Search Results - "YUSOF, Rohana"

Endoplasmic reticulum: a focal point of Zika virus infection by Mohd Ropidi, Muhammad Izzuddin, Khazali, Ahmad Suhail, Nor Rashid, Nurshamimi, Yusof, Rohana

“…Zika virus (ZIKV) belongs to the Flavivirus genus of the Flaviviridae family. It is an arbovirus that can cause congenital abnormalities and is sexually…”
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A combination of doxycycline and ribavirin alleviated chikungunya infection by Rothan, Hussin A, Bahrani, Hirbod, Mohamed, Zulqarnain, Teoh, Teow Chong, Shankar, Esaki M, Rahman, Noorsaadah A, Yusof, Rohana

“…Lack of vaccine and effective antiviral drugs against chikungunya virus (CHIKV) outbreaks have led to significant impact on health care in the developing…”
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Thioguanine-based DENV-2 NS2B/NS3 protease inhibitors: Virtual screening, synthesis, biological evaluation and molecular modelling by Hariono, Maywan, Choi, Sy Bing, Roslim, Ros Fatihah, Nawi, Mohamed Sufian, Tan, Mei Lan, Kamarulzaman, Ezatul Ezleen, Mohamed, Nornisah, Yusof, Rohana, Othman, Shatrah, Abd Rahman, Noorsaadah, Othman, Rozana, Wahab, Habibah A

“…Dengue virus Type 2 (DENV-2) is predominant serotype causing major dengue epidemics. There are a number of studies carried out to find its effective antiviral,…”
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Inhibition of dengue NS2B-NS3 protease and viral replication in Vero cells by recombinant retrocyclin-1 by Rothan, Hussin A, Han, Heh Choon, Ramasamy, Thamil Selvee, Othman, Shatrah, Rahman, Noorsaadah Abd, Yusof, Rohana

“…Global resurgence of dengue virus infections in many of the tropical and subtropical countries is a major concern. Therefore, there is an urgent need for the…”
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Reversible thermo-pneumatic valves on centrifugal microfluidic platforms by Aeinehvand, Mohammad Mahdi, Ibrahim, Fatimah, Harun, Sulaiman Wadi, Kazemzadeh, Amin, Rothan, Hussin A, Yusof, Rohana, Madou, Marc

“…Centrifugal microfluidic systems utilize a conventional spindle motor to automate parallel biochemical assays on a single microfluidic disk. The integration of…”
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Identification of natural antimicrobial agents to treat dengue infection: In vitro analysis of latarcin peptide activity against dengue virus by Rothan, Hussin A, Bahrani, Hirbod, Rahman, Noorsaadah Abd, Yusof, Rohana

“…Although there have been considerable advances in the study of dengue virus, no vaccines or anti-dengue drugs are currently available for humans. Therefore,…”
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Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease by Kiat, Tan Siew, Pippen, Richard, Yusof, Rohana, Ibrahim, Halijah, Khalid, Norzulaani, Rahman, Noorsaadah Abd

“…Boesenbergia rotunda (L.) cyclohexenyl chalcone derivatives, 4-hydroxypanduratin A and panduratin A, showed good competitive inhibitory activities towards…”
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Differential proteome analysis of chikungunya virus infection on host cells by Thio, Christina Li-Ping, Yusof, Rohana, Abdul-Rahman, Puteri Shafinaz Akmar, Karsani, Saiful Anuar

“…Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus that has caused multiple unprecedented and re-emerging outbreaks in both tropical and…”
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Menopause-Associated Depression: Impact of Oxidative Stress and Neuroinflammation on the Central Nervous System-A Review by Liang, Gengfan, Kow, Audrey Siew Foong, Yusof, Rohana, Tham, Chau Ling, Ho, Yu-Cheng, Lee, Ming Tatt

“…Perimenopausal depression, occurring shortly before or after menopause, is characterized by symptoms such as emotional depression, anxiety, and stress, often…”
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Finding Lead Compounds for Dengue Antivirals from a Collection of Old Drugs through In Silico Target Prediction and Subsequent In Vitro Validation by Abdullah, Zafirah Liyana, Chee, Hui-Yee, Yusof, Rohana, Mohd Fauzi, Fazlin

“…Dengue virus (DENV) infection is one of the most widely spread flavivirus infections. Despite the fatality it could cause, no antiviral treatment is currently…”
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Microsphere integrated microfluidic disk: synergy of two techniques for rapid and ultrasensitive dengue detection by Hosseini, Samira, Aeinehvand, Mohammad M., Uddin, Shah M., Benzina, Abderazak, Rothan, Hussin A., Yusof, Rohana, Koole, Leo H., Madou, Marc J., Djordjevic, Ivan, Ibrahim, Fatimah

