Search Results - "Yaffe, Zak A."

The S2 subunit of spike encodes diverse targets for functional antibody responses to SARS-CoV-2 by Guenthoer, Jamie, Garrett, Meghan E, Lilly, Michelle, Depierreux, Delphine M, Ruiz, Felicitas, Chi, Margaret, Stoddard, Caitlin I, Chohan, Vrasha, Yaffe, Zak A, Sung, Kevin, Ralph, Duncan, Chu, Helen Y, Matsen, 4th, Frederick A, Overbaugh, Julie

“…The SARS-CoV-2 virus responsible for the COVID-19 global pandemic has exhibited a striking capacity for viral evolution that drives continued evasion from…”
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Elevated binding and functional antibody responses to SARS-CoV-2 in infants versus mothers by Stoddard, Caitlin I., Sung, Kevin, Yaffe, Zak A., Weight, Haidyn, Beaudoin-Bussières, Guillaume, Galloway, Jared, Gantt, Soren, Adhiambo, Judith, Begnel, Emily R., Ojee, Ednah, Slyker, Jennifer, Wamalwa, Dalton, Kinuthia, John, Finzi, Andrés, Matsen, Frederick A., Lehman, Dara A., Overbaugh, Julie

“…Infant antibody responses to viral infection can differ from those in adults. However, data on the specificity and function of severe acute respiratory…”
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HIV-1 protection: Antibodies move in for the kill by Yaffe, Zak A., Overbaugh, Julie

“…Identifying the immune responses needed for protection against HIV is critical to finding an effective vaccine. In this issue of Cell Reports Medicine, Thomas…”
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Higher HIV-1 Env gp120-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity Is Associated with Lower Levels of Defective HIV-1 Provirus by Yucha, Ryan, Litchford, Morgan L, Fish, Carolyn S, Yaffe, Zak A, Richardson, Barbra A, Maleche-Obimbo, Elizabeth, John-Stewart, Grace, Wamalwa, Dalton, Overbaugh, Julie, Lehman, Dara A

“…A cure for HIV-1 (HIV) remains unrealized due to a reservoir of latently infected cells that persist during antiretroviral therapy (ART), with reservoir size…”
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Reconstruction of a polyclonal ADCC antibody repertoire from an HIV-1 non-transmitting mother by Yaffe, Zak A., Ding, Shilei, Sung, Kevin, Chohan, Vrasha, Marchitto, Lorie, Doepker, Laura, Ralph, Duncan, Nduati, Ruth, Matsen, Frederick A., Finzi, Andrés, Overbaugh, Julie

“…Human natural history and vaccine studies support a protective role of antibody dependent cellular cytotoxicity (ADCC) activity against many infectious…”
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Improved HIV-positive infant survival is correlated with high levels of HIV-specific ADCC activity in multiple cohorts by Yaffe, Zak A., Naiman, Nicole E., Slyker, Jennifer, Wines, Bruce D., Richardson, Barbra A., Hogarth, P. Mark, Bosire, Rose, Farquhar, Carey, Ngacha, Dorothy Mbori, Nduati, Ruth, John-Stewart, Grace, Overbaugh, Julie

“…Defining immune responses that protect humans against diverse HIV strains has been elusive. Studying correlates of protection from mother-to-child transmission…”
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phippery: a software suite for PhIP-Seq data analysis by Galloway, Jared G, Sung, Kevin, Minot, Samuel S, Garrett, Meghan E, Stoddard, Caitlin I, Willcox, Alexandra C, Yaffe, Zak A, Yucha, Ryan, Overbaugh, Julie, Matsen, Frederick A

“…Abstract Summary We present the phippery software suite for analyzing data from phage display methods that use immunoprecipitation and deep sequencing to…”
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Passively Acquired Constant Region 5–Specific Antibodies Associated With Improved Survival in Infants Who Acquire Human Immunodeficiency Virus by Yaffe, Zak A, Sung, Kevin, Bosire, Rose, Farquhar, Carey, Ngacha, Dorothy Mbori, Lohman-Payne, Barbara, Nduati, Ruth, John-Stewart, Grace, Matsen, Frederick A, Overbaugh, Julie

“…Abstract Studying vertical human immunodeficiency virus (HIV) transmission enables the impact of passively transferred antibodies on HIV transmission and…”
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Evaluating the Impact of Antibody Epitope and Function on HIV-1 Vertical Transmission by Yaffe, Zak A

“…Despite significant advances in scientific research and the advent of treatment and prevention strategies over the past several decades, the HIV/AIDS pandemic…”
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