Search Results - "Yaddanapudi, Madhavi Venkata"

Synthesis of a new series of quinoline/pyridine indole-3-sulfonamide hybrids as selective carbonic anhydrase IX inhibitors by Singh, Priti, Sridhar Goud, Nerella, Swain, Baijayantimala, Kumar Sahoo, Santosh, Choli, Abhishek, Angeli, Andrea, Singh Kushwah, Bhoopendra, Madhavi Yaddanapudi, Venkata, Supuran, Claudiu T., Arifuddin, Mohammed

“…In this manuscript, design, rational, synthesisand carbonic anhydrases (CAs) inhibitory profile of the quinoline/pyridine linked indole-3-sulfonamide…”
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Identification of nitrofuranylchalcone tethered benzoxazole-2-amines as potent inhibitors of drug resistant Mycobacterium tuberculosis demonstrating bactericidal efficacy by Kumar Sahoo, Santosh, Maddipatla, Sarvan, Nageswara Rao Gajula, Siva, Naiyaz Ahmad, Mohammad, Kaul, Grace, Nanduri, Srinivas, Sonti, Rajesh, Dasgupta, Arunava, Chopra, Sidharth, Madhavi Yaddanapudi, Venkata

“…[Display omitted] •New benzoxazole-2-amine linked chalcone hybrids were developed.•Antimycobacterial and antibacterial screening indicated selectivity towards…”
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Exploration of Isoxazole‐Carboxylic Acid Methyl Ester Based 2‐Substituted Quinoline Derivatives as Promising Antitubercular Agents by Kumar Sahoo, Santosh, Naiyaz Ahmad, Mohammad, Kaul, Grace, Nanduri, Srinivas, Dasgupta, Arunava, Chopra, Sidharth, Madhavi Yaddanapudi, Venkata

“…In pursuit of potent anti‐TB agents active against drug resistant tuberculosis (DR‐TB), herein we report synthesis and bio‐evaluation of a new series of…”
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Synthesis and biological evaluation of new 3-substituted coumarin derivatives as selective inhibitors of human carbonic anhydrase IX and XII by Mahammad Ghouse, Shaik, Bahatam, Kavyaraj, Angeli, Andrea, Pawar, Gaurav, Chinchilli, Krishna Kartheek, Yaddanapudi, Venkata Madhavi, Mohammed, Arifuddin, Supuran, Claudiu T., Nanduri, Srinivas

“…The Carbonic anhydrase isoforms IX and XII play a significant role in regulating the intracellular and extracellular pH in hypoxic tumours abetting the…”
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Design, Synthesis and Biological Assessment of Rhodanine-Linked Benzenesulfonamide Derivatives as Selective and Potent Human Carbonic Anhydrase Inhibitors by Swain, Baijayantimala, Khan, Abrar, Singh, Priti, Marde, Vaibhav S, Angeli, Andrea, Chinchilli, Krishna Kartheek, Yaddanapudi, Venkata Madhavi, Carradori, Simone, Supuran, Claudiu T, Arifuddin, Mohammed

“…A novel series of twenty-five rhodamine-linked benzenesulfonamide derivatives ( - and - ) were synthesized and screened for their inhibitory action against…”
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Microwave‐Assisted Copper‐Catalyzed One‐Pot Synthesis of 2‐Aryl/Heteroaryl‐4‐Quinolones via Sequential Intramolecular Aza‐Michael Addition and Oxidation by Singh, Priti, Kumar Sahoo, Santosh, Sridhar Goud, Nerella, Swain, Baijayantimala, Madhavi Yaddanapudi, Venkata, Arifuddin, Mohammed

“…A protocol has been developed that allows the synthesis of 2‐aryl/heteroaryl‐4‐quinolones from readily available, affordable starting materials. The reaction…”
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Ureidosulfocoumarin Derivatives As Selective and Potent Carbonic Anhydrase IX and XII Inhibitors by Singh, Priti, Kumar Sigalapalli, Dilep, Sridhar Goud, Nerella, Swain, Baijayantimala, Kumar Sahoo, Santosh, Angeli, Andrea, Shaik, Afzal B., Madhavi Yaddanapudi, Venkata, Supuran, Claudiu T., Arifuddin, Mohammed