“…The application of microfluidic devices in diagnostic systems is well-established in contemporary research. Large specific surface area of microspheres, on the…”
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Fusion of protegrin-1 and plectasin to MAP30 shows significant inhibition activity against dengue virus replication by Rothan, Hussin A, Bahrani, Hirbod, Mohamed, Zulqarnain, Abd Rahman, Noorsaadah, Yusof, Rohana

“…Dengue virus (DENV) broadly disseminates in tropical and sub-tropical countries and there are no vaccine or anti-dengue drugs available. DENV outbreaks cause…”
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Boesenbergia rotunda: From Ethnomedicine to Drug Discovery by Karsani, Saiful Anuar, Othman, Shatrah, Othman, Rozana, Yusof, Rohana, Khalid, Norzulaani, Gen-Teck, Foo, Li-Ping, Christina Thio, Sher-Ming, Wong, Heh, Choon Han, Chin-Fei, Chee, Yean-Kee, Lee, Eng-Chong, Tan, Abd Rahman, Noorsaadah

“…Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family. B. rotunda is widely found in Asian countries where it is commonly…”
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Differential Analysis of the Secretome of WRL68 Cells Infected with the Chikungunya Virus by Thio, Christina Li-Ping, Yusof, Rohana, Ashrafzadeh, Ali, Bahari, Syareena, Abdul-Rahman, Puteri Shafinaz, Karsani, Saiful Anuar

“…The Chikungunya virus (CHIKV) is an arthropod borne virus. In the last 50 years, it has been the cause of numerous outbreaks in tropical and temperate regions,…”
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Protegrin-1 Inhibits Dengue NS2B-NS3 Serine Protease and Viral Replication in MK2 Cells by Sasikumer, Pottayil G., Rothan, Hussin A., Yusof, Rohana, Abd Rahman, Noorsaadah, Othman, Shatrah, Abdulrahman, Ammar Y.

“…Dengue diseases have an economic as well as social burden worldwide. In this study, the antiviral activity of protegrin-1 (PG-1, RGGRLCYCRRRFCVCVGR) peptide…”
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Current approaches in antiviral drug discovery against the Flaviviridae family by Baharuddin, Aida, Hassan, Asfarina Amir, Sheng, Gan Chye, Nasir, Shah Bakhtiar, Othman, Shatrah, Yusof, Rohana, Othman, Rozana, Rahman, Noorsaadah Abdul

“…Viruses belonging to the Flaviviridae family primarily spread through arthropod vectors, and are the major causes of illness and death around the globe. The…”
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Scalable Production of Recombinant Membrane Active Peptides and Its Potential as a Complementary Adjunct to Conventional Chemotherapeutics by Rothan, Hussin A, Ambikabothy, Jamunaa, Abdulrahman, Ammar Y, Bahrani, Hirbod, Golpich, Mojtaba, Amini, Elham, A Rahman, Noorsaadah, Teoh, Teow Chong, Mohamed, Zulqarnain, Yusof, Rohana

“…The production of short anticancer peptides in recombinant form is an alternative method for costly chemical manufacturing. However, the limitations of host…”
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A Microfluidic Lab-on-a-Disc (LOD) for Antioxidant Activities of Plant Extracts by Abd Rahman, Nurhaslina, Ibrahim, Fatimah, Aeinehvand, Mohammad M, Yusof, Rohana, Madou, Marc

“…Antioxidants are an important substance that can fight the deterioration of free radicals and can easily oxidize when exposed to light. There are many methods…”
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Purified NS2B/NS3 Serine Protease of Dengue Virus Type 2 Exhibits Cofactor NS2B Dependence for Cleavage of Substrates with Dibasic Amino Acids in Vitro by Yusof, Rohana, Clum, Stephen, Wetzel, Mary, Murthy, H.M.Krishna, Padmanabhan, R.

“…Dengue virus type 2 NS3, a multifunctional protein, has a serine protease domain (NS3pro) that requires the conserved hydrophilic domain of NS2B for protease…”
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Discovery of azetidine based ene-amides as potent bacterial enoyl ACP reductase (FabI) inhibitors by Takhi, Mohamed, Sreenivas, Kandepu, Reddy, Chandrashekar K., Munikumar, Mahadari, Praveena, Kolakota, Sudheer, Pabolu, Rao, Bandaru N.V.M., Ramakanth, Gollamudi, Sivaranjani, Jampala, Mulik, Shardaprasad, Reddy, Yeruva R., Narasimha Rao, Krishnamurthy, Pallavi, Rentala, Lakshminarasimhan, Anirudha, Panigrahi, Sunil K., Antony, Thomas, Abdullah, Iskandar, Lee, Yean K., Ramachandra, Murali, Yusof, Rohana, Rahman, Noorsaadah A., Subramanya, Hosahalli

“…A novel and potent series of ene-amides featuring azetidines has been developed as FabI inhibitors active against drug resistant Gram-positive pathogens…”
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