiridonova, Dar'ya V., Generalova, Yulia E., Ermachenkov, Roman, Alekseeva, Galina M., Kuvaeva, Elena V., Yakovlev, Igor P.

“…Attestation of primary reference standard of a potential analgesic agent ‐ 2‐({[4‐nitrophenyl]imino}(phenyl)methyl)isoindoline‐1,3‐dione (TJ‐8_215) for the…”
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Synthesis and Biological Activity of New Derivatives of Isoindoline-1,3-dione as Non-Steroidal Analgesics by Yulia A. Trukhanova, Denis A. Kolesnik, Elena V. Kuvaeva, Galina V. Ksenofontova, Marina V. Sopova, Igor P. Yakovlev

“…A simple method for the synthesis of new derivatives of isoindoline-1,3-dione is developed in this study, which consists of the interaction of…”
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Synthesis and antihypoxic activity of new diphenylguanidine derivatives by Trukhanova, Yulia. A., Spiridonova, Dar'ya V., Yuskovets, Valery N., Yakovlev, Igor P., Kuvaeva, Elena V., Ivkin, Dmitry Yu, Semakova, Tamara L.

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An efficient synthesis and characterization of novel (Z)-1-phenyl(arylamino)methylpyrrolidine-2,5-dione derivatives as potential analgesic agents by Trukhanova, Yulia A., Kolesnik, Denis A., Yakovlev, Igor P., Spiridonova, Dar'ya V., Yuskovets, Valery N., Kuvaeva, Elena V., Ksenofontova, Galina V., Semakova, Tamara L.

“…The reaction of N-arylbenzenecarboximidamides 1a-e with succinic anhydride 2 was studied, leading to the formation of…”
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