Search Results - "YU, FUJUN"

An Inflammatory Response-Related Gene Signature Can Impact the Immune Status and Predict the Prognosis of Hepatocellular Carcinoma by Lin, Zhuo, Xu, Qian, Miao, Dan, Yu, Fujun

“…Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, which makes the prognostic prediction challenging. As part of the active cross-talk between…”
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NEAT1 accelerates the progression of liver fibrosis via regulation of microRNA-122 and Kruppel-like factor 6 by Yu, Fujun, Jiang, Zhe, Chen, Bicheng, Dong, Peihong, Zheng, Jianjian

“…Long non-coding RNAs (lncRNAs) have been reported to be involved in many important biological processes including proliferation, apoptosis, differentiation,…”
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Targeting Hepatic Stellate Cell Death to Reverse Hepatic Fibrosis by Zhang, Xiangting, Zeng, Yuan, Zhao, Luying, Xu, Qian, Miao, Dan, Yu, Fujun

“…To date, the incidence and mortality of chronic liver diseases such as cirrhosis and hepatocellular carcinoma due to the continued progression of hepatic…”
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Association between triglyceride-glucose index and all-cause mortality in critically ill patients with ischemic stroke: analysis of the MIMIC-IV database by Cai, Weimin, Xu, Jun, Wu, Xiao, Chen, Zhuoyan, Zeng, Liuwei, Song, Xian, Zeng, Yuan, Yu, Fujun

“…The triglyceride-glucose (TyG) index was significantly associated with insulin resistance (IR). Several studies have validated the effect of TyG index on…”
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LincRNA-p21 Inhibits the Wnt/β-Catenin Pathway in Activated Hepatic Stellate Cells via Sponging MicroRNA-17-5p by Yu, Fujun, Guo, Yong, Chen, Bicheng, Shi, Liang, Dong, Peihong, Zhou, Mengtao, Zheng, Jianjian

“…Background/Aims: It is known that the activation of hepatic stellate cells (HSCs) is a pivotal step in the initiation and progression of liver fibrosis…”
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Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy by Mao, Yuqing, Zhang, Shaoren, Yu, Fujun, Li, Huanqing, Guo, Chuanyong, Fan, Xiaoming

“…Ghrelin is a stomach-derived growth hormone secretagogue that promotes various physiological effects, including energy metabolism and amelioration of…”
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Hepatic stellate cell is activated by microRNA-181b via PTEN/Akt pathway by Zheng, Jianjian, Wu, Cunzao, Xu, Ziqiang, Xia, Peng, Dong, Peihong, Chen, Bicheng, Yu, Fujun

“…Activation of hepatic stellate cells (HSCs) is an essential event in the initiation and progression of liver fibrosis. MicroRNAs have been shown to play a…”
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Salidroside ameliorates acetaminophen-induced acute liver injury through the inhibition of endoplasmic reticulum stress-mediated ferroptosis by activating the AMPK/SIRT1 pathway by Xu, Jun, Zhao, Luying, Zhang, Xiangting, Ying, Kanglei, Zhou, Ruoru, Cai, Weimin, Wu, Xiao, Jiang, Haoran, Xu, Qian, Miao, Dan, Zeng, Yuan, Yu, Fujun

“…Acetaminophen (APAP) overdose has long been considered a major cause of drug-induced liver injury. Ferroptosis is a type of programmed cell death mediated by…”
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lincRNA‐p21 inhibits hepatic stellate cell activation and liver fibrogenesis via p21 by Zheng, Jianjian, Dong, Peihong, Mao, Yuqing, Chen, Shaolong, Wu, Xiaoli, Li, Guojun, Lu, Zhongqiu, Yu, Fujun

“…Long non‐coding RNAs are involved in various biological processes and diseases. The biological role of long intergenic non‐coding RNA‐p21 (lincRNA‐p21) in…”
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Curcumin up‐regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA‐mediated control of DNA methylation – a novel mechanism suppressing liver fibrosis by Zheng, Jianjian, Wu, Cunzao, Lin, Zhuo, Guo, Yong, Shi, Liang, Dong, Peihong, Lu, Zhongqiu, Gao, Shenmeng, Liao, Yi, Chen, Bicheng, Yu, Fujun

