Search Results - "YUELIN ZHU"

Transcriptome analysis revealed expression of genes related to anthocyanin biosynthesis in eggplant (Solanum melongena L.) under high-temperature stress by Zhang, Shengmei, Zhang, Aidong, Wu, Xuexia, Zhu, Zongwen, Yang, Zuofen, Zhu, Yuelin, Zha, Dingshi

“…Anthocyanin synthesis is affected by many factors, among which temperature is an important environmental factor. Eggplant is usually exposed to high…”
Get full text

Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma by Chaisaingmongkol, Jittiporn, Budhu, Anuradha, Dang, Hien, Rabibhadana, Siritida, Pupacdi, Benjarath, Kwon, So Mee, Forgues, Marshonna, Pomyen, Yotsawat, Bhudhisawasdi, Vajarabhongsa, Lertprasertsuke, Nirush, Chotirosniramit, Anon, Pairojkul, Chawalit, Auewarakul, Chirayu U., Sricharunrat, Thaniya, Phornphutkul, Kannika, Sangrajrang, Suleeporn, Cam, Maggie, He, Ping, Hewitt, Stephen M., Ylaya, Kris, Wu, Xiaolin, Andersen, Jesper B., Thorgeirsson, Snorri S., Waterfall, Joshua J., Zhu, Yuelin J., Walling, Jennifer, Stevenson, Holly S., Edelman, Daniel, Meltzer, Paul S., Loffredo, Christopher A., Hama, Natsuko, Shibata, Tatsuhiro, Wiltrout, Robert H., Harris, Curtis C., Mahidol, Chulabhorn, Ruchirawat, Mathuros, Wang, Xin W.

“…Intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC) are clinically disparate primary liver cancers with etiological and biological…”
Get full text

A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors by Petrini, Iacopo, Meltzer, Paul S, Kim, In-Kyu, Lucchi, Marco, Park, Kang-Seo, Fontanini, Gabriella, Gao, James, Zucali, Paolo A, Calabrese, Fiorella, Favaretto, Adolfo, Rea, Federico, Rodriguez-Canales, Jaime, Walker, Robert L, Pineda, Marbin, Zhu, Yuelin J, Lau, Christopher, Killian, Keith J, Bilke, Sven, Voeller, Donna, Dakshanamurthy, Sivanesan, Wang, Yisong, Giaccone, Giuseppe

“…Giuseppe Giaccone and colleagues identify a recurrent missense mutation in GTF2I in a high percentage of thymic epithelial tumors. The mutation occurs more…”
Get full text

Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans by Mitchell, Khadijah A., Nichols, Noah, Tang, Wei, Walling, Jennifer, Stevenson, Holly, Pineda, Marbin, Stefanescu, Roxana, Edelman, Daniel C., Girvin, Andrew T., Zingone, Adriana, Sinha, Sanju, Bowman, Elise, Rossi, Emily L., Arauz, Rony F., Jack Zhu, Yuelin, Lack, Justin, Weingartner, Elizabeth, Waterfall, Joshua J., Pine, Sharon R., Simmons, John, Meltzer, Paul, Ryan, Bríd M.

“…Reducing or eliminating persistent disparities in lung cancer incidence and survival has been challenging because our current understanding of lung cancer…”
Get full text

The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology by ABAAN, Ogan D, POLLEY, Eric C, HOLBECK, Susan L, SIMON, Richard M, DOROSHOW, James H, POMMIER, Yves, MELTZER, Paul S, DAVIS, Sean R, ZHU, Yuelin J, BILKE, Sven, WALKER, Robert L, PINEDA, Marbin, GINDIN, Yevgeniy, YUAN JIANG, REINHOLD, William C

“…The NCI-60 cell lines are the most frequently studied human tumor cell lines in cancer research. This panel has generated the most extensive cancer…”
Get full text

SRAdb: query and use public next-generation sequencing data from within R by Zhu, Yuelin, Stephens, Robert M, Meltzer, Paul S, Davis, Sean R

