Search Results - "YOUNGMAN OH"

IGFBP-3/IGFBP-3 Receptor System as an Anti-Tumor and Anti-Metastatic Signaling in Cancer by Cai, Qing, Dozmorov, Mikhail, Oh, Youngman

“…Insulin-like growth factor binding protein-3 (IGFBP-3) is a p53 tumor suppressor-regulated protein and a major carrier for IGFs in circulation. Among six…”
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The insulin-like growth factor system in chronic kidney disease: Pathophysiology and therapeutic opportunities by Oh, Youngman

“…abstract The growth hormone–insulin-like growth factor–insulin-like growth factor binding protein (GH–IGF–IGFBP) axis plays a critical role in the maintenance…”
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Alpha-1 Antitrypsin Inhibits Tumorigenesis and Progression of Colitis-Associated Colon Cancer through Suppression of Inflammatory Neutrophil-Activated Serine Proteases and IGFBP-3 Proteolysis by Cai, Qing, Kim, Minsun, Harada, Aki, Idowu, Michael O, Sundaresan, Gobalakrishnan, Zweit, Jamal, Oh, Youngman

“…Colitis-associated colon cancer (CAC) accompanies the massive infiltration of neutrophils during tumorigenesis and progression of CAC. Depletion of neutrophils…”
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Insulin-like growth factor binding protein-3 induces senescence by inhibiting telomerase activity in MCF-7 breast cancer cells by Kwon, Ahreum, Chae, Hyun Wook, Lee, Woo Jung, Kim, JungHyun, Kim, Ye Jin, Ahn, Jungmin, Oh, Youngman, Kim, Ho-Seong

“…Insulin-like growth factor binding protein-3 (IGFBP-3) has been known to inhibit cell proliferation and exert tumor-suppressing effects depending on the cell…”
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Identification of a Novel Cell Death Receptor Mediating IGFBP-3-induced Anti-tumor Effects in Breast and Prostate Cancer by Ingermann, Angela R., Yang, Yong-Feng, Han, Jinfeng, Mikami, Aki, Garza, Amanda E., Mohanraj, Lathika, Fan, Lingbo, Idowu, Michael, Ware, Joy L., Kim, Ho-Seong, Lee, Dae-Yeol, Oh, Youngman

“…Insulin-like growth factor-binding protein-3 (IGFBP-3), a major regulator of endocrine actions of IGFs, is a p53-regulated potent apoptotic factor and is…”
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Suppression of IGF binding protein‐3 by palmitate promotes hepatic inflammatory responses by Min, Hae‐Ki, Maruyama, Hitoshi, Jang, Byoung Kuk, Shimada, Masahiko, Mirshahi, Faridoddin, Ren, Shunlin, Oh, Youngman, Puri, Puneet, Sanyal, Arun J.

“…ABSTRACT IGF‐binding protein‐3 (IGFBP‐3) is a liver‐derived, anti‐inflammatory molecule that is decreased in obesity, a key risk factor for nonalcoholic fatty…”
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Therapeutic potential of alpha-1 antitrypsin in human disease by Kim, Minsun, Cai, Qing, Oh, Youngman

“…Alpha-1 antitrypsin (AAT), an alpha globulin glycoprotein, is a member of the serine protease inhibitor (serpin) superfamily. The clinical significance of AAT…”
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IGFBP-3 inhibits cytokine-induced insulin resistance and early manifestations of atherosclerosis by Mohanraj, Lathika, Kim, Ho-Seong, Li, Wei, Cai, Qing, Kim, Ki Eun, Shin, Hye-Jung, Lee, Yong-Jae, Lee, Woo Jung, Kim, Jung Hyun, Oh, Youngman

“…Metabolic syndrome is associated with visceral obesity, insulin resistance and an increased risk of cardiovascular diseases. Visceral fat tissue primarily…”
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Relationship of Serum Total Insulin-Like Growth Factor Binding Protein-3 with Insulin-Like Growth Factor-I and Glucose Tolerance in Korean Children and Adolescents by Kim, Sun-Young, Kim, Minsun, Oh, Youngman, Lee, Dae-Yeol

