Search Results - "Yadav, Vijesh Kumar"

Collagen 1A1 (COL1A1) Is a Reliable Biomarker and Putative Therapeutic Target for Hepatocellular Carcinogenesis and Metastasis by Ma, Hon-Ping, Chang, Hang-Lung, Bamodu, Oluwaseun Adebayo, Yadav, Vijesh Kumar, Huang, Ting-Yi, Wu, Alexander T H, Yeh, Chi-Tai, Tsai, Shin-Han, Lee, Wei-Hwa

“…Increasing evidence shows that hepatocellular carcinoma (HCC) is a principal cause of cancer-related mortality globally, especially among Asian and African…”
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NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation by Su, I-Chang, Su, Yu-Kai, Setiawan, Syahru Agung, Yadav, Vijesh Kumar, Fong, Iat-Hang, Yeh, Chi-Tai, Lin, Chien-Min, Liu, Heng-Wei

“…Glioblastoma multiforme (GBM) is a highly heterogeneous disease with a mesenchymal subtype tending to exhibit more aggressive and multitherapy-resistant…”
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PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway by Pai, Shin, Yadav, Vijesh Kumar, Kuo, Kuang-Tai, Pikatan, Narpati Wesa, Lin, Chun-Shu, Chien, Ming-Hsien, Lee, Wei-Hwa, Hsiao, Michael, Chiu, Shao-Chih, Yeh, Chi-Tai, Tsai, Jo-Ting

“…: Oral squamous cell carcinoma (OSCC) has a high prevalence and predicted global mortality rate of 67.1%, necessitating better therapeutic strategies…”
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The E3 Ubiquitin Ligase NEDD4-1 Mediates Temozolomide-Resistant Glioblastoma through PTEN Attenuation and Redox Imbalance in Nrf2-HO-1 Axis by Chuang, Hao-Yu, Hsu, Li-Yun, Pan, Chih-Ming, Pikatan, Narpati Wesa, Yadav, Vijesh Kumar, Fong, Iat-Hang, Chen, Chao-Hsuan, Yeh, Chi-Tai, Chiu, Shao-Chih

“…Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. It is highly resistant to chemotherapy, and tumor recurrence is common. Neuronal…”
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Computational analysis for identification of the extracellular matrix molecules involved in endometrial cancer progression by Yadav, Vijesh Kumar, Lee, Tzong-Yi, Hsu, Justin Bo-Kai, Huang, Hsien-Da, Yang, Wei-Chung Vivian, Chang, Tzu-Hao

“…Recurrence and poorly differentiated (grade 3 and above) and atypical cell type endometrial cancer (EC) have poor prognosis outcome. The mechanisms and…”
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Novel NFκB Inhibitor SC75741 Mitigates Chondrocyte Degradation and Prevents Activated Fibroblast Transformation by Modulating miR-21/GDF-5/SOX5 Signaling by Weng, Pei-Wei, Yadav, Vijesh Kumar, Pikatan, Narpati Wesa, Fong, Iat-Hang, Lin, I-Hsin, Yeh, Chi-Tai, Lee, Wei-Hwa

“…Osteoarthritis (OA) is a common articular disease manifested by the destruction of cartilage and compromised chondrogenesis in the aging population, with…”
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In-Silico Evaluation of Genetic Alterations in Ovarian Carcinoma and Therapeutic Efficacy of NSC777201, as a Novel Multi-Target Agent for TTK, NEK2, and CDK1 by Khedkar, Harshita Nivrutti, Wang, Yu-Chi, Yadav, Vijesh Kumar, Srivastava, Prateeti, Lawal, Bashir, Mokgautsi, Ntlotlang, Sumitra, Maryam Rachmawati, Wu, Alexander T. H., Huang, Hsu-Shan

“…Ovarian cancer is often detected at the advanced stages at the time of initial diagnosis. Early-stage diagnosis is difficult due to its asymptomatic nature,…”
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Role of GDF15/MAPK14 Axis in Chondrocyte Senescence as a Novel Senomorphic Agent in Osteoarthritis by Weng, Pei-Wei, Pikatan, Narpati Wesa, Setiawan, Syahru Agung, Yadav, Vijesh Kumar, Fong, Iat-Hang, Hsu, Chia-Hung, Yeh, Chi-Tai, Lee, Wei-Hwa

“…Osteoarthritis (OA) is most prevalent in older individuals and exerts a heavy social and economic burden. However, an effective and noninvasive approach to OA…”
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PAICS/DYRK3 Multienzyme Interactions as Coregulators of Purinosome Formation and Metabolism on Radioresistance in Oral Squamous Cell Carcinoma by Huang, Chin-Sheng, Hsieh, Ming-Shou, Yadav, Vijesh Kumar, Wu, Yang-Che, Liu, Shao-Cheng, Yeh, Chi-Tai, Huang, Mao-Suan

“…Oral squamous cell carcinoma (OSCC) is a prevalent type of oral cancer. While therapeutic innovations have made strides, radioresistance persists as a…”
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4-Acetyl-Antroquinonol B Improves the Sensitization of Cetuximab on Both Kras Mutant and Wild Type Colorectal Cancer by Modulating the Expression of Ras/Raf/miR-193a-3p Signaling Axis by Chu, Yi Cheng, Tsai, Tung-Yao, Yadav, Vijesh Kumar, Deng, Li, Huang, Chun-Chih, Tzeng, Yew-Min, Yeh, Chi-Tai, Chen, Ming-Yao

