Search Results - "Yadawa, Arun Kumar"
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Revealing the Novel Role of Purinergic Receptor P2X4 in Phagocytic Uptake After Ischemic Stroke
Published in Journal of the American Heart Association (01-10-2024)“…Purinergic receptor P2X4 (P2X4R), highly expressed on microglia and macrophages, is activated by ATP released from damaged cells and linked to poststroke…”
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Exploring the therapeutic potential of sγPNA-141: Pharmacodynamics and mechanistic insights during ischemic stroke recovery
Published in Molecular therapy. Nucleic acids (10-12-2024)“…MicroRNA-141-3p plays a detrimental role in the pathology of ischemic stroke, presenting a new target for stroke treatment. This study introduces and validates…”
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Promising Polyphenols in Parkinson’s Disease Therapeutics
Published in Neurochemical research (01-08-2020)“…Parkinson’s disease (PD) is a slow progressive, second most common neurodegenerative disease characterized by the loss of dopaminergic neurons from the…”
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Curcumin protects against aging-related stress and dysfunction through autophagy activation in rat brain
Published in Molecular biology reports (01-12-2024)“…Background Curcumin ( Curcuma longa ) is a well-known medicinal plant that induces autophagy in various model species, helping maintain cellular homeostasis…”
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Mechanism for antiParkinsonian effect of resveratrol: Involvement of transporters, synaptic proteins, dendrite arborization, biochemical alterations, ER stress and apoptosis
Published in Food and chemical toxicology (01-09-2021)“…The present study was undertaken to evaluate the mechanism for antiParkinsonian effect of resveratrol employing 6-hydroxydopamine (6-OHDA) induced experimental…”
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Hyperglycemia and high nitric oxide level induced oxidative stress in the brain and molecular alteration in the neurons and glial cells of laboratory mouse, Mus musculus
Published in Neurochemistry international (01-03-2017)“…Chronic hyperglycemia (glucotoxicity) is reported to have detrimental effects on various brain functions leading to neurodegenerative changes. However, the…”
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Expression of stress hormones AVP and CRH in the hypothalamus of Mus musculus following water and food deprivation
Published in General and comparative endocrinology (01-12-2016)“…Highlights • Effect of water and food deprivation were studied in Mus musculus. • During water deprivation Expression of AVP is upregulated while expression of…”
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Berberine attenuates brain aging via stabilizing redox homeostasis and inflammation in an accelerated senescence model of Wistar rats
Published in Metabolic brain disease (01-06-2024)“…Aging is a multifaceted and progressive physiological change of the organism categorized by the accumulation of deteriorating processes, which ultimately…”
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Acarbose, an α-Glucosidase Inhibitor, Maintains Altered Redox Homeostasis During Aging by Targeting Glucose Metabolism in Rat Erythrocytes
Published in Rejuvenation research (01-02-2023)“…Increasing age is the single largest risk factor for a variety of chronic illnesses. As a result, improving the capability to target the aging process leads to…”
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Acarbose Mitigates Age-Dependent Alterations in Erythrocyte Membrane Transporters During Aging in Rats
Published in Rejuvenation research (01-08-2023)“…Acarbose (ACA), a well-studied and effective inhibitor of α-amylase and α-glucosidase, is a postprandial-acting antidiabetic medicine. The membrane of the…”
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Berberine may provide redox homeostasis during aging in rats
Published in Zeitschrift für Naturforschung C. A journal of biosciences (26-07-2023)“…Aging is a natural phenomenon, which is characterised by progressive physiological changes at cellular and organ level. During aging, the defence mechanism of…”
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Herbicide Paraquat provokes the stress responses of HPA axis of laboratory mouse, Mus musculus
Published in Pesticide biochemistry and physiology (01-01-2019)“…Paraquat (PQ) is a herbicide and well characterized pneumotoxicant which is also known to induce neurodegeneration in organisms. Aim of this study was to…”
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