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Forced expression of Hnf4a induces hepatic gene activation through directed differentiation
Published in Biochemical and biophysical research communications (05-08-2016)“…Embryonic stem (ES) cells are capable of unlimited self-renewal and have a diverse differentiation potential. These unique features make ES cells as an…”
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Forced expression of Hnf1b/Foxa3 promotes hepatic fate of embryonic stem cells
Published in Biochemical and biophysical research communications (20-05-2016)“…Embryonic stem (ES) cell-derived hepatocytes have the potential to be used for basic research, regenerative medicine, and drug discovery. Recent reports…”
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Role of immune responses in the development of NAFLD-associated liver cancer and prospects for therapeutic modulation
Published in Journal of hepatology (01-08-2023)“…The liver is the central metabolic organ of the body, regulating energy and lipid metabolism, while also having potent immunological functions. Overwhelming…”
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Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling
Published in Journal of hepatology (01-08-2023)“…The progression of non-alcoholic steatohepatitis (NASH) to fibrosis and hepatocellular carcinoma (HCC) is aggravated by auto-aggressive T cells. The gut-liver…”
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Mutations in the E2 and NS5A regions in patients infected with hepatitis C virus genotype 1a and their correlation with response to treatment
Published in Journal of medical virology (01-08-2011)“…Heterogeneity of subgenomic regions of hepatitis C virus (HCV) may be associated with response to interferon (IFN) therapy. The amino acid sequences of the…”
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