Search Results - "Yakıcıer, Mustafa Cengiz"
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Chromosome 22q12.1 microdeletions: confirmation of the MN1 gene as a candidate gene for cleft palate
Published in European journal of human genetics : EJHG (01-01-2016)“…We report on seven novel patients with a submicroscopic 22q12 deletion. The common phenotype constitutes a contiguous gene deletion syndrome on chromosome…”
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Toward In Vitro Epigenetic Drug Design for Thyroid Cancer: The Promise of PF-03814735, an Aurora Kinase Inhibitor
Published in Omics (Larchmont, N.Y.) (01-10-2019)“…Thyroid cancer (TC) is a very common malignancy worldwide. Chief among the innovative molecular drug targets for TC are epigenetic modifications. Increased…”
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An alternatively spliced PD-L1 isoform PD-L1∆3, and PD-L2 expression in breast cancers: implications for eligibility scoring and immunotherapy response
Published in Cancer Immunology, Immunotherapy (01-12-2023)“…Targeting PD-1/PD-L1 has shown substantial therapeutic response and unprecedented long-term durable responses in the clinic. However, several challenges…”
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Association of Pre-miRNA-499 rs3746444 and Pre-miRNA-146a rs2910164 Polymorphisms and Susceptibility to Behcet's Disease
Published in Genetic testing and molecular biomarkers (01-08-2015)“…MiRNAs and NFKB1 are well-known immune response and inflammation regulators. MiRNA gene polymorphisms may affect miRNA biogenesis and function and, may thus,…”
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Analyses of Copy Number Variations in Myxopapillary Ependymomas of Cauda Equina
Published in Turkish neurosurgery (01-01-2020)“…To identify the copy number variations that are specific to myxopapillary ependymomas (MPEs) of the cauda equina. The patient cohort included five patients who…”
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Role of FLT3 in the proliferation and aggressiveness of hepatocellular carcinoma
Published in Turkish journal of medical sciences (01-01-2016)“…Previously we showed that Fms-like tyrosine kinase (FLT3) changes its cellular localization upon partial hepatectomy, suggesting a role in liver regeneration…”
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Mdm2 Snp309 G allele displays high frequency and inverse correlation with somatic P53 mutations in hepatocellular carcinoma
Published in Mutation research (03-02-2010)“…Loss of function of the p53 protein, which may occur through a range of molecular events, is critical in hepatocellular carcinoma (HCC) evolution. MDM2, an…”
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