Search Results - "YUREK, D"

Long distance directional growth of dopaminergic axons along pathways of netrin-1 and GDNF by Zhang, C., Jin, Y., Ziemba, K.S., Fletcher, A.M., Ghosh, B., Truit, E., Yurek, D.M., Smith, G.M.

“…Different experimental and clinical strategies have been used to promote survival of transplanted embryonic ventral mesencephalic (VM) neurons. However, few…”
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Transgene expression in the striatum following intracerebral injections of DNA nanoparticles encoding for human glial cell line-derived neurotrophic factor by Fletcher, A.M, Kowalczyk, T.H, Padegimas, L, Cooper, M.J, Yurek, D.M

“…Abstract A goal of our studies is to develop a potential therapeutic for Parkinson's disease (PD) by a human glial cell line-derived neurotrophic factor…”
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Development and pharmacological characterization of a model of sleep disruption-induced hypersensitivity in the rat by Wodarski, R., Schuh-Hofer, S., Yurek, D.A., Wafford, K.A., Gilmour, G., Treede, R.-D., Kennedy, J.D.

“…Background Sleep disturbance is a commonly reported co‐morbidity in chronic pain patients, and conversely, disruption of sleep can cause acute and long‐lasting…”
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Age and lesion-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles by Yurek, D.M, Hasselrot, U, Cass, W.A, Sesenoglu-Laird, O, Padegimas, L, Cooper, M.J

“…Highlights • Transgene expression in brain is sensitive to aging and pathology. • Transgene expression in astrocytes increases directly with age and severity…”
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Glial Cell Line-Derived Neurotrophic Factor Improves Survival of Dopaminergic Neurons in Transplants of Fetal Ventral Mesencephalic Tissue by Yurek, David M.

“…This study was designed to determine whether or not an exogenous source of glial cell line-derived neurotrophic factor (GDNF) could be delivered continuously…”
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A New Resistance Gene, linB, Conferring Resistance to Lincosamides by Nucleotidylation in Enterococcus faecium HM1025 by BOZDOGAN, B, BERREZOUGA, L, KUO, M.-S, YUREK, D. A, FARLEY, K. A, STOCKMAN, B. J, LECLERCQ, R

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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BDNF Enhances the Functional Reinnervation of the Striatum by Grafted Fetal Dopamine Neurons by Yurek, David M., Lu, William, Hipkens, Susan, Wiegand, Stanley J.

“…Transplantation of fetal dopaminergic neurons to the striatum can ameliorate neurological deficits exhibited by experimental animals and human graft recipients…”
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Differential expression of GDNF, BDNF, and NT-3 in the aging nigrostriatal system following a neurotoxic lesion by Yurek, David M., Fletcher-Turner, Anita

“…Protein levels for brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and glial cell line-derived neurotrophic factor (GDNF) were measured in the…”
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Age-related decline in striatal dopamine release and motoric function in Brown Norway/Fischer 344 hybrid rats by Yurek, David M, Hipkens, Susan B, Hebert, Meleik A, Gash, Don M, Gerhardt, Greg A

“…The Brown Norway/Fischer 344 F1 hybrid rats (F344BNF 1) is a newer rat model and is emerging as an important rodent model of aging. In the present study we…”
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Intranigral Transplants of Fetal Ventral Mesencephalic Tissue Attenuate D1-Agonist-Induced Rotational Behavior by Yurek, David M.

“…Rats were given unilateral 6-hydroxydopamine lesions and tested 4 weeks later for rotational behavior elicited by either systemic or intranigral injections of…”
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Lesion-Induced Increase of BDNF Is Greater in the Striatum of Young versus Old Rat Brain by Yurek, David M., Fletcher-Turner, Anita

“…Young (4–5 month old) and old (32–34 month old) Brown Norway/F344 hybrid rats were given unilateral 6-OHDA lesions of the nigrostriatal pathway. Four weeks…”
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Supranigral injection of neuregulin1-β induces striatal dopamine overflow by Yurek, David M., Zhang, Lixin, Fletcher-Turner, Anita, Seroogy, Kim B.

“…Previous studies have provided anatomical evidence that the functional neuregulin receptor, ErbB4, is present within the ventral midbrain where it is…”
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GDNF partially protects grafted fetal dopaminergic neurons against 6-hydroxydopamine neurotoxicity by Yurek, David M., Fletcher-Turner, Anita

“…Rats were given unilateral 6-hydroxydopamine (6-OHDA) lesions and subsequently received transplants of fetal ventral mesencephalic tissue into the denervated…”
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Dopamine cell replacement: Parkinson's disease by YUREK, D. M, SLADEK, J. R

“…Significant progress in neural transplantation has been observed over the last several decades. As a neuroanatomical tool, neural transplantation studies are…”
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Biosynthesis of the Pipecolate Moiety of Marcfortine A by Kuo, M. S, Yurek, D. A, Mizsak, S. A, Cialdella, J. I, Baczynskyj, L, Marshall, V. P

“…In this paper, we demonstrate that the marcfortine A (MA) producing Penicillium strain incorporates l-lysine, which is metabolized to the pipecolate moiety by…”
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Regional levels of lactate and norepinephrine after experimental brain injury by Prasad, M R, Ramaiah, C, McIntosh, T K, Dempsey, R J, Hipkens, S, Yurek, D

“…The recently developed controlled cortical impact model of brain injury in rats may be an excellent tool by which to attempt to understand the neurochemical…”
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Immunohistochemical detection of the lipid peroxidation product 4-hydroxynonenal after experimental brain injury in the rat by Zhang, Deqing, Dhillon, Harbhajan S, Mattson, Mark P, Yurek, David M, Prasad, Renuka M

“…This study examined the accumulation of the cytotoxic lipid peroxidation product 4-hydroxynonenal (HNE) after lateral fluid percussion (FP) brain injury in…”
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Differentiation in personality descriptions of the self and others by Mirels, H.L., Stevens, F., Greblo, P., Yurek, D.L.

“…Previous studies of the tendency to describe one's own personality or the personality of another in a differentiated, nuanced way have assessed differentiation…”
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Temporal changes in the neurotrophic environment of the denervated striatum as determined by the survival and outgrowth of grafted fetal dopamine neurons by Yurek, David M., Fletcher-Turner, Anita

“…There is growing evidence that the neurotrophic environment of the denervated striatum may change with time following a lesion of the nigrostriatal pathway in…”
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Co-grafts of fetal ventral mesencephalon and fibroblasts expressing sonic hedgehog: effect on survival and function of dopamine grafts by Yurek, D M, Fletcher-Turner, A, Moore, J, Chai, L, Mahanthappa, N

“…Fibroblasts derived from the Rat2 parental cell line were genetically modified to express the cell-associated form of Sonic hedgehog (Shh) and then co-grafted…”
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