“…The KRAS mutation is one of the leading driver mutations in colorectal cancer (CRC), and it is usually associated with poor prognosis and drug resistance…”
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HNMT Upregulation Induces Cancer Stem Cell Formation and Confers Protection against Oxidative Stress through Interaction with HER2 in Non-Small-Cell Lung Cancer by Kuo, Kuang-Tai, Lin, Cheng-Hsin, Wang, Chun-Hua, Pikatan, Narpati Wesa, Yadav, Vijesh Kumar, Fong, Iat-Hang, Yeh, Chi-Tai, Lee, Wei-Hwa, Huang, Wen-Chien

“…The treatment of non-small-cell lung cancer (NSCLC) involves platinum-based chemotherapy. It is typically accompanied by chemoresistance resulting from…”
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Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells by Tiong, Tung-Yu, Weng, Pei-Wei, Wang, Chun-Hua, Setiawan, Syahru Agung, Yadav, Vijesh Kumar, Pikatan, Narpati Wesa, Fong, Iat-Hang, Yeh, Chi-Tai, Hsu, Chia-Hung, Kuo, Kuang-Tai

“…Background: Lung cancer remains a leading cause of cancer-related death, with an annual global mortality rate of 18.4%. Despite advances in diagnostic and…”
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Furanocoumarin Notopterol: Inhibition of Hepatocellular Carcinogenesis through Suppression of Cancer Stemness Signaling and Induction of Oxidative Stress-Associated Cell Death by Huang, Ting-Yun, Yang, Ching-Kuo, Chen, Ming-Yao, Yadav, Vijesh Kumar, Fong, Iat-Hang, Yeh, Chi-Tai, Cherng, Yih-Giun

“…Hepatocellular carcinoma (HCC) remains an aggressive malignancy with a poor prognosis and a leading cause of cancer-related mortality globally. Cumulative…”
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Structure-based strategies for synthesis, lead optimization and biological evaluation of N-substituted anthra[1,2-c][1,2,5]thiadiazole-6,11-dione derivatives as potential multi-target anticancer agents by Ali, Ahmed Atef Ahmed, Lee, Yu-Ru, Wu, Alexander T.H., Yadav, Vijesh Kumar, Yu, Dah-Shyong, Huang, Hsu-Shan

“…[Display omitted] As part of our research on developing multi-target small molecule anticancer agents, we designed, synthesized, and biologically evaluated a…”
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Notopterol mitigates IL-1β-triggered pyroptosis by blocking NLRP3 inflammasome via the JAK2/NF-kB/hsa-miR-4282 route in osteoarthritis by Chen, Ko-Ta, Yeh, Chi-Tai, Yadav, Vijesh Kumar, Pikatan, Narpati Wesa, Fong, Iat-Hang, Lee, Wei-Hwa, Chiu, Yen-Shuo

“…Osteoarthritis (OA), the most prevalent form of arthritis, impacts approximately 10% of men and 18% of women aged above 60 years. Currently, a complete cure…”
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Pterostilbene Increases LDL Metabolism in HL-1 Cardiomyocytes by Modulating the PCSK9/HNF1α/SREBP2/LDLR Signaling Cascade, Upregulating Epigenetic hsa-miR-335 and hsa-miR-6825, and LDL Receptor Expression by Lin, Yen-Kuang, Yeh, Chi-Tai, Kuo, Kuang-Tai, Yadav, Vijesh Kumar, Fong, Iat-Hang, Kounis, Nicholas G., Hu, Patrick, Hung, Ming-Yow

“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) can promote the degradation of low-density lipoprotein (LDL) receptor (LDLR), leading to…”
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Tumor-Associated Macrophages Affect the Tumor Microenvironment and Radioresistance via the Upregulation of CXCL6/CXCR2 in Hepatocellular Carcinoma by Lee, Hsin-Lun, Tsai, Yi-Chieh, Pikatan, Narpati Wesa, Yeh, Chi-Tai, Yadav, Vijesh Kumar, Chen, Ming-Yao, Tsai, Jo-Ting

“…Hepatocellular carcinoma is the sixth most diagnosed malignancy and the fourth most common cause of cancer-related mortality globally. Despite progress in the…”
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Antrodia cinnamomea Enhances Chemo-Sensitivity of 5-FU and Suppresses Colon Tumorigenesis and Cancer Stemness via Up-Regulation of Tumor Suppressor miR-142-3p by Huang, Yan-Jiun, Yadav, Vijesh Kumar, Srivastava, Prateeti, Wu, Alexander Th, Huynh, Thanh-Tuan, Wei, Po-Li, Huang, Chi-Ying F, Huang, Tse-Hung

“…5-Fluorouracil (5-FU) regimen remains the backbone of the first-line agent to treat colon cancer, but often these patients develop resistance. Cancer stem…”
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Ubiquitin-Specific Protease 6 n-Terminal-like Protein (USP6NL) and the Epidermal Growth Factor Receptor (EGFR) Signaling Axis Regulates Ubiquitin-Mediated DNA Repair and Temozolomide-Resistance in Glioblastoma by Su, I-Chang, Su, Yu-Kai, Chuang, Hao-Yu, Yadav, Vijesh Kumar, Setiawan, Syahru Agung, Fong, Iat-Hang, Yeh, Chi-Tai, Huang, Hui-Chuan, Lin, Chien-Min

“…Glioblastoma multiforme (GBM) is the most malignant glioma, with a 30–60% epidermal growth factor receptor (EGFR) mutation. This mutation is associated with…”
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Abstract 13607: The Lipoprotein(a)-Induced Soluble CD36/Interleukin-6/RAS Homolog Family Member A-GTP Signaling Axis Promotes M1 Macrophage Polarization in Coronary Artery Spasm by Hung, Ming-Yow, Yeh, Chi-tai, Yadav, Vijesh Kumar, Fong, Iat-Hang

“…Abstract only Background: We previously demonstrated that lipoprotein(a) (Lp(a)) mediated coronary artery spasm (CAS) through α7-nAChR/p38 MAPK/IL-6/RhoA-GTP…”
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