Search Results - "YUEN, E"

Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory by Yuen, E Y, Liu, W, Karatsoreos, I N, Ren, Y, Feng, J, McEwen, B S, Yan, Z

“…Corticosteroid stress hormones have a strong impact on the function of prefrontal cortex (PFC), a central region controlling cognition and emotion, though the…”
Get full text

Estrogen protects against the detrimental effects of repeated stress on glutamatergic transmission and cognition by Wei, J, Yuen, E Y, Liu, W, Li, X, Zhong, P, Karatsoreos, I N, McEwen, B S, Yan, Z

“…Converging evidence suggests that females and males show different responses to stress; however, little is known about the mechanism underlying the sexually…”
Get full text

First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer by Massard, C., Azaro, A., Soria, J.-C., Lassen, U., Le Tourneau, C., Sarker, D., Smith, C., Ohnmacht, U., Oakley, G., Patel, B.K.R., Yuen, E.S.M., Benhadji, K.A., Rodon, J.

“…Deregulated Notch signaling due to mutation or overexpression of ligands and/or receptors is implicated in various human malignancies. γ-Secretase inhibitors…”
Get full text

Safety and clinical activity of the Notch inhibitor, crenigacestat (LY3039478), in an open-label phase I trial expansion cohort of advanced or metastatic adenoid cystic carcinoma by Even, C., Lassen, U., Merchan, J., Le Tourneau, C., Soria, J-C, Ferte, C., Ricci, F., Diener, J. T., Yuen, E., Smith, C., Oakley, G. J., Benhadji, K. A., Massard, Christophe

“…Summary Background Deregulated Notch signaling is implicated in multiple cancers. The phase I trial (I6F-MC-JJCA) investigated the safety and anti-tumor…”
Get full text

Low Vitamin D Status Is an Independent Predictor of Increased Frailty and All-Cause Mortality in Older Men: The Health in Men Study by Wong, Yuen Y. E, McCaul, Kieran A, Yeap, Bu B, Hankey, Graeme J, Flicker, Leon

“…Context and Objective: Hypovitaminosis D and frailty are common in the older population. We aimed to determine whether 25-hydroxyvitamin D [25(OH)D]…”
Get full text

A Comparison of Request Process and Outcomes in Donation After Cardiac Death and Donation After Brain Death: Results From a National Study by Siminoff, L. A., Alolod, G. P., Wilson‐Genderson, M., Yuen, E. Y. N., Traino, H. M.

“…Available literature points to healthcare providers’ discomfort with donation after cardiac death (DCD) and their perception of public reluctance toward the…”
Get full text

A phase 1b study of crenigacestat (LY3039478) in combination with gemcitabine and cisplatin or gemcitabine and carboplatin in patients with advanced or metastatic solid tumors by Massard, C., Cassier, P. A., Azaro, A., Anderson, B., Yuen, E., Yu, D., Oakley, G., Benhadji, K. A., Pant, S.

“…Background Notch signaling plays an integral role in development and tissue homeostasis. Inhibition of Notch signaling has been identified as a reasonable…”
Get full text

Development of a conceptual model of cancer caregiver health literacy by Yuen, E.Y.N., Dodson, S., Batterham, R.W., Knight, T., Chirgwin, J., Livingston, P.M.

“…Caregivers play a vital role in caring for people diagnosed with cancer. However, little is understood about caregivers' capacity to find, understand, appraise…”
Get full text

Serotonin 5-HT1A Receptors Regulate NMDA Receptor Channels through a Microtubule-Dependent Mechanism by Yuen, Eunice Y, Jiang, Qian, Chen, Paul, Gu, Zhenglin, Feng, Jian, Yan, Zhen

“…The serotonin system and NMDA receptors (NMDARs) in prefrontal cortex (PFC) are both critically involved in the regulation of cognition and emotion under…”
Get full text

What is the evidence for sexual reproduction of Phytophthora infestans in Europe? by Yuen, J. E., Andersson, B.