“…The Sequence Read Archive (SRA) is the largest public repository of sequencing data from the next generation of sequencing platforms including Illumina (Genome…”
Get full text

Bromodomain and Extraterminal Protein Inhibitor JQ1 Suppresses Thyroid Tumor Growth in a Mouse Model by Zhu, Xuguang, Enomoto, Keisuke, Zhao, Li, Zhu, Yuelin J, Willingham, Mark C, Meltzer, Paul, Qi, Jun, Cheng, Sheue-Yann

“…New therapeutic approaches are needed for patients with thyroid cancer refractory to radioiodine treatment. An inhibitor of bromodomain and extraterminal…”
Get full text

Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling by Grøntved, Lars, Waterfall, Joshua J., Kim, Dong Wook, Baek, Songjoon, Sung, Myong-Hee, Zhao, Li, Park, Jeong Won, Nielsen, Ronni, Walker, Robert L., Zhu, Yuelin J., Meltzer, Paul S., Hager, Gordon L., Cheng, Sheue-yann

“…A bimodal switch model is widely used to describe transcriptional regulation by the thyroid hormone receptor (TR). In this model, the unliganded TR forms…”
Get full text

Genome-Wide Identification and Functional Characterization of the Cation Proton Antiporter (CPA) Family Related to Salt Stress Response in Radish ( Raphanus sativus L.) by Wang, Yan, Ying, Jiali, Zhang, Yang, Xu, Liang, Zhang, Wanting, Ni, Meng, Zhu, Yuelin, Liu, Liwang

“…The CPA (cation proton antiporter) family plays an essential role during plant stress tolerance by regulating ionic and pH homeostasis of the cell. Radish…”
Get full text

Drug-Eluting Stent Targeting Sp-1-Attenuated Restenosis by Engaging YAP-Mediated Vascular Smooth Muscle Cell Phenotypic Modulation by Huang, Chen, Zhao, Jie, Zhu, Yuelin

“…Background Activation of the YAP (Yes-associated protein) pathway has been demonstrated to be related to smooth muscle cells (SMCs) phenotypic modulation and…”
Get full text

CDX1–microRNA-215 axis regulates colorectal cancer stem cell differentiation by Jones, Matthew F., Hara, Toshifumi, Francis, Princy, Li, Xiao Ling, Bilke, Sven, Zhu, Yuelin, Pineda, Marbin, Subramanian, Murugan, Bodmer, Walter F., Lal, Ashish

“…The transcription factor caudal-type homeobox 1 (CDX1) is a key regulator of differentiation in the normal colon and in colorectal cancer (CRC). CDX1 activates…”
Get full text

NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia by Matsukawa, Toshihiro, Yin, Mianmian, Nigam, Nupur, Negi, Vijay, Li, Li, Small, Donald, Zhu, Yuelin J., Walker, Robert L., Meltzer, Paul S., Aplan, Peter D.

Get full text

Targeting MYC as a Therapeutic Intervention for Anaplastic Thyroid Cancer by Enomoto, Keisuke, Zhu, Xuguang, Park, Sunmi, Zhao, Li, Zhu, Yuelin J., Willingham, Mark C., Qi, Jun, Copland, John A., Meltzer, Paul, Cheng, Sheue-yann

“…Abstract Context: Recent studies showed that transcription of the MYC gene is driven by the interaction of bromodomain and extraterminal domain (BET) proteins…”
Get full text

Recurrent epimutation of SDHC in gastrointestinal stromal tumors by Killian, J Keith, Miettinen, Markku, Walker, Robert L, Wang, Yonghong, Zhu, Yuelin Jack, Waterfall, Joshua J, Noyes, Natalia, Retnakumar, Parvathy, Yang, Zhiming, Smith, Jr, William I, Killian, M Scott, Lau, C Christopher, Pineda, Marbin, Walling, Jennifer, Stevenson, Holly, Smith, Carly, Wang, Zengfeng, Lasota, Jerzy, Kim, Su Young, Boikos, Sosipatros A, Helman, Lee J, Meltzer, Paul S

