Search Results - "YUNSONG YU"
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BacWGSTdb 2.0: a one-stop repository for bacterial whole-genome sequence typing and source tracking
Published in Nucleic acids research (08-01-2021)“…Abstract An increasing prevalence of hospital acquired infections and foodborne illnesses caused by pathogenic and multidrug-resistant bacteria has stimulated…”
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A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae
Published in Journal of global antimicrobial resistance. (01-06-2021)“…•There are multiple definitions of hypervirulent Klebsiella pneumoniae (hvKp).•Mechanisms and epidemiology of carbapenem-resistant K. pneumoniae…”
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ST11, the dominant clone of KPC-producing Klebsiella pneumoniae in China
Published in Journal of antimicrobial chemotherapy (01-02-2011)“…Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae has spread rapidly in China. In this study, we aimed to investigate the molecular…”
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Prevalence of mcr-1 in Escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study
Published in The Lancet infectious diseases (01-04-2017)“…Summary Background Polymyxin antibiotics are used as last-resort therapies to treat infections caused by multidrug-resistant Gram-negative bacteria. The…”
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Emergence of NDM-1-producing Acinetobacter baumannii in China
Published in Journal of antimicrobial chemotherapy (01-06-2011)“…To investigate the prevalence of bla(NDM-1) in Gram-negative bacilli in China. A total of 11 298 clinical Gram-negative bacilli, covering Escherichia coli,…”
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The role of the type VI secretion system vgrG gene in the virulence and antimicrobial resistance of Acinetobacter baumannii ATCC 19606
Published in PloS one (02-02-2018)“…The Type VI Secretion System (T6SS) is an important virulence system that exists in many bacterial pathogens, and has emerged as a potent mediator of…”
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Resistance mechanisms of tigecycline in Acinetobacter baumannii
Published in Frontiers in cellular and infection microbiology (09-05-2023)“…is widely distributed in nature and in hospital settings and is a common pathogen causing various infectious diseases. Currently, the drug resistance rate of…”
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Antibiotic susceptibility patterns and trends of the gram-negative bacteria isolated from the patients in the emergency departments in China: results of SMART 2016-2019
Published in BMC infectious diseases (17-05-2024)“…The study aims were to evaluate the species distribution and antimicrobial resistance profile of Gram-negative pathogens isolated from specimens of…”
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A Biological Inventory of Prophages in A. baumannii Genomes Reveal Distinct Distributions in Classes, Length, and Genomic Positions
Published in Frontiers in microbiology (03-12-2020)“…is of major clinical importance as the bacterial pathogen often causes hospital acquired infections, further complicated by the high prevalence of antibiotic…”
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Defining persistent critical illness based on growth trajectories in patients with sepsis
Published in Critical care (London, England) (18-02-2020)“…Persistent critical illness is common in critically ill patients and is associated with vast medical resource use and poor clinical outcomes. This study aimed…”
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The Rapid Emergence of Tigecycline Resistance in blaKPC–2 Harboring Klebsiella pneumoniae, as Mediated in Vivo by Mutation in tetA During Tigecycline Treatment
Published in Frontiers in microbiology (05-04-2018)“…Tigecycline is one of the last resort treatments for carbapenem-resistant Klebsiella pneumoniae (CRKP) infections. Tigecycline resistance often occurs during…”
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Tigecycline susceptibility and the role of efflux pumps in tigecycline resistance in KPC-producing Klebsiella pneumoniae
Published in PloS one (03-03-2015)“…KPC-producing Klebsiella pneumoniae isolates have emerged as important pathogens of nosocomial infections, and tigecycline is one of the antibiotics…”
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Emergence of a KPC Variant Conferring Resistance to Ceftazidime-Avibactam in a Widespread ST11 Carbapenem-Resistant Klebsiella pneumoniae Clone in China
Published in Frontiers in microbiology (16-08-2021)“…Carbapenem-resistant Klebsiella pneumoniae (CRKP) infection poses a great threat to public health worldwide, and KPC-2-producing strains are the main factors…”
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Diversity of virulence level phenotype of hypervirulent Klebsiella pneumoniae from different sequence type lineage
Published in BMC microbiology (29-08-2018)“…Hypervirulent Klebsiella pneumoniae (hvKP) is emerging around the Asian-Pacific region and it is the major cause of the community-acquired pyogenic liver…”
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Resistance evolution of hypervirulent carbapenem-resistant Klebsiella pneumoniae ST11 during treatment with tigecycline and polymyxin
Published in Emerging microbes & infections (01-01-2021)“…Hypervirulent carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) has recently aroused increasing attention, especially ST11, the predominant CRKP clone in…”
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Colistin-phage combinations decrease antibiotic resistance in Acinetobacter baumannii via changes in envelope architecture
Published in Emerging microbes & infections (01-01-2021)“…Multidrug-resistant bacterial infections are becoming increasingly common, with only few last-resort antibiotics such as colistin available for clinical…”
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Comparison of the ability to identify arterial stiffness between two new anthropometric indices and classical obesity indices in Chinese adults
Published in Atherosclerosis (01-08-2017)“…Abstract Background and aims The association between anthropometric indices of body composition and arterial stiffness is inconclusive. The objective of this…”
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In vitro activity of ceftolozane/tazobactam against Gram-negative bacilli isolated from pediatric patients: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART) 2017–2021, China
Published in Journal of global antimicrobial resistance. (01-09-2024)“…•Gram-negative bacilli were isolated from various paediatric infections.•Ceftolozane/tazobactam (C/T) was active against 76.6% of enterobacterales…”
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BacAnt: A Combination Annotation Server for Bacterial DNA Sequences to Identify Antibiotic Resistance Genes, Integrons, and Transposable Elements
Published in Frontiers in microbiology (23-07-2021)“…Graphical Abstract Overall BacAnt’s service workflow. The figure is adapted with permissions from IntegronFinder ( Cury et al., 2016 ). Whole genome sequencing…”
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Bioinformatic analysis of structures and encoding genes of Escherichia coli surface polysaccharides sheds light on the heterologous biosynthesis of glycans
Published in BMC genomics (04-04-2023)“…Surface polysaccharides (SPs), such as lipopolysaccharide (O antigen) and capsular polysaccharide (K antigen), play a key role in the pathogenicity of…”
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