“…Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) has been reported to play a role in the suppression of activated hepatic stellate cells…”
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Ghrelin Attenuated Lipotoxicity via Autophagy Induction and Nuclear Factor-κB Inhibition by Mao, Yuqing, Cheng, Jian, Yu, Fujun, Li, Huanqing, Guo, Chuanyong, Fan, Xiaoming

“…Background/Aims: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. Autophagy is associated with NAFLD. Ghrelin is a…”
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Loss of lncRNA-SNHG7 Promotes the Suppression of Hepatic Stellate Cell Activation via miR-378a-3p and DVL2 by Yu, Fujun, Dong, Peihong, Mao, Yefan, Zhao, Binyu, Huang, Zhiming, Zheng, Jianjian

“…Small nuclear RNA host gene 7 (SNHG7), a novel long non-coding RNA (lncRNA), acts as an oncogene in cancers. However, whether SNHG7 is involved in hepatic…”
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Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver Fibrosis by Dong, Peihong, Chen, Bi-Cheng, Lu, Zhongqiu, Yu, Fujun, Zheng, Jianjian

“…Previously, we found that long intergenic noncoding RNA-p21 (lincRNA-p21) inhibits hepatic stellate cell (HSC) activation and liver fibrosis via p21. However,…”
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Activation of Hepatic Stellate Cells is Inhibited by microRNA-378a-3p via Wnt10a by Yu, Fujun, Fan, XuFei, Chen, Bicheng, Dong, Peihong, Zheng, Jianjian

“…Background/Aims: Wnt/β-catenin pathway is involved in liver fibrosis and microRNAs (miRNAs) are considered as key regulators of the activation of hepatic…”
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Combined OLA1 and CLEC3B Gene Is a Prognostic Signature for Hepatocellular Carcinoma and Impact Tumor Progression by Chen, Zhoufeng, Zeng, Liuwei, Chen, Zhuoyan, Xu, Jun, Zhang, Xiangting, Ying, Huiya, Zeng, Yuan, Yu, Fujun

“…Hepatocellular carcinoma (HCC), partly because of its complexity and high heterogeneity, has a poor prognosis and an extremely high mortality rate. In this…”
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microRNA-150: a promising novel biomarker for hepatitis B virus-related hepatocellular carcinoma by Yu, Fujun, Lu, Zhongqiu, Chen, Bicheng, Dong, Peihong, Zheng, Jianjian

“…Chronic hepatitis B virus (HBV) infection is a known major etiological factor for hepatocellular carcinoma (HCC) development. Alpha-fetoprotein (AFP) is widely…”
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Correction: LncRNA-MEG3 inhibits activation of hepatic stellate cells through SMO protein and miR-212 by Yu, Fujun, Geng, Wujun, Dong, Peihong, Huang, Zhiming, Zheng, Jianjian

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MicroRNA-125a-5p Contributes to Hepatic Stellate Cell Activation through Targeting FIH1 by Li, Guojun, Li, Jing, Li, Changshui, Qi, Honggang, Dong, Peihong, Zheng, Jianjian, Yu, Fujun

“…Background/Aims: Emerging evidence shows that microRNAs (miRNAs) play a crucial role in the regulation of activation, proliferation and apoptosis of hepatic…”
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Epigenetically-Regulated MicroRNA-9-5p Suppresses the Activation of Hepatic Stellate Cells via TGFBR1 and TGFBR2 by Yu, Fujun, Chen, BiCheng, Fan, XuFei, Li, Guojun, Dong, Peihong, Zheng, Jianjian

“…Background/Aims: Recently, microRNAs (miRNAs) have been demonstrated to act as regulators of activation of hepatic stellate cells (HSCs). It is well known that…”
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MicroRNA-30a Suppresses the Activation of Hepatic Stellate Cells by Inhibiting Epithelial-to-Mesenchymal Transition by Zheng, Jianjian, Wang, Wei, Yu, Fujun, Dong, Peihong, Chen, Bicheng, Zhou, Meng-Tao

“…Background/Aims: The activation of hepatic stellate cells (HSCs) is considered as a pivotal event in liver fibrosis and epithelial-mesenchymal transition (EMT)…”
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