Search Results - "Yaghoobi, Bianca"

Effects of thyroid hormone disruption on the ontogenetic expression of thyroid hormone signaling genes in developing zebrafish (Danio rerio) by Walter, Kyla M., Miller, Galen W., Chen, Xiaopeng, Yaghoobi, Bianca, Puschner, Birgit, Lein, Pamela J.

“…•TH signaling genes are upregulated coordinately with larval zebrafish TH production.•Treatment with T4 or T3 both regulate transcription of TH-responsive…”
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Opportunities and challenges for using the zebrafish to study neuronal connectivity as an endpoint of developmental neurotoxicity by Miller, Galen W., Chandrasekaran, Vidya, Yaghoobi, Bianca, Lein, Pamela J.

“…•Gene-environment interactions influence risk for neurodevelopmental disorders.•Zebrafish may be useful for identifying relevant gene-environment…”
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Ryanodine receptor-active non-dioxin-like polychlorinated biphenyls cause neurobehavioral deficits in larval zebrafish by Yaghoobi, Bianca, Miller, Galen W, Holland, Erika B, Li, Xueshu, Harvey, Danielle, Li, Shuyang, Lehmler, Hans-Joachim, Pessah, Isaac N, Lein, Pamela J

“…Although their production was banned in the United States in 1977, polychlorinated biphenyls (PCBs) continue to pose significant risks to the developing…”
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Implementation of Zebrafish Ontologies for Toxicology Screening by Thessen, Anne E, Marvel, Skylar, Achenbach, J C, Fischer, Stephan, Haendel, Melissa A, Hayward, Kimberly, Klüver, Nils, Könemann, Sarah, Legradi, Jessica, Lein, Pamela, Leong, Connor, Mylroie, J Erik, Padilla, Stephanie, Perone, Dante, Planchart, Antonio, Prieto, Rafael Miñana, Muriana, Arantza, Quevedo, Celia, Reif, David, Ryan, Kristen, Stinckens, Evelyn, Truong, Lisa, Vergauwen, Lucia, Vom Berg, Colette, Wilbanks, Mitch, Yaghoobi, Bianca, Hamm, Jon

“…Toxicological evaluation of chemicals using early-life stage zebrafish ( ) involves the observation and recording of altered phenotypes. Substantial…”
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A non-hallucinogenic psychedelic analogue with therapeutic potential by Cameron, Lindsay P., Tombari, Robert J., Lu, Ju, Pell, Alexander J., Hurley, Zefan Q., Ehinger, Yann, Vargas, Maxemiliano V., McCarroll, Matthew N., Taylor, Jack C., Myers-Turnbull, Douglas, Liu, Taohui, Yaghoobi, Bianca, Laskowski, Lauren J., Anderson, Emilie I., Zhang, Guoliang, Viswanathan, Jayashri, Brown, Brandon M., Tjia, Michelle, Dunlap, Lee E., Rabow, Zachary T., Fiehn, Oliver, Wulff, Heike, McCorvy, John D., Lein, Pamela J., Kokel, David, Ron, Dorit, Peters, Jamie, Zuo, Yi, Olson, David E.

“…The psychedelic alkaloid ibogaine has anti-addictive properties in both humans and animals 1 . Unlike most medications for the treatment of substance use…”
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The efficacy of γ-aminobutyric acid type A receptor (GABA AR) subtype-selective positive allosteric modulators in blocking tetramethylenedisulfotetramine (TETS)-induced seizure-like behavior in larval zebrafish with minimal sedation by Mundy, Paige C., Pressly, Brandon, Carty, Dennis R., Yaghoobi, Bianca, Wulff, Heike, Lein, Pamela J.

“…The chemical threat agent tetramethylenedisulfotetramine (TETS) is a γ-aminobutyric acid type A receptor (GABA AR) antagonist that causes life threatening…”
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Translational toxicology in zebrafish by Tal, Tamara, Yaghoobi, Bianca, Lein, Pamela J.

“…A major goal of translational toxicology is to identify adverse chemical effects and determine whether they are conserved or divergent across experimental…”
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Teratological and Behavioral Screening of the National Toxicology Program 91-Compound Library in Zebrafish (Danio rerio) by Dach, Katharina, Yaghoobi, Bianca, Schmuck, Martin R, Carty, Dennis R, Morales, Kelly M, Lein, Pamela J

“…Abstract To screen the tens of thousands of chemicals for which no toxicity data currently exists, it is necessary to move from in vivo rodent models to…”
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