Search Results - "Yab, Tracy C."

Hepatocellular Carcinoma Detection by Plasma Methylated DNA: Discovery, Phase I Pilot, and Phase II Clinical Validation by Kisiel, John B., Dukek, Brian A., V.S.R. Kanipakam, Reddappa, Ghoz, Hassan M., Yab, Tracy C., Berger, Calise K., Taylor, William R., Foote, Patrick H., Giama, Nasra H., Onyirioha, Kristeen, Abdallah, Mohamed A., Burger, Kelli N., Slettedahl, Seth W., Mahoney, Douglas W., Smyrk, Thomas C., Lewis, Jason T., Giakoumopoulos, Maria, Allawi, Hatim T., Lidgard, Graham P., Roberts, Lewis R., Ahlquist, David A.

“…Early detection improves hepatocellular carcinoma (HCC) outcomes, but better noninvasive surveillance tools are needed. We aimed to identify and validate…”
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New DNA Methylation Markers for Pancreatic Cancer: Discovery, Tissue Validation, and Pilot Testing in Pancreatic Juice by Kisiel, John B, Raimondo, Massimo, Taylor, William R, Yab, Tracy C, Mahoney, Douglas W, Sun, Zhifu, Middha, Sumit, Baheti, Saurabh, Zou, Hongzhi, Smyrk, Thomas C, Boardman, Lisa A, Petersen, Gloria M, Ahlquist, David A

“…Discriminant markers for pancreatic cancer detection are needed. We sought to identify and validate methylated DNA markers for pancreatic cancer using…”
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Next-Generation Stool DNA Test Accurately Detects Colorectal Cancer and Large Adenomas by Ahlquist, David A, Zou, Hongzhi, Domanico, Michael, Mahoney, Douglas W, Yab, Tracy C, Taylor, William R, Butz, Malinda L, Thibodeau, Stephen N, Rabeneck, Linda, Paszat, Lawrence F, Kinzler, Kenneth W, Vogelstein, Bert, Bjerregaard, Niels Chr, Laurberg, Søren, Sørensen, Henrik Toft, Berger, Barry M, Lidgard, Graham P

“…Background & Aims Technical advances have led to stool DNA (sDNA) tests that might accurately detect neoplasms on both sides of the colorectum. We assessed…”
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Highly Discriminant Methylated DNA Markers for the Non-endoscopic Detection of Barrett's Esophagus by Iyer, Prasad G, Taylor, William R, Johnson, Michele L, Lansing, Ramona L, Maixner, Kristyn A, Yab, Tracy C, Simonson, Julie A, Devens, Mary E, Slettedahl, Seth W, Mahoney, Douglas W, Berger, Calise K, Foote, Patrick H, Smyrk, Thomas C, Wang, Kenneth K, Wolfsen, Herbert C, Ahlquist, David A

“…Minimally invasive methods have been described to detect Barrett's esophagus (BE), but are limited by subjectivity and suboptimal accuracy. We identified…”
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Stool DNA Testing for Screening Detection of Colorectal Neoplasia in Alaska Native People by Redwood, Diana G., PhD, Asay, Elvin D., MS, Blake, Ian D., MS, Sacco, Pamela E., RN, Christensen, Claudia M., ANP, Sacco, Frank D., MD, Tiesinga, James J., MD, Devens, Mary E., BA, Alberts, Steven R., MD, Mahoney, Douglas W., MS, Yab, Tracy C., BS, Foote, Patrick H., MD, Smyrk, Thomas C., MD, Provost, Ellen M., DO, Ahlquist, David A., MD

“…Abstract Objective To assess the accuracy of a multitarget stool DNA test (MT-sDNA) compared with fecal immunochemical testing for hemoglobin (FIT) for…”
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A Comprehensive Approach to Sequence-oriented IsomiR annotation (CASMIR): demonstration with IsomiR profiling in colorectal neoplasia by Wu, Chung Wah, Evans, Jared M, Huang, Shengbing, Mahoney, Douglas W, Dukek, Brian A, Taylor, William R, Yab, Tracy C, Smyrk, Thomas C, Jen, Jin, Kisiel, John B, Ahlquist, David A

“…MicroRNA (miRNA) profiling is an important step in studying biological associations and identifying marker candidates. miRNA exists in isoforms, called…”
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Novel Approach to Fecal Occult Blood Testing by Assay of Erythrocyte-Specific microRNA Markers by Wu, Chung Wah, Cao, Xiaoming, Berger, Calise K., Foote, Patrick H., Mahoney, Douglas W., Simonson, Julie A., Anderson, Bradley W., Yab, Tracy C., Taylor, William R., Boardman, Lisa A., Kisiel, John B., Ahlquist, David A.