“…Insulin is important in glucose metabolism. However, insulin-like growth factor binding protein (IGFBP) also plays an important role in glucose homeostasis,…”
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Targeting IGF-I, IGFBPs and IGF-I receptor system in cancer: the current and future in breast cancer therapy by Mohanraj, Lathika, Oh, Youngman

“…The IGF system plays a major role in growth, development and maintenance of homeostasis in normal cells and also contributes towards proliferation of malignant…”
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Electronic phase coherence and relaxation in graphene field effect transistor by Oh, Youngman, Eom, Jonghwa, Koo, Hyun Cheol, Han, Suk Hee

“…Using the low-field magnetoresistance measurement we have studied the electronic phase coherence of the graphene field effect transistor for different carrier…”
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Effect of Intense Exercise on Inflammatory Cytokines and Growth Mediators in Adolescent Boys by Nemet, Dan, Oh, Youngman, Kim, Ho-Seong, Hill, MaryAnn, Cooper, Dan M

“…Exercise can enhance growth and development in children, but recent investigations have revealed an intriguing paradox. Namely, the early (4-5 weeks) response…”
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Insulin‐like growth factor binding protein 3 as an anticancer molecule in Ewing's sarcoma by Benini, Stefania, Zuntini, Monia, Manara, Maria Cristina, Cohen, Pinchas, Nicoletti, Giordano, Nanni, Patrizia, Oh, Youngman, Picci, Piero, Scotlandi, Katia

“…The IGF/IGF‐IR system plays a major role in the pathogenesis and progression of Ewing's sarcoma. In this article, the authors evaluated whether the…”
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Insulin-like growth factor-binding protein 3 induces caspase-dependent apoptosis through a death receptor-mediated pathway in MCF-7 human breast cancer cells by KIM, Ho-Seong, INGERMANN, Angela R, TSUBAKI, Junko, TWIGG, Stephen M, WALKER, Gillian E, YOUNGMAN OH

“…Insulin-like growth factor-binding protein (IGFBP)-3 has been shown to potently inhibit cell proliferation in various cell systems. However, the specific…”
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Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor β2-induced growth inhibition in human breast cancer cells by GUCEV, Z. S, YOUNGMAN OH, KELLEY, K. M, ROSENFELD, R. G

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Identification of a Family of Low-Affinity Insulin-Like Growth Factor Binding Proteins (IGFBPs): Characterization of Connective Tissue Growth Factor as a Member of the IGFBP Superfamily by Kim, Ho-Seong, Nagalla, Srinivasa R., Oh, Youngman, Wilson, Elizabeth, Roberts, Charles T., Rosenfeld, Ron G.

“…The insulin-like growth factor (IGF) binding proteins (IGFBPs) modulate the actions of the insulin-like growth factors in endocrine, paracrine, and autocrine…”
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Inhibition of Insulin Receptor Activation by Insulin-like Growth Factor Binding Proteins by Yamanaka, Yoshitaka, Wilson, Elizabeth M., Rosenfeld, Ron G., Oh, Youngman

“…The insulin-like growth factors (IGFs) are transported by a family of high-affinity binding proteins (IGFBPs) that protect IGFs from degradation, limit their…”
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Unraveling Insulin-Like Growth Factor Binding Protein-3 Actions in Human Disease by Jogie-Brahim, Sherryline, Feldman, David, Oh, Youngman

“…The IGF system plays critical roles in somatic growth in an endocrine fashion (somatomedin hypothesis) as well as proliferation and differentiation of normal…”
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Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition by Oh, Y, Müller, H L, Lamson, G, Rosenfeld, R G

“…Estrogen receptor-negative Hs578T human breast cancer cells secrete insulin-like growth factor binding protein (IGFBP)-3 and IGFBP-4 as major binding protein…”
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Demonstration of receptors for insulin-like growth factor binding protein-3 on Hs578T human breast cancer cells by Oh, Y, Müller, H L, Pham, H, Rosenfeld, R G

“…Hs578T human breast cancer cells are from an estrogen receptor-negative breast cell line derived from a highly aggressive mammary tumor. Our previous…”
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