Search Results - "YOUNG, Eric D"

Multiscale Optical Ca2+ Imaging of Tonal Organization in Mouse Auditory Cortex by Issa, John B., Haeffele, Benjamin D., Agarwal, Amit, Bergles, Dwight E., Young, Eric D., Yue, David T.

“…Spatial patterns of functional organization, resolved by microelectrode mapping, comprise a core principle of sensory cortices. In auditory cortex,…”
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Neural representation of spectral and temporal information in speech by Young, Eric D

“…Speech is the most interesting and one of the most complex sounds dealt with by the auditory system. The neural representation of speech needs to capture those…”
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First-spike latency information in single neurons increases when referenced to population onset by Chase, Steven M, Young, Eric D

“…It is well known that many stimulus parameters, such as sound location in the auditory system or contrast in the visual system, can modulate the timing of the…”
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A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis by Jin, Yang, Kozan, Darby, Young, Eric D., Hensley, Monica R., Shen, Meng-Chieh, Wen, Jia, Moll, Tabea, Anderson, Jennifer L., Kozan, Hannah, Rawls, John F., Farber, Steven A.

“…Zebrafish are an ideal model organism to study lipid metabolism and to elucidate the molecular underpinnings of human lipid-associated disorders. Unlike murine…”
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What's a cerebellar circuit doing in the auditory system? by Oertel, Donata, Young, Eric D.

“…The shapes of the head and ears of mammals are asymmetrical top-to-bottom and front-to-back. Reflections of sounds from these structures differ with the angle…”
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Reduction of Information Redundancy in the Ascending Auditory Pathway by Chechik, Gal, Anderson, Michael J., Bar-Yosef, Omer, Young, Eric D., Tishby, Naftali, Nelken, Israel

“…Information processing by a sensory system is reflected in the changes in stimulus representation along its successive processing stages. We measured…”
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Linear processing of interaural level difference underlies spatial tuning in the nucleus of the brachium of the inferior colliculus by Slee, Sean J, Young, Eric D

“…The spatial location of sounds is an important aspect of auditory perception, but the ways in which space is represented are not fully understood. No space map…”
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Multiscale mapping of frequency sweep rate in mouse auditory cortex by Issa, John B., Haeffele, Benjamin D., Young, Eric D., Yue, David T.

“…Functional organization is a key feature of the neocortex that often guides studies of sensory processing, development, and plasticity. Tonotopy, which arises…”
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Alignment of sound localization cues in the nucleus of the brachium of the inferior colliculus by Slee, Sean J, Young, Eric D

“…Accurate sound localization is based on three acoustic cues (interaural time and intensity difference and spectral cues from directional filtering by the…”
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Activated MET Is a Molecular Prognosticator and Potential Therapeutic Target for Malignant Peripheral Nerve Sheath Tumors by TORRES, Keila E, ZHU, Quan-Sheng, BELOUSOV, Roman, SUIZHAU WANG, LAHAT, Guy, JUN LIU, HERNANDEZ, Belinda, LAZAR, Alexander J, LEV, Dina, BILL, Katelynn, LOPEZ, Gonzalo, GHADIMI, Markus P, XIANBIAO XIE, YOUNG, Eric D, JUEHUI LIU, NGUYEN, Theresa, BOLSHAKOV, Svetlana

“…MET signaling has been suggested a potential role in malignant peripheral nerve sheath tumors (MPNST). Here, MET function and blockade were preclinically…”
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Uterine Leiomyosarcoma Management, Outcome, and Associated Molecular Biomarkers: A Single Institution’s Experience by Lusby, Kristelle, Savannah, Kari Brewer, Demicco, Elizabeth G., Zhang, Yiqun, Ghadimi, Markus PH, Young, Eric D., Colombo, Chiara, Lam, Ryan, Dogan, Tugce E., Hornick, Jason L., Lazar, Alexander J., Hunt, Kelly K., Anderson, Matthew L., Creighton, Chad J., Lev, Dina, Pollock, Raphael E.