“…Background Fecal occult blood testing (FOBT) has historically relied on methods to detect hemoglobin with no fundamental innovations in decades. Aim To examine…”
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Detection of colorectal serrated polyps by stool DNA testing: comparison with fecal immunochemical testing for occult blood (FIT) by Heigh, Russell I, Yab, Tracy C, Taylor, William R, Hussain, Fareeda T N, Smyrk, Thomas C, Mahoney, Douglas W, Domanico, Michael J, Berger, Barry M, Lidgard, Graham P, Ahlquist, David A

“…Precursors to 1/3 of colorectal cancer (CRC), serrated polyps have been under-detected by screening due to their inconspicuous, non-hemorrhagic, and proximal…”
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DNA Methylation Markers for Detection of Cholangiocarcinoma: Discovery, Validation, and Clinical Testing in Biliary Brushings and Plasma by Yang, Ju Dong, Ghoz, Hassan, Aboelsoud, Mohammed M., Taylor, William R., Yab, Tracy C., Berger, Calise K., Cao, Xiaoming, Foote, Patrick H., Giama, Nasra H., Barr Fritcher, Emily G., Mahoney, Douglas W., Moser, Catherine D., Smyrk, Thomas C., Kipp, Benjamin R., Gores, Gregory J., Roberts, Lewis R., Kisiel, John B.

“…Cholangiocarcinoma (CCA) has poor prognosis due to late‐stage, symptomatic presentation. Altered DNA methylation markers may improve diagnosis of CCA…”
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Shifts in the Fecal Microbiota Associated with Adenomatous Polyps by Hale, Vanessa L, Chen, Jun, Johnson, Stephen, Harrington, Sean C, Yab, Tracy C, Smyrk, Thomas C, Nelson, Heidi, Boardman, Lisa A, Druliner, Brooke R, Levin, Theodore R, Rex, Douglas K, Ahnen, Dennis J, Lance, Peter, Ahlquist, David A, Chia, Nicholas

“…Adenomatous polyps are the most common precursor to colorectal cancer, the second leading cause of cancer-related death in the United States. We sought to…”
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Stool DNA testing for the detection of pancreatic cancer by Kisiel, John B., Yab, Tracy C., Taylor, William R., Chari, Suresh T., Petersen, Gloria M., Mahoney, Douglas W., Ahlquist, David A.

“…BACKGROUND: Pancreatic cancer (PanC) presents at late stage with high mortality. Effective early detection methods are needed. Aberrantly methylated genes are…”
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Discovery, Validation, and Application of Novel Methylated DNA Markers for Detection of Esophageal Cancer in Plasma by Qin, Yi, Wu, Chung W, Taylor, William R, Sawas, Tarek, Burger, Kelli N, Mahoney, Douglas W, Sun, Zhifu, Yab, Tracy C, Lidgard, Graham P, Allawi, Hatim T, Buttar, Navtej S, Smyrk, Thomas C, Iyer, Prasad G, Katzka, David A, Ahlquist, David A, Kisiel, John B

“…The burden of esophageal cancer continues to rise, and noninvasive screening tools are needed. Methylated DNA markers (MDM) assayed from plasma show promise in…”
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Analysis of DNA Methylation at Specific Loci in Stool Samples Detects Colorectal Cancer and High-Grade Dysplasia in Patients With Inflammatory Bowel Disease by Kisiel, John B., Klepp, Pasquale, Allawi, Hatim T., Taylor, William R., Giakoumopoulos, Maria, Sander, Tamara, Yab, Tracy C., Moum, Bjorn A., Lidgard, Graham P., Brackmann, Stephan, Mahoney, Douglas W., Roseth, Arne, Ahlquist, David A.

“…Patients with inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn’s disease, are at increased risk for colorectal cancer (CRC). Analyses…”
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Detection of Gastric Cancer with Novel Methylated DNA Markers: Discovery, Tissue Validation, and Pilot Testing in Plasma by Anderson, Bradley W, Suh, Yun-Suhk, Choi, Boram, Lee, Hyuk-Joon, Yab, Tracy C, Taylor, William R, Dukek, Brian A, Berger, Calise K, Cao, Xiaoming, Foote, Patrick H, Devens, Mary E, Boardman, Lisa A, Kisiel, John B, Mahoney, Douglas W, Slettedahl, Seth W, Allawi, Hatim T, Lidgard, Graham P, Smyrk, Thomas C, Yang, Han-Kwang, Ahlquist, David A

“…Gastric adenocarcinoma is the third most common cause of cancer mortality worldwide. Accurate and affordable noninvasive detection methods have potential value…”
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Stool DNA Testing for the Detection of Pancreatic Cancer: Assessment of Methylation Marker Candidates by KISIEL, John B, YAB, Tracy C, TAYLOR, William R, CHARI, Suresh T, PETERSEN, Gloria M, MAHONEY, Douglas W, AHLQUIST, David A

