Search Results - "YOUNG, Ry"

Bacteriophages and their potential for treatment of gastrointestinal diseases by Duan, Yi, Young, Ry, Schnabl, Bernd

“…Although bacteriophages have been overshadowed as therapeutic agents by antibiotics for decades, the emergence of multidrug-resistant bacteria and a better…”
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Phage spanins: diversity, topological dynamics and gene convergence by Kongari, Rohit, Rajaure, Manoj, Cahill, Jesse, Rasche, Eric, Mijalis, Eleni, Berry, Joel, Young, Ry

“…Spanins are phage lysis proteins required to disrupt the outer membrane. Phages employ either two-component spanins or unimolecular spanins in this final step…”
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Spanin Complex Is Essential for Lambda Lysis by Berry, Joel, Rajaure, Manoj, Pang, Ting, Young, Ry

“…Phage lysis is a ubiquitous biological process, the most frequent cytocidal event in the biosphere. Lysis of Gram-negative hosts has been shown to require…”
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Galaxy and Apollo as a biologist-friendly interface for high-quality cooperative phage genome annotation by Ramsey, Jolene, Rasche, Helena, Maughmer, Cory, Criscione, Anthony, Mijalis, Eleni, Liu, Mei, Hu, James C, Young, Ry, Gill, Jason J

“…In the modern genomic era, scientists without extensive bioinformatic training need to apply high-power computational analyses to critical tasks like phage…”
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Membrane fusion during phage lysis by Rajaure, Manoj, Berry, Joel, Kongari, Rohit, Cahill, Jesse, Young, Ry

“…In general, phages cause lysis of the bacterial host to effect release of the progeny virions. Until recently, it was thought that degradation of the…”
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Rapid de novo evolution of lysis genes in single-stranded RNA phages by Chamakura, Karthik R., Tran, Jennifer S., O’Leary, Chandler, Lisciandro, Hannah G., Antillon, Sophia F., Garza, Kameron D., Tran, Elizabeth, Min, Lorna, Young, Ry

“…Leviviruses are bacteriophages with small single-stranded RNA genomes consisting of 3-4 genes, one of which ( sgl ) encodes a protein that induces the host to…”
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Control of Pierce's Disease by Phage by Das, Mayukh, Bhowmick, Tushar Suvra, Ahern, Stephen J, Young, Ry, Gonzalez, Carlos F

“…Pierce's Disease (PD) of grapevines, caused by Xylella fastidiosa subsp. fastidiosa (Xf), is a limiting factor in the cultivation of grapevines in the US…”
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Bacteriophages of wastewater foaming-associated filamentous Gordonia reduce host levels in raw activated sludge by Liu, Mei, Gill, Jason J., Young, Ry, Summer, Elizabeth J.

“…Filamentous bacteria are a normal and necessary component of the activated sludge wastewater treatment process, but the overgrowth of filamentous bacteria…”
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Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy by Liu, Mei, Hernandez-Morales, Adriana, Clark, James, Le, Tram, Biswas, Biswajit, Bishop-Lilly, Kimberly A., Henry, Matthew, Quinones, Javier, Voegtly, Logan J., Cer, Regina Z., Hamilton, Theron, Schooley, Robert T., Salka, Scott, Young, Ry, Gill, Jason J.

“…In 2016, a 68-year-old patient with a disseminated multidrug-resistant Acinetobacter baumannii infection was successfully treated using lytic bacteriophages…”
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Structural basis of Acinetobacter type IV pili targeting by an RNA virus by Meng, Ran, Xing, Zhongliang, Chang, Jeng-Yih, Yu, Zihao, Thongchol, Jirapat, Xiao, Wen, Wang, Yuhang, Chamakura, Karthik, Zeng, Zhiqi, Wang, Fengbin, Young, Ry, Zeng, Lanying, Zhang, Junjie

