Search Results - "Yakovenko, Olga"
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Evaluating stored platelet shape change using imaging flow cytometry
Published in Platelets (Edinburgh) (01-12-2023)“…Platelets are routinely stored at room temperature for 5-7 days before transfusion. Stored platelet quality is traditionally assessed by Kunicki's morphology…”
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FimH Forms Catch Bonds That Are Enhanced by Mechanical Force Due to Allosteric Regulation
Published in The Journal of biological chemistry (25-04-2008)“…The bacterial adhesive protein, FimH, is the most common adhesin of Escherichia coli and mediates weak adhesion at low flow but strong adhesion at high flow…”
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3
Specific electrostatic interactions between charged amino acid residues regulate binding of von Willebrand factor to blood platelets
Published in The Journal of biological chemistry (10-11-2017)“…The plasma protein von Willebrand factor (VWF) is essential for hemostasis initiation at sites of vascular injury. The platelet-binding A1 domain of VWF is…”
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4
Inactive conformation enhances binding function in physiological conditions
Published in Proceedings of the National Academy of Sciences - PNAS (11-08-2015)“…Many receptors display conformational flexibility, in which the binding pocket has an open inactive conformation in the absence of ligand and a tight active…”
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5
Recognition of specific sialoglycan structures by oral streptococci impacts the severity of endocardial infection
Published in PLoS pathogens (24-06-2019)“…Streptococcus gordonii and Streptococcus sanguinis are primary colonizers of the tooth surface. Although generally non-pathogenic in the oral environment, they…”
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Interdomain Interaction in the FimH Adhesin of Escherichia coli Regulates the Affinity to Mannose
Published in The Journal of biological chemistry (10-08-2007)“…FimH is a mannose-specific adhesin located on the tip of type 1 fimbriae of Escherichia coli that is capable of mediating shear-enhanced bacterial adhesion…”
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Uncoiling mechanics of Escherichia coli type I fimbriae are optimized for catch bonds
Published in PLoS biology (01-09-2006)“…We determined whether the molecular structures through which force is applied to receptor-ligand pairs are tuned to optimize cell adhesion under flow. The…”
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Catch-Bond Model Derived from Allostery Explains Force-Activated Bacterial Adhesion
Published in Biophysical journal (01-02-2006)“…High shear enhances the adhesion of Escherichia coli bacteria binding to mannose coated surfaces via the adhesin FimH, raising the question as to whether FimH…”
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9
The bacterial fimbrial tip acts as a mechanical force sensor
Published in PLoS biology (01-05-2011)“…There is increasing evidence that the catch bond mechanism, where binding becomes stronger under tensile force, is a common property among non-covalent…”
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10
Integrin-like Allosteric Properties of the Catch Bond-forming FimH Adhesin of Escherichia coli
Published in The Journal of biological chemistry (21-03-2008)“…FimH is the adhesive subunit of type 1 fimbriae of the Escherichia coli that is composed of a mannose-binding lectin domain and a fimbria-incorporating pilin…”
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11
Comparative Structure-Function Analysis of Mannose-Specific FimH Adhesins from Klebsiella pneumoniae and Escherichia coli
Published in Journal of Bacteriology (01-11-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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12
Adaptive mutations in the signal peptide of the type 1 fimbrial adhesin of uropathogenic Escherichia coli
Published in Proceedings of the National Academy of Sciences - PNAS (05-08-2008)“…Signal peptides (SPs) are critical for protein transport across cellular membranes, have a highly conserved structure, and are cleaved from the mature protein…”
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13
INTRAPERSONAL FACTORS AFFECTING THE SUBJECTIVE WELL-BEING OF STUDENT YOUTH
Published in International Journal of Social and Educational Innovation (01-04-2024)“…The article explores various approaches to understanding the concept of subjective well-being and examines the factors that contribute to achieving a state of…”
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14
Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation
Published in Proceedings of the National Academy of Sciences - PNAS (12-03-2019)“…Pyroptosis is an inflammatory form of programmed cell death following cellular damage or infection. It is a lytic process driven by gasdermin D-mediated…”
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15
Local and Trans-oceanic Tsunamis in the Bering and Chukchi Seas Based on Numerical Modeling
Published in Pure and applied geophysics (01-05-2023)“…We have examined the tsunami hazard in the Bering and Chukchi seas by determining whether trans-oceanic tsunamis penetrate into these regions through the…”
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Recombinant FimH Adhesin Demonstrates How the Allosteric Catch Bond Mechanism Can Support Fast and Strong Bacterial Attachment in the Absence of Shear
Published in Journal of molecular biology (11-06-2022)“…The FimH protein of Escherichia coli is a model two-domain adhesin that is able to mediate an allosteric catch bond mechanism of bacterial cell attachment,…”
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Recombinant FimH Adhesin Demonstrates How the Allosteric Catch Bond Mechanism Can Support Fast and Strong Bacterial Attachment in the Absence of Shear
Published in Journal of molecular biology (15-09-2022)“…[Display omitted] •Bacteria use adhesive proteins to bind host cell receptors to cause infection.•Both fast and strong binding is mediated by a switch in the…”
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Serine-Rich Repeat Adhesins Mediate Shear-Enhanced Streptococcal Binding to Platelets
Published in Infection and immunity (01-06-2018)“…The binding of bacteria to platelets is thought to be a central event in the pathogenesis of infective endocarditis. The serine-rich repeat (SRR) glycoproteins…”
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Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Pyroptosis is an inflammatory form of programmed cell death following cellular damage or infection. It is a lytic process driven by gasdermin…”
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20
Molecular Basis for the Pro-Thrombotic Activity of Von Willebrand Factor Under Inflammatory Conditions
Published in Blood (02-12-2016)“…Inflammation is a ubiquitous phenomenon, resulting from such common disease states as obesity, injury, and sepsis, and it is associated with an elevated risk…”
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