Search Results - "YUN-YAN XIANG"
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Nitric oxide upregulates microglia phagocytosis and increases transient receptor potential vanilloid type 2 channel expression on the plasma membrane
Published in Glia (01-12-2019)“…Microglia phagocytosis is critical for central nervous system development, and dysregulation of phagocytosis may contribute to a variety of neurological…”
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2
Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling
Published in Cancer research (Chicago, Ill.) (15-07-2005)“…Glypican-3 (GPC3) is a heparan sulfate proteoglycan that is bound to the cell membrane by a glycosyl-phosphatidylinositol anchor. GPC3 is expressed by most…”
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3
Profiles analysis reveals circular RNAs involving zebrafish physiological development
Published in Journal of cellular physiology (01-09-2019)“…Recent studies have found that known functions of circular RNAs (circRNAs) include sequestration of microRNAs (miRNAs) or proteins, modulation of transcription…”
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4
Protective roles of hepatic GABA signaling in acute liver injury of rats
Published in American journal of physiology: Gastrointestinal and liver physiology (01-03-2017)“…γ-Aminobutyric acid (GABA) is produced by various cells through the catalytic activity of glutamic acid decarboxylase (GAD). Activation of type-A GABA receptor…”
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5
GABA coordinates with insulin in regulating secretory function in pancreatic INS-1 β-cells
Published in PloS one (21-10-2011)“…Pancreatic islet β-cells produce large amounts of γ-aminobutyric acid (GABA), which is co-released with insulin. GABA inhibits glucagon secretion by…”
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6
Acupuncture as an adjunctive therapy for gastric ulcer: A modified Delphi consensus study
Published in Complementary therapies in medicine (01-12-2023)“…Acupuncture is often used as an adjunctive therapy for gastric ulcer (GU). However, there is still a lack of evidence on the appropriate and optimal…”
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Nitric oxide signaling inhibits microglia proliferation by activation of protein kinase-G
Published in Nitric oxide (01-01-2020)“…Microglia population is primarily determined by a finely-regulated proliferation process during early development of the central nervous system (CNS). Nitric…”
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8
The gut microbiome and metabolites are altered and interrelated in patients with functional constipation
Published in Frontiers in microbiology (06-12-2023)“…Gut microbiota and metabolites have been identified to contribute to the pathogenesis of functional constipation (FC); however, the underlying mechanism(s)…”
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Advances in acupuncture regulation on the autonomic nervous system from 2013 to 2022: A bibliometric analysis via citespace
Published in Complementary therapies in medicine (01-03-2024)“…To understand research advances and frontiers of acupuncture regulation on the autonomic nervous system (ANS) over the past decade through a bibliometric…”
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10
A GABAergic system in airway epithelium is essential for mucus overproduction in asthma
Published in Nature medicine (01-07-2007)“…γ-Aminobutyric acid (GABA) is an important neurotransmitter that, through the subtype A GABA receptor (GABAAR), induces inhibition in the adult brain. Here we…”
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11
Global trends in research on miRNA-microbiome interaction from 2011 to 2021: A bibliometric analysis
Published in Frontiers in pharmacology (30-08-2022)“…An increasing number of research suggests that the microRNA (miRNA)-microbiome interaction plays an essential role in host health and diseases. This…”
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12
Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease
Published in Proceedings of the National Academy of Sciences - PNAS (22-02-2011)“…Cystic fibrosis is caused by impaired ion transport due to mutated cystic fibrosis transmembrane conductance regulator, accompanied by elevated activity of the…”
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13
Nitric Oxide Critically Regulates Purkinje Neuron Dendritic Development Through a Metabotropic Glutamate Receptor Type 1–Mediated Mechanism
Published in Cerebellum (London, England) (01-08-2020)“…Nitric oxide (NO), specifically derived from neuronal nitric oxide synthase (nNOS), is a well-established regulator of synaptic transmission in Purkinje…”
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14
Autocrine GABA signaling distinctively regulates phenotypic activation of mouse pulmonary macrophages
Published in Cellular immunology (01-10-2018)“…•Both GABAARs and GAD, a GABA synthetic enzyme, are expressed in mouse LMϕs.•GABAARs in LMϕs are down- and up-regulated by “M1” and “M2” stimulants,…”
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15
The Loss of Glypican-3 Induces Alterations in Wnt Signaling
Published in The Journal of biological chemistry (21-01-2005)“…Loss-of-function mutations of the GPC3 gene are the cause of the human Simpson-Golabi-Behmel syndrome. Based on the overgrowth phenotype of the…”
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16
Effects of acupuncture on gut microbiota and short-chain fatty acids in patients with functional constipation: a randomized placebo-controlled trial
Published in Frontiers in pharmacology (01-09-2023)“…Objective: To comprehensively evaluate the effect of acupuncture on gut microbiota, identify specific microbes closely related to the clinical efficacy of…”
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A novel role of intestine epithelial GABAergic signaling in regulating intestinal fluid secretion
Published in American journal of physiology: Gastrointestinal and liver physiology (15-08-2012)“…γ-Aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, and it is produced via the enzymatic activity of glutamic…”
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18
Glypican-3 expression is silenced in human breast cancer
Published in Oncogene (01-11-2001)“…Glypican-3 (GPC3) is a membrane-bound heparan sulfate proteoglycan that is mutated in the Simpson-Golabi-Behmel syndrome. This is an X-linked condition…”
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Versican G3 Domain Regulates Neurite Growth and Synaptic Transmission of Hippocampal Neurons by Activation of Epidermal Growth Factor Receptor
Published in The Journal of biological chemistry (14-07-2006)“…Versican is one of the major extracellular matrix (ECM) proteins in the brain. ECM molecules and their cleavage products critically regulate the growth and…”
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Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes
Published in Diabetologia (01-06-2017)“…Aims/hypothesis This study aimed to elucidate the mechanism of increased proliferation of alpha cells in recent-onset type 1 diabetes. Pancreatic beta cells…”
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