“…Succinate dehydrogenase (SDH) is a conserved effector of cellular metabolism and energy production, and loss of SDH function is a driver mechanism in several…”
Get more information

Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer by Bilke, Sven, Schwentner, Raphaela, Yang, Fan, Kauer, Maximilian, Jug, Gunhild, Walker, Robert L, Davis, Sean, Zhu, Yuelin J, Pineda, Marbin, Meltzer, Paul S, Kovar, Heinrich

“…Deregulated E2F transcription factor activity occurs in the vast majority of human tumors and has been solidly implicated in disturbances of cell cycle…”
Get full text

Mutations of epigenetic regulatory genes are common in thymic carcinomas by Wang, Yisong, Thomas, Anish, Lau, Christopher, Rajan, Arun, Zhu, Yuelin, Killian, J. Keith, Petrini, Iacopo, Pham, Trung, Morrow, Betsy, Zhong, Xiaogang, Meltzer, Paul S., Giaccone, Giuseppe

“…Genetic alterations and etiology of thymic epithelial tumors (TETs) are largely unknown, hampering the development of effective targeted therapies for patients…”
Get full text

Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer by Li, Xiao Ling, Subramanian, Murugan, Jones, Matthew F., Chaudhary, Ritu, Singh, Deepak K., Zong, Xinying, Gryder, Berkley, Sindri, Sivasish, Mo, Min, Schetter, Aaron, Wen, Xinyu, Parvathaneni, Swetha, Kazandjian, Dickran, Jenkins, Lisa M., Tang, Wei, Elloumi, Fathi, Martindale, Jennifer L., Huarte, Maite, Zhu, Yuelin, Robles, Ana I., Frier, Susan M., Rigo, Frank, Cam, Maggie, Ambs, Stefan, Sharma, Sudha, Harris, Curtis C., Dasso, Mary, Prasanth, Kannanganattu V., Lal, Ashish

“…Basal p53 levels are tightly suppressed under normal conditions. Disrupting this regulation results in elevated p53 levels to induce cell cycle arrest,…”
Get full text

Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background by Yin, Mianmian, Chung, Yang Jo, Lindsley, R. Coleman, Walker, Robert L., Zhu, Yuelin J., Ebert, Benjamin L., Meltzer, Paul S., Aplan, Peter D.

“…Approximately 10% of NUP98-PHF23 (NP23) mice develop an aggressive acute lymphoblastic leukemia of B-1 lymphocyte progenitor origin (pro-B1 ALL), accompanied…”
Get full text

Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis by Hirsch, Daniela, Wangsa, Darawalee, Zhu, Yuelin J, Hu, Yue, Edelman, Daniel C, Meltzer, Paul S, Heselmeyer-Haddad, Kerstin, Ott, Claudia, Kienle, Peter, Galata, Christian, Horisberger, Karoline, Ried, Thomas, Gaiser, Timo

“…Patients with inflammatory bowel diseases, that is, ulcerative colitis and Crohn's disease (CD), face an increased risk of developing colorectal cancer (CRC)…”
Get full text

The DNA Methyltransferase Inhibitor 5-Aza-4'-thio-2'-Deoxycytidine Induces C>G Transversions and Acute Lymphoid Leukemia Development by Bertoli, Ryan M, Chung, Yang Jo, Difilippantonio, Michael J, Wokasch, Anthony, Marasco, Madison R B, Klimaszewski, Haley, Gammell, Susannah, Zhu, Yuelin J, Walker, Robert L, Cao, Dengchao, Khanna, Ajay, Walter, Matthew J, Doroshow, James H, Meltzer, Paul S, Aplan, Peter D

“…DNA methyltransferase inhibitors (DNMTi), most commonly cytidine analogs, are compounds that decrease 5'-cytosine methylation. DNMTi are used clinically based…”
Get full text