“…Acinetobacters pose a significant threat to human health, especially those with weakened immune systems. Type IV pili of acinetobacters play crucial roles in…”
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Systematic and scalable genome-wide essentiality mapping to identify nonessential genes in phages by Piya, Denish, Nolan, Nicholas, Moore, Madeline L, Ramirez Hernandez, Luis A, Cress, Brady F, Young, Ry, Arkin, Adam P, Mutalik, Vivek K

“…Phages are one of the key ecological drivers of microbial community dynamics, function, and evolution. Despite their importance in bacterial ecology and…”
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Spatial and temporal control of lysis by the lambda holin by Cahill, Jesse, Holt, Ashley, Theodore, Matthew, Moreland, Russell, O'Leary, Chandler, Martin, Cody, Bettridge, Kelsey, Xiao, Jie, Young, Ry

“…The infection cycle of phage λ terminates in lysis mediated by three types of lysis proteins, each disrupting a layer in the bacterial envelope: the S105…”
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The Phage T4 Antiholin RI Has a Cleavable Signal Peptide, Not a SAR Domain by Mehner-Breitfeld, Denise, Schwarzkopf, Jan Michel Frederik, Young, Ry, Kondabagil, Kiran, Brüser, Thomas

“…Holin/endolysin-mediated lysis of phage T4 of Escherichia coli is tightly regulated by the antiholins RI and RIII. While regulation by the cytoplasmic RIII…”
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The Essential Escherichia coli Apolipoprotein N-Acyltransferase (Lnt) Exists as an Extracytoplasmic Thioester Acyl-Enzyme Intermediate by Buddelmeijer, Nienke, Young, Ry

“…Escherichia coli apolipoprotein N-acyltransferase (Lnt) transfers an acyl group from sn-1-glycerophospholipid to the free α-amino group of the N-terminal…”
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Characterization of Novel Virulent Broad-Host-Range Phages of Xylella fastidiosa and Xanthomonas by Ahern, Stephen J, Das, Mayukh, Bhowmick, Tushar Suvra, Young, Ry, Gonzalez, Carlos F

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Holin triggering in real time by White, Rebecca, Chiba, Shinobu, Pang, Ting, Dewey, Jill S., Savva, Christos G., Holzenburg, Andreas, Pogliano, Kit, Young, Ry, Collier, R. John

“…During λ infections, the holin S105 accumulates harmlessly in the membrane until, at an allele-specific time, suddenly triggering to form irregular holes of…”
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Visualization of pinholin lesions in vivo by Pang, Ting, Fleming, Tinya C, Pogliano, Kit, Young, Ry

“…Lambdoid phage 21 uses a pinholin–signal anchor release endolysin strategy to effect temporally regulated host lysis. In this strategy, the pinholin S ²¹68…”
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Endolysin Regulation in Phage Mu Lysis by Chamblee, Jake S, Ramsey, Jolene, Chen, Yi, Maddox, Lori T, Ross, Curtis, To, Kam H, Cahill, Jesse L, Young, Ry

“…Bacteriophage Mu is a paradigm coliphage studied mainly because of its use of transposition for genome replication. However, in extensive nonsense mutant…”
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The transcriptional regulator CtrA controls gene expression in Alphaproteobacteria phages: Evidence for a lytic deferment pathway by Mascolo, Elia, Adhikari, Satish, Caruso, Steven M, deCarvalho, Tagide, Folch Salvador, Anna, Serra-Sagristà, Joan, Young, Ry, Erill, Ivan, Curtis, Patrick D

“…Pilitropic and flagellotropic phages adsorb to bacterial pili and flagella. These phages have long been used to investigate multiple aspects of bacterial…”
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Micron-scale holes terminate the phage infection cycle by Dewey, Jill S, Savva, Christos G, White, Rebecca L, Vitha, Stanislav, Holzenburg, Andreas, Young, Ry

“…Holins are small phage-encoded proteins that accumulate harmlessly in the cytoplasmic membrane during the infection cycle until suddenly, at an allele-specific…”
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