“…Owing to severe allergic reactions (anaphylaxis) and resistance exhibited by sulfonamide‐based carbonic anhydrase (CA) inhibitors, non‐classical or…”
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Bacterial Pyruvate Kinase: A New Potential Target to Combat Drug‐Resistant Staphylococcus aureus Infections by Akunuri, Ravikumar, Unnissa, Tanveer, Vadakattu, Manasa, Bujji, Sushmitha, Mahammad Ghouse, Shaik, Madhavi Yaddanapudi, Venkata, Chopra, Sidharth, Nanduri, Srinivas

“…Severity of Infections caused by Staphylococcus aureus ranges from trivial to spine chilling. Irrespective of multiple drugs availability to treat S. aureus…”
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Benzyl/phenyl‐1,2,3‐Triazole Tethered 3‐Acetyl Coumarins as Potential Drug‐Resistant Antitubercular Agents: Synthesis, Biology, and in Silico Investigations as Mtb DNA Gyrase Inhibitors by Bakchi, Bulti, Maddipatla, Sarvan, Gottemukkala, Seshamma, Raut, Shital, Naiyaz Ahmad, Mohammad, Imran, Mohmmad, Saxena, Deepanshi, Maitra, Rahul, Kumari Agnivesh, Puja, Pal Kalia, Nitin, Nanduri, Srinivas, Dasgupta, Arunava, Chopra, Sidharth, Madhavi Yaddanapudi, Venkata

“…Owing to the emergence of multi‐drug resistant tuberculosis, there is a need for the exploration of new antitubercular agents. In this context, new…”
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Identification of 1,3‐Substituted Pyrazole‐Based Carboxamide Derivatives as Potent Antitubercular Agents by Baliram Gaikwad, Nikhil, Kumar Sahoo, Santosh, Ommi, Ojaswitha, Naiyaz Ahmad, Mohammad, Pathan, Afroz, Kaul, Grace, Nanduri, Srinivas, Dasgupta, Arunava, Chopra, Sidharth, Madhavi Yaddanapudi, Venkata

“…In recent past, repurposing and subsequent medicinal chemistry efforts on anti‐obesity drug rimonabant has successfully delivered several pyrroles and…”
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Design, synthesis, and biological evaluation of N-(4-substituted)-3-phenylisoxazolo[5,4–d]pyrimidin-4-amine derivatives as apoptosis-inducing cytotoxic agents by Gaikwad, Nikhil Baliram, Bansod, Sapana, Mara, Alekhya, Garise, Ramana, Srinivas, Nanduri, Godugu, Chandraiah, Yaddanapudi, Venkata Madhavi

“…[Display omitted] •All the 28 derivatives synthesized were evaluated on the NCI-60-cell line panel.•Compound 10 h was the most potent derivative with the IC50…”
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A Microwave-Assisted SmI2‑Catalyzed Direct N‑Alkylation of Anilines with Alcohols by Gour, Jitendra, Gatadi, Srikanth, Malasala, Satyaveni, Yaddanpudi, Madhavi Venkata, Nanduri, Srinivas

“…A new protocol for the alkylation of aromatic amines has been described using alcohols in the presence of SmI2 as a catalyst with the generation of water as…”
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Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases by Swain, Baijayantimala, Sahoo, Santosh Kumar, Singh, Priti, Angeli, Andrea, Yaddanapudi, Venkata Madhavi, Supuran, Claudiu T., Arifuddin, Mohammed

“…A novel series of 32 sulfonamide containing quinolines (5a-j, 7a-k and 9a-k) were synthesized using tail approach and assayed for their carbonic anhydrase…”
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Synthesis and structure-activity relationship of new chalcone linked 5-phenyl-3-isoxazolecarboxylic acid methyl esters potentially active against drug resistant Mycobacterium tuberculosis by Sahoo, Santosh Kumar, Rani, Bandela, Gaikwad, Nikhil Baliram, Ahmad, Mohammad Naiyaz, Kaul, Grace, Shukla, Manjulika, Nanduri, Srinivas, Dasgupta, Arunava, Chopra, Sidharth, Yaddanapudi, Venkata Madhavi

