Search Results - "Yagnik, Bhrugu"
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EpiMix Based Novel Vaccine Candidate for Shigella: Evidence of Prophylactic Immunity in Balb/c Mice
Published in International journal of peptide research and therapeutics (01-06-2021)“…Multidrug resistant Shigella is one of the leading causes of mortality in children and infants. Availability of vaccine could prevent the Shigella infection…”
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Dual recombinant Lactococcus lactis for enhanced delivery of DNA vaccine reporter plasmid pPERDBY
Published in Microbiology and immunology (01-04-2017)“…ABSTRACT Food grade Lactococcus lactis has been widely used as an antigen and DNA delivery vehicle. We have previously reported the use of non‐invasive L…”
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Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure
Published in Frontiers in immunology (13-07-2022)“…Early initiation of antiretroviral therapy (ART) significantly improves clinical outcomes and reduces mortality of infants/children living with HIV. However,…”
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Microbubble-Mediated Enhanced Delivery of Curcumin to Cervical Cancer Cells
Published in ACS omega (31-10-2018)“…The major bottleneck in the current chemotherapy treatment of cancer is the low bioavailability and high cytotoxicity. Targeted delivery of drug to the cancer…”
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Association of dental and skeletal fluorosis with calcium intake and serum vitamin D concentration in adolescents from a region endemic for fluorosis
Published in Indian journal of endocrinology and metabolism (01-01-2017)“…Context: Fluorosis is controlled by the duration of fluoride exposure and calcium and Vitamin D nutrition status. Aim: To examine (a) prevalence of dental and…”
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Oral immunization with LacVax® OmpA induces protective immune response against Shigella flexneri 2a ATCC 12022 in a murine model
Published in Vaccine (21-05-2019)“…•LacVax® OmpA elicited humoral and cellular immune responses in BALB/c mice.•Oral immunization with LacVax® OmpA elicited sIgA, a hallmark of mucosal…”
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Immunoinformatic Identification of Potential Epitopes
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2020)“…Immunoinformatic plays a pivotal role in vaccine design and development. While traditional methods are exclusively depended on immunological experiments, they…”
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In vivo delivery of pPERDBY to BALB/c mice by LacVax®DNA-I and comparison of elicited immune response with conventional immunization methods
Published in Gene therapy (01-10-2018)“…The non-invasive food grade Lactococcus lactis ( L. lactis ) represents a safe and attractive alternative to invasive pathogens for the delivery of plasmid DNA…”
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In vivo delivery of pPERDBY to BALB/c mice by LacVax.sup.[R]DNA-I and comparison of elicited immune response with conventional immunization methods
Published in Gene therapy (01-10-2018)“…The non-invasive food grade Lactococcus lactis (L. lactis) represents a safe and attractive alternative to invasive pathogens for the delivery of plasmid DNA…”
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10
Construction of a new shuttle vector for DNA delivery into mammalian cells using non-invasive Lactococcus lactis
Published in Microbes and infection (01-04-2016)“…Use of food grade Lactococcus lactis (L. lactis) is fast emerging as a safe alternative for delivery of DNA vaccine. To attain efficient DNA delivery, L…”
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11
Shigellosis murine model established by intraperitoneal and intranasal route of administration: a comparative comprehension overview
Published in Microbes and infection (01-01-2017)“…Shigellosis, a major cause of mortality and morbidity, requires development of effective intervention strategy for which animal model mimicking human pathology…”
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Dietary calcium intake influences the relationship between serum 25-hydroxyvitamin D3 (25OHD) concentration and parathyroid hormone (PTH) concentration
Published in Archives of disease in childhood (01-04-2016)“…ObjectivesTo investigate whether dietary calcium intake will modify the relationship between serum 25-hydroxyvitamin D3 (25OHD) with intact serum parathyroid…”
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13
A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence
Published in PLoS pathogens (03-05-2022)“…Transmitted/founder (T/F) HIV-1 envelope proteins (Envs) from infected individuals that developed neutralization breadth are likely to possess inherent…”
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14
PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8 + T cells in lymphoid tissue
Published in Science immunology (10-09-2021)“…During antiretroviral therapy (ART), most of the human immunodeficiency virus (HIV) reservoirs persist in the B cell follicles (BCFs) of lymphoid tissue. Thus,…”
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Factors Affecting Inducible Expression of Outer Membrane Protein A (OmpA) of Shigella dysenteriae Type-1 in Lactococcus lactis Using Nisin Inducible Controlled Expression (NICE)
Published in Indian journal of microbiology (01-03-2016)“…Potential use of Lactococcus lactis (L. lactis) as a heterologous protein expression host as well as for delivery of multiple therapeutic proteins has been…”
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Dietary calcium intake influences the relationship between serum 25-hydroxyvitamin concentration and parathyroid hormone
Published in Archives of disease in childhood (01-04-2016)Get full text
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Dietary calcium intake influences the relationship between serum 25-hydroxyvitamin D 3 (25OHD) concentration and parathyroid hormone (PTH) concentration
Published in Archives of disease in childhood (01-04-2016)“…Objectives To investigate whether dietary calcium intake will modify the relationship between serum 25-hydroxyvitamin D 3 (25OHD) with intact serum parathyroid…”
Get full text
Journal Article