Search Results - "Yabuki, Yukari"
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Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast
Published in Genetics (Austin) (01-05-2019)“…Reduced ribosome biogenesis in response to environmental conditions is a key feature of cell adaptation to stress. For example, ribosomal genes are…”
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Roles of Ebp2 and ribosomal protein L36 in ribosome biogenesis in Saccharomyces cerevisiae
Published in Current genetics (01-02-2015)“…Ebp2 plays an essential role in biogenesis of 60S ribosomal subunits. We determined the genetic interactions between EBP2 and RPL36A/B, which encodes ribosomal…”
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Oncologic outcomes and technical considerations of nipple-sparing mastectomies in breast cancer: experience of 425 cases from a single institution
Published in Breast cancer (Tokyo, Japan) (01-11-2016)“…Background Nipple-sparing mastectomy (NSM) is an advantageous treatment option, providing a complete cure and good cosmetic results. We tested whether NSM is a…”
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Arp2/3 complex and Mps3 are required for regulation of ribosome biosynthesis in the secretory stress response
Published in Yeast (Chichester, England) (01-04-2017)“…Secretory defects cause transcriptional repression of ribosome biogenesis in Saccharomyces cerevisiae. However, the molecular mechanism underlying secretory…”
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The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation
Published in The Journal of biological chemistry (04-05-2001)“…BRCA1-BARD1 constitutes a heterodimeric RING finger complex associated through its N-terminal regions. Here we demonstrate that the BRCA1-BARD1 heterodimeric…”
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SMY2 and SYH1 suppress defects in ribosome biogenesis caused by ebp2 mutations
Published in Bioscience, biotechnology, and biochemistry (02-09-2015)“…Ebp2 is an assembly factor of the 60S ribosomal subunit in yeast. We demonstrate that overexpression of SMY2 or SYH1 partially suppresses defects in growth and…”
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Glycogen synthase kinase-3 is involved in regulation of ribosome biogenesis in yeast
Published in Bioscience, biotechnology, and biochemistry (04-05-2014)“…Secretory defects cause transcriptional repression of both ribosomal proteins and ribosomal RNA genes in Saccharomyces cerevisiae. Rrs1, a trans-acting factor…”
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essential function of Rrs1 in ribosome biogenesis is conserved in budding and fission yeasts
Published in Yeast (Chichester, England) (01-09-2015)“…The Rrs1 protein plays an essential role in the biogenesis of 60S ribosomal subunits in budding yeast (Saccharomyces cerevisiae). Here, we examined whether the…”
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Sphingolipids regulate telomere clustering by affecting transcriptional levels of genes involved in telomere homeostasis
Published in Journal of cell science (01-01-2015)“…In eukaryotic organisms including mammals, nematodes, and yeasts, the ends of chromosomes, telomeres are clustered at the nuclear periphery. Telomere…”
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Positive predictive value for malignancy of pure flat epithelial atypia diagnosis by percutaneous needle biopsy of the breast: management of FEA in ultrasonography
Published in Breast cancer (Tokyo, Japan) (01-11-2015)“…Background Some reports suggest that the rate of definitive diagnosis of malignant tumors, namely, the final diagnosis being revised to a higher stage, in…”
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Radiologic-pathological correlation of punctate hyperechoic foci by ultrasound in stereotactic vacuum-assisted breast biopsy samples
Published in Japanese Journal of Radiology (01-12-2009)“…Purpose To correlate punctate hyperechoic foci (PHF) on ultrasound (US) with microcalcifications detected by mammography (MMG) and at histopathology. Materials…”
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Sphingolipids regulate telomere clustering by affecting the transcription of genes involved in telomere homeostasis
Published in Journal of cell science (15-07-2015)“…In eukaryotic organisms, including mammals, nematodes and yeasts, the ends of chromosomes, telomeres are clustered at the nuclear periphery. Telomere…”
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The essential function of Rrs1 in ribosome biogenesis is conserved in budding and fission yeasts: The ribosome biogenesis factor Rrs1
Published in Yeast (Chichester, England) (01-09-2015)Get full text
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Breast cancer
Published in Gan to kagaku ryoho (01-11-2002)“…In Japan the mortality and incidence rates of breast cancer have been increasing. In 2000, the number of breast cancer deaths in female was 9,171. In 1996, the…”
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A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats
Published in Cancer letters (20-02-2006)“…BARD1 is a crucial partner of the breast and ovarian tumor suppressor BRCA1 required for ubiquitin ligase activity and for reciprocal stabilization in cells…”
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