Search Results - "YUSUKE MAEDA"
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Inflammation in gastric cancer: Interplay of the COX‐2/prostaglandin E2 and Toll‐like receptor/MyD88 pathways
Published in Cancer science (01-04-2016)“…Cyclooxygenase‐2 (COX‐2) and its downstream product prostaglandin E2 (PGE2) play a key role in generation of the inflammatory microenvironment in tumor…”
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2
Negative autoregulation controls size scaling in confined gene expression reactions
Published in Scientific reports (22-06-2022)“…Gene expression via transcription-translation is the most fundamental reaction to sustain biological systems, and complex reactions occur in a small…”
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3
Development of an artificial cell, from self-organization to computation and self-reproduction
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-2011)“…This article describes the state and the development of an artificial cell project. We discuss the experimental constraints to synthesize the most elementary…”
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4
Edge current and pairing order transition in chiral bacterial vortices
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-2021)“…Bacterial suspensions show turbulence-like spatiotemporal dynamics and vortices moving irregularly inside the suspensions. Understanding these ordered vortices…”
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5
Influence of history of falls and physical function on obstacle-straddling behavior
Published in Journal of Physical Therapy Science (01-01-2023)“…[Purpose] This study aimed to clarify the relationship between falls and lower leg motion during obstacle crossing, in which stumbling or tripping is the most…”
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6
Establishment of a reverse genetics system for SARS-CoV-2 using circular polymerase extension reaction
Published in Cell reports (Cambridge) (20-04-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been identified as the causative agent of coronavirus disease 2019 (COVID-19). Although…”
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Phase Separation and Protein Partitioning in Compartmentalized Cell-Free Expression Reactions
Published in Biomacromolecules (09-08-2021)“…Liquid–liquid phase separation (LLPS) is important to control a wide range of reactions from gene expression to protein degradation in a cell-sized space. To…”
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Anomalous Scaling of Gene Expression in Confined Cell-Free Reactions
Published in Scientific reports (09-05-2018)“…Cellular surface breaks the symmetry of molecular diffusion across membrane. Here, we study how steric interactions between the surface and the bulk of…”
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Insights into the Micromechanical Properties of the Metaphase Spindle
Published in Cell (24-06-2011)“…The microtubule-based metaphase spindle is subjected to forces that act in diverse orientations and over a wide range of timescales. Currently, we cannot…”
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10
Protein Needles Designed to Self‐Assemble through Needle Tip Engineering
Published in Small (Weinheim an der Bergstrasse, Germany) (01-03-2022)“…The dynamic process of formation of protein assemblies is essential to form highly ordered structures in biological systems. Advances in structural and…”
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11
Improvement in Epigenetic Aging Clock Induced by BioBran Containing Rice Kefiran in Relation to Various Biomarkers: A Pilot Study
Published in International journal of molecular sciences (01-06-2024)“…Many lifestyle-related diseases such as cancer, dementia, myocardial infarction, and stroke are known to be caused by aging, and the WHO's ICD-11…”
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12
Geometry-driven collective ordering of bacterial vortices
Published in Soft matter (2017)“…Controlling the phases of matter is a challenge that spans from condensed materials to biological systems. Here, by imposing a geometric boundary condition, we…”
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13
Structural remodeling, trafficking and functions of glycosylphosphatidylinositol-anchored proteins
Published in Progress in lipid research (01-10-2011)“…► We review recent progress in studies on glycosylphosphatidylinositol (GPI). ► Three different GPI remodeling reactions occur in GPI-anchored proteins during…”
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Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation
Published in Nature communications (13-02-2020)“…Glycosylphosphatidylinositol (GPI)-anchored proteins and glycosphingolipids interact with each other in the mammalian plasma membranes, forming dynamic…”
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15
Mechanically Distinct Microtubule Arrays Determine the Length and Force Response of the Meiotic Spindle
Published in Developmental cell (22-04-2019)“…The microtubule-based spindle is subjected to various mechanical forces during cell division. How the structure generates and responds to forces while…”
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16
Effects of long DNA folding and small RNA stem–loop in thermophoresis
Published in Proceedings of the National Academy of Sciences - PNAS (30-10-2012)“…In thermophoresis, with the fluid at rest, suspensions move along a gradient of temperature. In an aqueous solution, a PEG polymer suspension is depleted from…”
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17
Thermal separation: interplay between the Soret effect and entropic force gradient
Published in Physical review letters (11-07-2011)“…Thermophoresis, the Soret effect, depletes a high concentration of a polyethylene glycol polymer solution from the hot region and builds a concentration…”
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18
FOXO3 is a latent tumor suppressor for FOXO3-positive and cytoplasmic-type gastric cancer cells
Published in Oncogene (29-04-2021)“…FOXO3 is a member of the FOXO transcription factors thought to play a tumor-suppressor role in gastrointestinal cancer, while tumor-promoting function of FOXO3…”
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Controlling Collective Motion of Kinesin-Driven Microtubules via Patterning of Topographic Landscapes
Published in Nano letters (22-12-2021)“…Biomolecular motor proteins that generate forces by consuming chemical energy obtained from ATP hydrolysis play pivotal roles in organizing cytoskeletal…”
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20
Synthesis and properties of 4′-C-aminoalkyl-2′-fluoro-modified RNA oligomers
Published in Bioorganic & medicinal chemistry (15-08-2018)“…[Display omitted] Synthesis and properties of double-stranded RNAs (dsRNAs) and small interfering RNAs (siRNAs) containing…”
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