“…In search of novel therapeutic agents active against emerging drug-resistant Mycobacterium tuberculosis and to counter the long treatment protocol of existing…”
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Exploration of 1,3,5-trisubstituted pyrazoline derivatives as human carbonic anhydrase inhibitors: Synthesis, biological evaluation and in silico studies by Srikanth, Danaboina, Shanthi, Kollu, Paoletti, Niccolò, Joshi, Swanand Vinayak, Shaik, Mahammad Ghouse, Rana, Preeti, Vadakattu, Manasa, Yaddanapudi, Venkata Madhavi, Supuran, Claudiu T., Nanduri, Srinivas

“…The human carbonic anhydrase (hCA) IX and XII isoforms are overexpressed in hypoxic conditions, contributing to cancer. Lack of isoform selectivity has been…”
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Synthetic Approaches toward Dabigatran Etexilate, an Oral Anticoagulant Drug by Kalam, Abdul, Mahammad Ghouse, Shaik, Joshi, Swanand Vinayak, Tamang, Nitesh, Sahu, Nived Rajesh, Yaddanapudi, Madhavi Venkata, Nanduri, Srinivas

“…Thromboembolic disorders affect millions of people worldwide. Anticoagulant drugs, such as Dabigatran etexilate, Rivaroxaban, Argatroban, Enoxaparin, and…”
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Small molecule inhibitors of NLRP3 inflammasome and GSK-3β in the management of traumatic brain injury: A review by Shaik, Mahammad Ghouse, Joshi, Swanand Vinayak, Akunuri, Ravikumar, Rana, Preeti, Rahman, Ziaur, Polomoni, Anusha, Yaddanapudi, Venkata Madhavi, Dandekar, Manoj P, Srinivas, Nanduri

“…Traumatic brain injury (TBI) is a debilitating mental condition which causes physical disability and morbidity worldwide. TBI may damage the brain by direct…”
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Exploration of quinoxaline-benzimidazole hybrids as apoptosis-inducing agents and tubulin polymerisation inhibitors by Ommi, Ojaswitha, Chilvery, Shrilekha, Dhopat, Priyanka Sudhir, Sharma, Anamika, Bhalerao, Harshada Anil, Dannaram, Srinivas Reddy, Nanduri, Srinivas, Sonti, Rajesh, Godugu, Chandraiah, Yaddanapudi, Venkata Madhavi

“…•New quinoxaline-benzimidazole hybrids were synthesized and evaluated against human cancer cell lines.•Compound 5l displayed excellent cytotoxicity towards…”
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New Indole‐based Phenylthiazolyl‐2,4‐dihydropyrazolones as Tubulin polymerization inhibitors: Multicomponent synthesis, cytotoxicity evaluation, and in silico studies by Bakchi, Bulti, Devabattula, Geetanjali, Maddipatla, Sarvan, Singampalli, Anuradha, Porna, Dileep Kumar, Nanduri, Srinivas, Sharma, Anamika, Godugu, Chandraiah, Yaddanapudi, Venkata Madhavi

“…A facile multicomponent synthesis of new indole‐based phenylthiazolyl‐dihydropyrazolone hybrids, their structural characterization, biological evaluation, and…”
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Efficient One-pot Synthesis of 3,3-di(indolyl)indolin-2-ones from Isatin and Indole Catalyzed by VOSO 4 as Non-Sulfonamide Carbonic Anhydrase Inhibitors by Swain, Baijayantimala, Singh, Priti, Angeli, Andrea, Sahoo, Santosh Kumar, Yaddanapudi, Venkata Madhavi, T Supuran, Claudiu, Arifuddin, Mohammed

“…A high yielding green protocol has been developed and delineated for the synthesis of 3,3- di(indolyl)indolin-2-ones, potentially bioactive compounds,…”
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