Search Results - "YOUNG, Wise"

Review of lithium effects on brain and blood by Young, Wise

“…Clinicians have long used lithium to treat manic depression. They have also observed that lithium causes granulocytosis and lymphopenia while it enhances…”
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Electrical stimulation and motor recovery by Young, Wise

“…In recent years, several investigators have successfully regenerated axons in animal spinal cords without locomotor recovery. One explanation is that the…”
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Managing Inflammation after Spinal Cord Injury through Manipulation of Macrophage Function by Ren, Yi, Young, Wise

“…Spinal cord injury (SCI) triggers inflammation with activation of innate immune responses that contribute to secondary injury including oligodendrocyte…”
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Spinal cord regeneration by Young, Wise

“…Three theories of regeneration dominate neuroscience today, all purporting to explain why the adult central nervous system (CNS) cannot regenerate. One theory…”
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Species Differences in Blood Lymphocyte Responses After Spinal Cord Injury by Ayala, Carlos, Fishman, Morgan, Noyelle, Margot, Bassiri, Hamid, Young, Wise

“…People with spinal cord injury (SCI) get recurrent infections, such as urinary tract infections (UTIs) and pneumonias, that cause mortality and worsen…”
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Small Organic Compounds Mimicking the Effector Domain of Myristoylated Alanine-Rich C-Kinase Substrate Stimulate Female-Specific Neurite Outgrowth by Tschang, Monica, Kumar, Suneel, Young, Wise, Schachner, Melitta, Theis, Thomas

“…Myristoylated alanine-rich C-kinase substrate (MARCKS) is a critical member of a signaling cascade that influences disease-relevant neural functions such as…”
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Phase I-II Clinical Trial Assessing Safety and Efficacy of Umbilical Cord Blood Mononuclear Cell Transplant Therapy of Chronic Complete Spinal Cord Injury by Zhu, Hui, Poon, Waisang, Liu, Yansheng, Leung, Gilberto Ka-Kit, Wong, Yatwa, Feng, Yaping, Ng, Stephanie C P, Tsang, Kam Sze, Sun, David T F, Yeung, David K, Shen, Caihong, Niu, Fang, Xu, Zhexi, Tan, Pengju, Tang, Shaofeng, Gao, Hongkun, Cha, Yun, So, Kwok-Fai, Fleischaker, Robert, Sun, Dongming, Chen, John, Lai, Jan, Cheng, Wendy, Young, Wise

“…Umbilical cord blood-derived mononuclear cell (UCB-MNC) transplants improve recovery in animal spinal cord injury (SCI) models. We transplanted UCB-MNCs into…”
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Macrophages in spinal cord injury: Phenotypic and functional change from exposure to myelin debris by Wang, Xi, Cao, Kai, Sun, Xin, Chen, Yongxiong, Duan, Zhaoxia, Sun, Li, Guo, Lei, Bai, Paul, Sun, Dongming, Fan, Jianqing, He, Xijing, Young, Wise, Ren, Yi

“…Macrophage activation and persistent inflammation contribute to the pathological process of spinal cord injury (SCI). It was reported that M2 macrophages were…”
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Spinal Microgliosis Due to Resident Microglial Proliferation Is Required for Pain Hypersensitivity after Peripheral Nerve Injury by Gu, Nan, Peng, Jiyun, Murugan, Madhuvika, Wang, Xi, Eyo, Ukpong B., Sun, Dongming, Ren, Yi, DiCicco-Bloom, Emanuel, Young, Wise, Dong, Hailong, Wu, Long-Jun

“…Peripheral nerve injury causes neuropathic pain accompanied by remarkable microgliosis in the spinal cord dorsal horn. However, it is still debated whether…”
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Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury by Nielson, Jessica L., Paquette, Jesse, Liu, Aiwen W., Guandique, Cristian F., Tovar, C. Amy, Inoue, Tomoo, Irvine, Karen-Amanda, Gensel, John C., Kloke, Jennifer, Petrossian, Tanya C., Lum, Pek Y., Carlsson, Gunnar E., Manley, Geoffrey T., Young, Wise, Beattie, Michael S., Bresnahan, Jacqueline C., Ferguson, Adam R.

