Search Results - "Yablonskiy, Dmitriy A."

Biophysical mechanisms of phase contrast in gradient echo MRI by He, Xiang, Yablonskiy, Dmitriy A

“…Recently reported contrast in phase images of human and animal brains obtained with gradient-recalled echo MRI holds great promise for the in vivo study of…”
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Separation of cellular and BOLD contributions to T2 signal relaxation by Ulrich, Xialing, Yablonskiy, Dmitriy A.

“…Purpose The development of a reliable clinical technique for quantitative measurements of the parameters defining the BOLD effect, i.e., oxygen extraction…”
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Quantitative BOLD: Mapping of human cerebral deoxygenated blood volume and oxygen extraction fraction: Default state by He, Xiang, Yablonskiy, Dmitriy A.

“…Since Ogawa et al. (Proc Natl Acad Sci USA 1990;87:9868–9872) made the fundamental discovery of blood oxygenation level‐dependent (BOLD) contrast in MRI, most…”
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On the role of neuronal magnetic susceptibility and structure symmetry on gradient echo MR signal formation by Sukstanskii, Alexander L., Yablonskiy, Dmitriy A.

“…Purpose Phase images obtained by gradient‐recalled echo (GRE) MRI provide new contrast in the brain that is distinct from that obtained with conventional…”
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Voxel spread function method for correction of magnetic field inhomogeneity effects in quantitative gradient-echo-based MRI by Yablonskiy, Dmitriy A., Sukstanskii, Alexander L., Luo, Jie, Wang, Xiaoqi

“…Purpose Macroscopic magnetic field inhomogeneities adversely affect different aspects of MRI images. In quantitative MRI when the goal is to quantify…”
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Blood oxygenation level-dependent (BOLD)-based techniques for the quantification of brain hemodynamic and metabolic properties - theoretical models and experimental approaches by Yablonskiy, Dmitriy A., Sukstanskii, Alexander L., He, Xiang

“…The quantitative evaluation of brain hemodynamics and metabolism, particularly the relationship between brain function and oxygen utilization, is important for…”
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In vivo evaluation of heme and non-heme iron content and neuronal density in human basal ganglia by Yablonskiy, Dmitriy A, Wen, Jie, Kothapalli, Satya V.V.N., Sukstanskii, Alexander L

“…Non-heme iron is an important element supporting the structure and functioning of biological tissues. Imbalance in non-heme iron can lead to different…”
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Theoretical models of the diffusion weighted MR signal by Yablonskiy, Dmitriy A., Sukstanskii, Alexander L.

“…Diffusion MRI plays a very important role in studying biological tissue structure and functioning both in health and disease. Proper interpretation of…”
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Quantitative gradient recalled echo (qGRE) MRI enables in vivo measurement of pre-atrophic neurodegeneration in a mouse model of Alzheimer's disease by Tomaszewski, Michal R., Sukstanskii, Alexander L., Haley, Hyking, Meng, Xiangjun, Miller, Corin O., Yablonskiy, Dmitriy A.

“…•There is an unmet need for a non-invasive neurodegeneration measurement method in preclinical AD models.•Novel MRI approach allows capturing of neuronal loss…”
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Validation of oxygen extraction fraction measurement by qBOLD technique by He, Xiang, Zhu, Mingming, Yablonskiy, Dmitriy A.

“…Measurement of brain tissue oxygen extraction fraction (OEF) in both baseline and functionally activated states can provide important information on brain…”
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Biophysical mechanisms of MRI signal frequency contrast in multiple sclerosis by Yablonskiy, Dmitriy A, Luo, Jie, Sukstanskii, Alexander L, Iyer, Aditi, Cross, Anne H

“…Phase images obtained with gradient echo MRI provide image contrast distinct from T1- and T2-weighted images. It is commonly assumed that the local…”
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Deep learning‐based Accelerated and Noise‐Suppressed Estimation (DANSE) of quantitative Gradient‐Recalled Echo (qGRE) magnetic resonance imaging metrics associated with human brain neuronal structure and hemodynamic properties by Kahali, Sayan, Kothapalli, Satya V. V. N., Xu, Xiaojian, Kamilov, Ulugbek S., Yablonskiy, Dmitriy A.

“…The purpose of the current study was to introduce a Deep learning‐based Accelerated and Noise‐Suppressed Estimation (DANSE) method for reconstructing…”
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Limbic system damage in MS: MRI assessment and correlations with clinical testing by Wen, Jie, Yablonskiy, Dmitriy A, Salter, Amber, Cross, Anne H

“…Volume loss in some limbic region structures has been observed in multiple sclerosis (MS) patients. However, in vivo evaluation of existing tissue cellular…”
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Experimental evidence of age-related adaptive changes in human acinar airways by Quirk, James D, Sukstanskii, Alexander L, Woods, Jason C, Lutey, Barbara A, Conradi, Mark S, Gierada, David S, Yusen, Roger D, Castro, Mario, Yablonskiy, Dmitriy A

“…The progressive decline of lung function with aging is associated with changes in lung structure at all levels, from conducting airways to acinar airways…”
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The Role of the Human Brain Neuron-Glia-Synapse Composition in Forming Resting-State Functional Connectivity Networks by Kahali, Sayan, Raichle, Marcus E, Yablonskiy, Dmitriy A

“…While significant progress has been achieved in studying resting-state functional networks in a healthy human brain and in a wide range of clinical conditions,…”
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Theoretical Model of Temperature Regulation in the Brain during Changes in Functional Activity by Sukstanskii, Alexander L., Yablonskiy, Dmitriy A.

“…The balance between metabolic heat production, heat removal by blood flow, and heat conductance defines local temperature distribution in a living tissue…”
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Statistical model for diffusion attenuated MR signal by Yablonskiy, Dmitriy A., Bretthorst, G. Larry, Ackerman, Joseph J.H.

“…A general statistical model that can describe a rather large number of experimental results related to the structure of the diffusion‐attenuated MR signal in…”
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Stronger Microstructural Damage Revealed in Multiple Sclerosis Lesions With Central Vein Sign by Quantitative Gradient Echo MRI by Levasseur, Victoria A., Xiang, Biao, Salter, Amber, Yablonskiy, Dmitriy A., Cross, Anne H.

“…Background Multiple sclerosis (MS) lesions typically form around a central vein that can be visualized with FLAIR* MRI, creating the central vein sign (CVS)…”
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On the nature of the NAA diffusion attenuated MR signal in the central nervous system by Kroenke, Christopher D., Ackerman, Joseph J.H., Yablonskiy, Dmitriy A.

“…In the brain, on a macroscopic scale, diffusion of the intraneuronal constituent N‐acetyl‐L‐aspartate (NAA) appears to be isotropic. In contrast, on a…”
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Evaluating brain damage in multiple sclerosis with simultaneous multi‐angular‐relaxometry of tissue by Xiang, Biao, Wen, Jie, Schmidt, Robert E., Sukstanskii, Alexander L., Mamah, Daniel, Yablonskiy, Dmitriy A., Cross, Anne H.

“…Objective Multiple sclerosis (MS) is a common demyelinating central nervous system disease. MRI methods that can quantify myelin loss are needed for trials of…”
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