Search Results - "Yaghi, Asma"

Airway Epithelial Cell Cilia and Obstructive Lung Disease by Yaghi, Asma, Dolovich, Myrna B

“…Airway epithelium is the first line of defense against exposure of the airway and lung to various inflammatory stimuli. Ciliary beating of airway epithelial…”
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Ciliary beating is depressed in nasal cilia from chronic obstructive pulmonary disease subjects by Yaghi, Asma, Zaman, Aisha, Cox, Gerard, Dolovich, Myrna B

“…Summary COPD is characterized by increased cough, mucus production, and airway inflammation. Beating epithelial cell cilia contribute to mucociliary clearance…”
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Cystic fibrosis transmembrane conductance regulator gene abnormalities in patients with asthma and recurrent neutrophilic bronchitis by Goodwin, Jodi, Spitale, Naomi, Yaghi, Asma, Dolovich, Myrna, Nair, Parameswaran

“…The present case series describes four patients with asthma, airway hyperresponsiveness and neutrophilic bronchitis who harboured abnormal cystic fibrosis…”
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Cytochrome P450 metabolites of arachidonic acid but not cyclooxygenase-2 metabolites contribute to the pulmonary vascular hyporeactivity in rats with acute Pseudomonas pneumonia by Yaghi, A, Webb, C D, Scott, J A, Mehta, S, Bend, J R, McCormack, D G

“…We have previously demonstrated depressed vascular contractility in intralobar pulmonary artery (PA) rings isolated from rats with acute Pseudomonas pneumonia…”
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The direct effect of hyperosmolar agents on ciliary beating of human bronchial epithelial cells by Yaghi, Asma, Zaman, Aisha, Dolovich, Myrna B

“…Inhalation of hypertonic saline and mannitol improve mucociliary clearance in patients with bronchiectasis, but little is known about how the relative osmotic…”
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Primary human bronchial epithelial cells grown from explants by Yaghi, Asma, Zaman, Aisha, Dolovich, Myrna

“…Human bronchial epithelial cells are needed for cell models of disease and to investigate the effect of excipients and pharmacologic agents on the function and…”
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Primary Human Bronchial Epithelial Cells Grown from Explants by Yaghi, Asma, Zaman, Aisha, Dolovich, Myrna

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Constrictor-induced translocation of NFAT3 in human and rat pulmonary artery smooth muscle by Yaghi, Asma, Sims, Stephen M

“…The transcription factor nuclear factor of activated T cells (NFAT) resides in the cytoplasm in resting cells and upon stimulation is dephosphorylated,…”
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Differential impairment of vascular reactivity of small pulmonary and systemic arteries in hyperdynamic sepsis by Martin, C M, Yaghi, A, Sibbald, W J, McCormack, D, Paterson, N A

“…We postulated that the redistribution of organ blood flow that occurs in hyperdynamic sepsis is secondary to organ-specific alterations in vascular reactivity…”
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Pulmonary cytochrome P-450 2J4 is reduced in a rat model of acute Pseudomonas pneumonia by Yaghi, Asma, Bradbury, J Alyce, Zeldin, Darryl C, Mehta, Sanjay, Bend, John R, McCormack, David G

“…We previously reported that the levels of epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE) are depressed in microsomes prepared…”
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Excess nitric oxide decreases cytochrome P-450 2J4 content and P-450-dependent arachidonic acid metabolism in lungs of rats with acute pneumonia by Yaghi, Asma, Bend, John R, Webb, Christopher D, Zeldin, Darryl C, Weicker, Sean, Mehta, Sanjay, McCormack, David G

“…Recently, we demonstrated that pulmonary CYP2J4 content, a prominent source of EETs and HETEs formation in rat lungs, is reduced in pneumonia. Therefore, the…”
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Delayed rectifier potassium channels contribute to the depressed pulmonary artery contractility in pneumonia by Yaghi, Asma, Mehta, Sanjay, McCormack, David G

“…AC Burton Vascular Biology Laboratory, Division of Respiratory Medicine, London Health Sciences Centre, London, Ontario, Canada N6A 4G5 We investigated the…”
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Mechanisms of depressed pulmonary artery contractility in a rat model of acute Pseudomonas pneumonia by Yaghi, Asma

“…Pneumonia due to Pseudomonas aeruginosa, a bacterial pathogen, is a major cause of morbidity and mortality in humans. Therefore, understanding the mechanisms…”
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Pulmonary Artery Contractility in Pneumonia: Role of Cyclooxygenase Products and Nitric Oxide by Yaghi, Asma, McCormack, David G

“…The purpose of this study was to determine the effects of aminoguanidine (AG) and meclofenamate (MEC) on depressed contractility of small pulmonary artery (PA)…”
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Vascular reactivity in sepsis: importance of controls and role of nitric oxide by Yaghi, A, Paterson, N A, McCormack, D G

“…We have previously reported differential impairment of pulmonary and systemic vascular contractility in hyperdynamic sepsis. The objectives of this study were…”
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Differential effect of nitric oxide synthase inhibitors on acetylcholine-induced relaxation of rat pulmonary and celiac artery rings by Yaghi, A, Paterson, N A, McCormack, D G

“…The effect of NG-monomethyl-L-arginine (L-NMMA) and N omega-nitro-L-arginine methyl ester (L-NAME) on acetylcholine (ACh) induced relaxation of rat…”
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Human internal thoracic artery reactivity to dopaminergic agents by Myers, M L, Li, G H, Yaghi, A, McCormack, D

“…Vasospasm of the internal thoracic artery (ITA) is common. The purpose of this study was to characterize the vascular reactivity of human ITA to dopaminergic…”
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Human internal thoracic artery reactivity to dopaminergic agents by MYERS, M. L, GUANG-HUE LI, ASMA YAGHI, MCCORMACK, D

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