Search Results - "YUDKIN, J. S"
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Comparison of various surrogate obesity indicators as predictors of cardiovascular mortality in four European populations
Published in European journal of clinical nutrition (01-12-2013)“…Background/Objectives: Body mass index (BMI) is the most commonly used surrogate marker for evaluating the risk of cardiovascular disease (CVD) mortality in…”
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Exercise effects on perivascular adipose tissue: endocrine and paracrine determinants of vascular function
Published in British journal of pharmacology (01-10-2017)“…Obesity is a global epidemic, accompanied by increased risk of type 2 diabetes and cardiovascular disease. Adipose tissue hypertrophy is associated with…”
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Intensified glucose lowering in type 2 diabetes: time for a reappraisal
Published in Diabetologia (01-10-2010)Get full text
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Insulin resistance and the metabolic syndrome--or the pitfalls of epidemiology
Published in Diabetologia (01-08-2007)“…The clustering of dyslipidaemia, hypertension and glucose intolerance, predominantly in overweight individuals, has been ascribed many names, including…”
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Adipose tissue, insulin action and vascular disease: inflammatory signals
Published in International Journal of Obesity (01-12-2003)“…Insulin resistance, both in nondiabetic and diabetic subjects, is frequently associated with obesity, particularly an excess of central fat. Many of the…”
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insulin dilemma in resource-limited countries. A way forward
Published in Diabetologia (2011)“…The International Insulin Foundation (IIF) has developed and validated a needs-assessment instrument called the Rapid Assessment Protocol for Insulin Access…”
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Adiposity and Hyperinsulinemia in Indians Are Present at Birth
Published in The journal of clinical endocrinology and metabolism (01-12-2002)“…We studied body size and cord blood leptin and insulin concentrations in newborn urban Indian (Pune, India) and white Caucasian (London, UK) babies to test the…”
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The Diabetes UK Mozambique Twinning Programme. Results of improvements in diabetes care in Mozambique: a reassessment 6 years later using the Rapid Assessment Protocol for Insulin Access
Published in Diabetic medicine (01-08-2010)“…Diabet. Med. 27, 855–861 (2010) Objective To assess improvements in diabetes care in Mozambique between 2003 and 2009 following the implementation of the…”
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Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo
Published in The journal of clinical endocrinology and metabolism (01-12-1997)“…We measured arterio-venous differences in concentrations of tumor necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6) across a sc adipose tissue bed in…”
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Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?
Published in Atherosclerosis (01-02-2000)“…There is mounting evidence that inflammation plays a role in the development of coronary heart disease (CHD). Observations have been made linking the presence…”
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Book Review Journal Article -
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Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study
Published in BMJ (12-08-2000)“…Abstract Objective: To determine the relation between systolic blood pressure over time and the risk of macrovascular or microvascular complications in…”
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Low-grade inflammation may play a role in the etiology of the metabolic syndrome in patients with coronary heart disease: the HIFMECH study
Published in Metabolism, clinical and experimental (01-07-2004)“…Risk of coronary heart disease has been related to insulin resistance, but the mechanism for this is incompletely understood. Variables attributed to insulin…”
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The epidemic of pre-diabetes: the medicine and the politics
Published in BMJ (Online) (15-07-2014)“…Pre-diabetes is an umbrella tent and the most widely used phrase to describe a blood concentration of glucose or glycated hemoglobin (HbA1c) that lies above…”
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Association of Plasminogen Activator Inhibitor (PAI)-1 (SERPINE1) SNPs With Myocardial Infarction, Plasma PAI-1, and Metabolic Parameters: The HIFMECH Study
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-2007)“…OBJECTIVE—The purpose of this study was to investigate the effects of plasminogen activator inhibitor-1 (PAI-1) gene (SERPINE1) single nucleotide polymorphisms…”
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Using individual patient data in meta-analyses of glucose-lowering studies
Published in Diabetologia (2010)Get full text
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central roles of obesity-associated dyslipidaemia, endothelial activation and cytokines in the Metabolic Syndrome--an analysis by structural equation modelling
Published in International Journal of Obesity (01-07-2002)“…Hypothesis: The multi-faceted components of the metabolic syndrome now include markers of inflammation and endothelial activation. Despite this growing body of…”
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Inflammation, obesity, and the metabolic syndrome
Published in Hormone and metabolic research (01-10-2007)“…Adipose tissue expresses cytokines which inhibit insulin signalling pathways. Obesity also results in impairment of endothelium-dependent vasodilatation to…”
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Abnormalities of coagulation and fibrinolysis in insulin resistance : Evidence for a common antecedent?
Published in Diabetes care (01-04-1999)“…Insulin resistance is associated not only with the classic cardiovascular risk factors of hypertension and dyslipidemia, but also with several disorders of…”
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Conference Proceeding Journal Article -
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What is innovation in the area of medicines? The example of insulin and diabetes
Published in Diabetic medicine (01-12-2019)Get full text
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Implications of the United Kingdom prospective diabetes study
Published in Primary care (01-12-1999)“…The United Kingdom Prospective Diabetes Study (UKPDS) is the largest ever study to clarify the role of glycemia and blood pressure control in improving…”
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