“…The biology of late blight of potato and tomato, caused by Phytophthora infestans, changed when sexual reproduction by the pathogen became possible in many…”
Get full text

In older men, lower plasma 25-hydroxyvitamin D is associated with reduced incidence of prostate, but not colorectal or lung cancer by Wong, Yuen Y E, Hyde, Zoë, McCaul, Kieran A, Yeap, Bu B, Golledge, Jonathan, Hankey, Graeme J, Flicker, Leon

“…Prostate, colorectal and lung cancers are common in men. In this study, we aimed to determine whether vitamin D status is associated with the incidence of…”
Get full text

Nonpharmacological interventions to reduce respiratory viral transmission: an evidence-based review with recommendations by Yuen, E, Fried, J, Salvador, C, Gudis, D A, Schlosser, R J, Nguyen, S A, Brennan, E A, Rowan, N R

“…Viral respiratory infections are a leading cause of worldwide mortality and exert the potential to cause global socioeconomic crises. However, inexpensive,…”
Get full text

2012: A watershed year for Alzheimer’s disease research by Grundman, M, Dibernardo, A, Raghavan, N, Krams, M, Yuen, E

“…Despite negative topline phase 3 clinical trial results for bapineuzumab and solanezumab in mild to moderate AD, findings from these trials and recent advances…”
Get full text

Intermittency in pseudorapidity space of pp collisions at √s $ \sqrt s $ = 7 TeV by Ong, Z., Yuen, E., Ang, H.W., Chan, A.H., Oh, C.H.

“…The intermittency-type fluctuations in the pseudorapidity space of pp collisions at $ \sqrt s $ = 7 TeV done at the LHC is investigated, by analysing the…”
Get full text

Reliability of shear wave ultrasound elastography for neck lesions identified in routine clinical practice by Bhatia, K, Tong, C S L, Cho, C C M, Yuen, E H Y, Lee, J, Ahuja, A T

“…To evaluate the reliability of shear wave ultrasound elastography (SWE) in the neck. 176 neck lesions (40 thyroid, 56 lymph nodes, 46 salivary, 34…”
Get more information

Displacement of US‐1 clonal lineage by a new lineage of Phytophthora infestans on potato in Kenya and Uganda by Njoroge, A. W., Tusiime, G., Forbes, G. A., Yuen, J. E.

“…Phytophthora infestans, the pathogen responsible for causing late blight in potato and tomato, is a rapidly evolving and highly adaptable pathogen. Following…”
Get full text

Chou-Yang Model for Forward-Backward Multiplicity Correlations at 7 TeV using Generalized Multiplicity Distribution by Phang, S.W., Chan, A.H., Oh, C.H., Yuen, E., Ong, Z., Leong, Q.X.

“…The basis of the Chou-Yang model is made up of a stochastic and non-stochastic distribution and has been successful in describing forward-backward…”
Get full text

Phenotypic Variation Within a Clonal Lineage of Phytophthora infestans Infecting both Tomato and Potato in Nicaragua by BLANDON-DIAZ, J. U, WIDMARK, A.-K, HANNUKKALA, A, ANDERSSON, B, HÖGBERG, N, YUEN, J. E

“…Late blight caused by Phytophthora infestans (Mont.) de Bary is a constraint to both potato and tomato crops in Nicaragua. The hypothesis that the Nicaraguan…”
Get full text

Randomized, controlled, dose-ranging trial of carisbamate for partial-onset seizures by FAUGHT, E, HOLMES, G. L, ROSENFELD, W. E, NOVAK, G, NETO, W, GREENSPAN, A, SCHMITT, J, YUEN, E, REINES, S, HAAS, M

“…To evaluate the efficacy, safety, and tolerability of carisbamate (CRS), an investigational drug, as adjunctive treatment for partial-onset seizures in adults…”
Get full text

Homocysteine, frailty, and all-cause mortality in older men: the health in men study by Wong, Yuen Y E, Almeida, Osvaldo P, McCaul, Kieran A, Yeap, Bu B, Hankey, Graeme J, Flicker, Leon

“…Frailty and hyperhomocysteinemia are common in the older population. The researchers' objectives were to determine whether elevated homocysteine (tHcy) is…”
Get full text