“…Pancreatic cancer (PanC) presents at late stage with high mortality. Effective early detection methods are needed. Aberrantly methylated genes are unexplored…”
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Methylated DNA in Pancreatic Juice Distinguishes Patients With Pancreatic Cancer From Controls by Majumder, Shounak, Raimondo, Massimo, Taylor, William R., Yab, Tracy C., Berger, Calise K., Dukek, Brian A., Cao, Xiaoming, Foote, Patrick H., Wu, Chung Wah, Devens, Mary E., Mahoney, Douglas W., Smyrk, Thomas C., Pannala, Rahul, Chari, Suresh T., Vege, Santhi Swaroop, Topazian, Mark D., Petersen, Bret T., Levy, Michael J., Rajan, Elizabeth, Gleeson, Ferga C., Abu Dayyeh, Barham, Nguyen, Cuong C., Faigel, Douglas O., Woodward, Timothy A., Wallace, Michael B., Petersen, Gloria, Allawi, Hatim T., Lidgard, Graham P., Kisiel, John B., Ahlquist, David A.

“…Precursors of pancreatic cancer arise in the ductal epithelium; markers exfoliated into pancreatic juice might be used to detect high-grade dysplasia (HGD) and…”
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Clinical Performance of an Automated Stool DNA Assay for Detection of Colorectal Neoplasia by Lidgard, Graham P, Domanico, Michael J, Bruinsma, Janelle J, Light, James, Gagrat, Zubin D, Oldham–Haltom, Rebecca L, Fourrier, Keith D, Allawi, Hatim, Yab, Tracy C, Taylor, William R, Simonson, Julie A, Devens, Mary, Heigh, Russell I, Ahlquist, David A, Berger, Barry M

“…Background & Aims Colorectal cancer (CRC) and advanced precancers can be detected noninvasively by analyses of exfoliated DNA markers and hemoglobin in stool…”
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Novel Methylated DNA Markers Discriminate Advanced Neoplasia in Pancreatic Cysts: Marker Discovery, Tissue Validation, and Cyst Fluid Testing by Majumder, Shounak, Taylor, William R, Yab, Tracy C, Berger, Calise K, Dukek, Brian A, Cao, Xiaoming, Foote, Patrick H, Wu, Chung Wah, Mahoney, Douglas W, Aslanian, Harry R, Fernández-Del Castillo, Carlos, Doyle, Leona A, Farrell, James J, Fisher, William E, Lee, Linda S, Lee, Yvonne N, Park, Walter, Rodrigues, Clifton, Gould Rothberg, Bonnie Elyssa, Salem, Ronald R, Simeone, Diane M, Urs, Sumithra, Van Buren, George, Smyrk, Thomas C, Allawi, Hatim T, Lidgard, Graham P, Raimondo, Massimo, Chari, Suresh T, Kendrick, Michael L, Kisiel, John B, Topazian, Mark D, Ahlquist, David A

“…Pancreatic cystic lesions (PCLs) may be precancerous. Those likely to harbor high-grade dysplasia (HGD) or pancreatic cancer (PC) are targets for surgical…”
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Accurate Nonendoscopic Detection of Barrett's Esophagus by Methylated DNA Markers: A Multisite Case Control Study by Iyer, Prasad G., Taylor, William R., Johnson, Michele L., Lansing, Ramona L., Maixner, Kristyn A., Hemminger, Lois L., Cayer, Frances K., Yab, Tracy C., Devens, Mary E., Slettedahl, Seth W., Broderick, Brendan T., Mahoney, Douglas W., McGlinch, Maria C., Berger, Calise K., Foote, Patrick H., Giakomopoulos, Maria, Allawi, Hatim, Smyrk, Thomas C., Wang, Kenneth K., Katzka, David A., Wolfsen, Herbert C., Burke, James A., Ahlquist, David A., Kisiel, John B.

“…Nonendoscopic Barrett's esophagus (BE) screening may help improve esophageal adenocarcinoma outcomes. We previously demonstrated promising accuracy of…”
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DNA Methylation and Mutation of Small Colonic Neoplasms in Ulcerative Colitis and Crohn's Colitis: Implications for Surveillance by Johnson, David H, Taylor, William R, Aboelsoud, Mohammed M, Foote, Patrick H, Yab, Tracy C, Cao, Xiaoming, Smyrk, Thomas C, Loftus, Jr, Edward V, Mahoney, Douglas W, Ahlquist, David A, Kisiel, John B

“…Stool DNA testing in patients with inflammatory bowel disease (IBD) may detect colorectal cancer and advanced precancers with high sensitivity; less is known…”
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