“…Background Uterine leiomyosarcoma (ULMS) is an aggressive, rapidly progressive tumor lacking clinical and molecular predictors of outcome. Methods ULMS…”
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Effects of Unilateral Acoustic Trauma on Tinnitus-Related Spontaneous Activity in the Inferior Colliculus by Ropp, Tessa-Jonne F., Tiedemann, Kerrie L., Young, Eric D., May, Bradford J.

“…This study describes the long-term effects of sound-induced cochlear trauma on spontaneous discharge rates in the central nucleus of the inferior colliculus…”
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Histopathologic features of melanoma in difficult-to-diagnose lesions: A case-control study by Gonzalez, Manuel Lora, MD, Young, Eric D., BS, Bush, James, MD, McKenzie, Katelyn, BS, Hunt, Edgar, MD, Tonkovic-Capin, Viseslav, MD, Jacobs, Melissa, MD, Kucenic, Michael, MD, Fraga, Garth R., MD

“…Background Dermatopathology is considered the gold standard for melanoma diagnosis, but a subset of cases is difficult to diagnose by histopathology. Objective…”
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Cues for Sound Localization Are Encoded in Multiple Aspects of Spike Trains in the Inferior Colliculus by Chase, Steven M, Young, Eric D

“…1 Department of Neurobiology, University of Pittsburgh and Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania; and 2 Center for…”
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An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors by Peng, Tingsheng, Zhang, Pingyu, Liu, Jeffery, Nguyen, Theresa, Bolshakov, Svetlana, Belousov, Roman, Young, Eric D, Wang, Xiaoke, Brewer, Kari, López-Terrada, Delores H, Oliveira, Andre M, Lazar, Alexander J, Lev, Dina

“…Therapeutic progress in well-differentiated/dedifferentiated liposarcoma (WDLPS/DDLPS) is hampered by lack of relevant experimental models, thereby limiting…”
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Histologic variability in solitary fibrous tumors reflects angiogenic and growth factor signaling pathway alterations by Demicco, Elizabeth G., MD, PhD, Wani, Khalida, PhD, Fox, Patricia S., MS, Bassett, Roland L., MS, Young, Eric D., BS, Lev, Dina, MD, Aldape, Kenneth D., MD, Lazar, Alexander J., MD, PhD, Wang, Wei-Lien, MD

“…Summary This study aimed to evaluate expression of receptor tyrosine kinases, their ligands, and mutational status in solitary fibrous tumors, with correlation…”
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Combining EGFR and mTOR Blockade for the Treatment of Epithelioid Sarcoma by XIANBIAO XIE, GHADIMI, Markus P. H, HORNICK, Jason L, LAZAR, Alexander J, LEV, Dina, YOUNG, Eric D, BELOUSOV, Roman, ZHU, Quan-Sheng, JUEHUI LIU, LOPEZ, Gonzalo, COLOMBO, Chiara, TINGSHENG PENG, REYNOSO, David

“…Molecular deregulations underlying epithelioid sarcoma (ES) progression are poorly understood yet critically needed to develop new therapies. Epidermal growth…”
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Proprioceptive Information from the Pinna Provides Somatosensory Input to Cat Dorsal Cochlear Nucleus by Kanold, Patrick O, Young, Eric D

“…The dorsal cochlear nucleus (DCN) is a second-order auditory structure that also receives nonauditory information, including somatosensory inputs from the…”
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Spike-Timing Codes Enhance the Representation of Multiple Simultaneous Sound-Localization Cues in the Inferior Colliculus by Chase, Steven M, Young, Eric D

“…To preserve multiple streams of independent information that converge onto a neuron, the information must be re-represented more efficiently in the neural…”
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Limited Segregation of Different Types of Sound Localization Information among Classes of Units in the Inferior Colliculus by Chase, Steven M, Young, Eric D

“…The auditory system uses three cues to decode sound location: interaural time differences (ITDs), interaural level differences (ILDs), and spectral notches…”
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