“…Data-driven discovery in complex neurological disorders has potential to extract meaningful syndromic knowledge from large, heterogeneous data sets to enhance…”
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Quantitative Analysis of SSEA3+ Cells from Human Umbilical Cord after Magnetic Sorting by Leng, Zikuan, Sun, Dongming, Huang, Zihao, Tadmori, Iman, Chiang, Ning, Kethidi, Nikhit, Sabra, Ahmed, Kushida, Yoshihiro, Fu, Yu-Show, Dezawa, Mari, He, Xijing, Young, Wise

“…Multilineage-differentiating stress-enduring (Muse) cells are a population of pluripotent stage-specific embryonic antigen 3 (SSEA3)+ mesenchymal stem cells…”
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Plasma-depleted versus red cell-reduced umbilical cord blood by Young, Wise

“…Umbilical cord blood banks use two methods to store frozen umbilical cord blood (UCB): red cell reduction (RCR) or plasma depletion (PD). The RCR method…”
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Clinical Neurorestorative Therapeutic Guidelines for Spinal Cord Injury (IANR/CANR version 2019) by Huang, Hongyun, Young, Wise, Skaper, Stephen, Chen, Lin, Moviglia, Gustavo, Saberi, Hooshang, Al-Zoubi, Ziad, Sharma, Hari Shanker, Muresanu, Dafin, Sharma, Alok, El Masry, Wagih, Feng, Shiqing

“…Functional restoration after spinal cord injury (SCI) is one of the most challenging tasks in neurological clinical practice. With a view to exploring…”
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Myelin Activates FAK/Akt/NF-κB Pathways and Provokes CR3-Dependent Inflammatory Response in Murine System by Sun, Xin, Wang, Xi, Chen, Tianxiang, Li, Tianyi, Cao, Kai, Lu, Andrew, Chen, Yongxiong, Sun, Dongming, Luo, Jianhong, Fan, Jianqing, Young, Wise, Ren, Yi

“…Inflammatory response following central nervous system (CNS) injury contributes to progressive neuropathology and reduction in functional recovery. Axons are…”
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A consistent, quantifiable, and graded rat lumbosacral spinal cord injury model by Wen, Junxiang, Sun, Dongming, Tan, Jun, Young, Wise

“…The purpose of this study is to develop a rat lumbosacral spinal cord injury (SCI) model that causes consistent motoneuronal loss and behavior deficits. Most…”
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Sex Differences in Immune Cell Infiltration and Hematuria in SCI-Induced Hemorrhagic Cystitis by Askarifirouzjaei, Hadi, Khajoueinejad, Leila, Wei, Elena, Cheruvu, Sruti, Ayala, Carlos, Chiang, Ning, Theis, Thomas, Sun, Dongming, Fazeli, Mehdi, Young, Wise

“…Rats manifest a condition called hemorrhagic cystitis after spinal cord injury (SCI). The mechanism of this condition is unknown, but it is more severe in male…”
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Surgical intervention combined with weight-bearing walking training promotes recovery in patients with chronic spinal cord injury: a randomized controlled study by Zhu, Hui, Guest, James D, Dunlop, Sarah, Xie, Jia-Xin, Gao, Sujuan, Luo, Zhuojing, Springer, Joe E, Wu, Wutian, Young, Wise, Poon, Wai Sang, Liu, Song, Gao, Hongkun, Yu, Tao, Wang, Dianchun, Zhou, Libing, Wu, Shengping, Zhong, Lei, Niu, Fang, Wang, Xiaomei, Liu, Yansheng, So, Kwok-Fai, Xu, Xiao-Ming

“…JOURNAL/nrgr/04.03/01300535-202412000-00032/figure1/v/2024-04-08T165401Z/r/image-tiff For patients with chronic spinal cord injury, the conventional treatment…”
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Rescuing macrophage normal function in spinal cord injury with embryonic stem cell conditioned media by Guo, Lei, Rolfe, Alyssa J, Wang, Xi, Tai, Wenjiao, Cheng, Zhijian, Cao, Kai, Chen, Xiaoming, Xu, Yunsheng, Sun, Dongming, Li, Jinhua, He, Xijing, Young, Wise, Fan, Jianqing, Ren, Yi

“…Macrophages play an important role in the inflammatory responses involved with spinal cord injury (SCI). We have previously demonstrated that infiltrated bone…”
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The 2020 Yearbook of Neurorestoratology by Huang, Hongyun, Chen, Lin, Chopp, Michael, Young, Wise, Robert Bach, John, He, Xijing, Sarnowaska, Anna, Xue, Mengzhou, Chunhua Zhao, Robert, Shetty, Ashok, Siniscalco, Dario, Guo, Xiaoling, Khoshnevisan, Alireza, Hawamdeh, Ziad

“…COVID-19 has been an emerging and rapidly evolving risk to people of the world in 2020. Facing this dangerous situation, many colleagues in Neurorestoratology…”
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Interplay in neural functions of cell adhesion molecule close homolog of L1 (CHL1) and Programmed Cell Death 6 (PDCD6) by Loers, Gabriele, Theis, Thomas, Baixia Hao, Helen, Kleene, Ralf, Arsha, Sanjana, Samuel, Nina, Arsha, Neha, Young, Wise, Schachner, Melitta

“…Close homolog of L1 (CHL1) is a cell adhesion molecule of the immunoglobulin superfamily. It promotes neuritogenesis and survival of neurons in vitro. In vivo,…”
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