Search Results - "YOUNG, Charles Y. F"

Global Methylation Profiling for Risk Prediction of Prostate Cancer by MAHAPATRA, Saswati, KLEE, Eric W, YOUNG, Charles Y. F, ZHIFU SUN, JIMENEZ, Rafael E, KLEE, George G, TINDALL, Donald J, VANAJA DONKENA, Krishna

“…The aim of this study was to investigate the promoter hypermethylation as diagnostic markers to detect malignant prostate cells and as prognostic markers to…”
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Suppression of the androgen receptor function by quercetin through protein-protein interactions of Sp1, c-Jun, and the androgen receptor in human prostate cancer cells by Yuan, Huiqing, Young, Charles Y. F, Tian, Yuanyuan, Liu, Zhifang, Zhang, Mengye, Lou, Hongxiang

“…We have previously reported that the increase in c-Jun expression induced by quercetin inhibited androgen receptor (AR) transactivation, and Sp1 was involved…”
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Phenethyl isothiocyanate inhibits androgen receptor-regulated transcriptional activity in prostate cancer cells through suppressing PCAF by Yu, Chunguang, Gong, Ai-Yu, Chen, Dongqing, Solelo Leon, Daniel, Young, Charles YF, Chen, Xian-Ming

“…Scope Androgen receptor (AR) signaling is critical for all aspects of prostate growth and tumorigenesis. The glucosinolate‐derived phenethyl isothiocyanate…”
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Differential regulation of MMPs by E2F1, Sp1 and NF-kappa B controls the small cell lung cancer invasive phenotype by Li, Zunling, Guo, Yanxia, Jiang, Hanming, Zhang, Tingguo, Jin, Changzhu, Young, Charles Y F, Yuan, Huiqing

“…E2F1 transcription factor plays a vital role in the regulation of diverse cellular processes including cell proliferation, apoptosis, invasion and metastasis…”
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PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer by DONKENA KRISHNA VANAJA, BALLMAN, Karla V, MORLAN, Bruce W, CHEVILLE, John C, NEUMANN, Roxann M, LIEBER, Michael M, TINDALL, Donald J, YOUNG, Charles Y. F

“…PURPOSE: We analyzed the expression of genes to identify reliable molecular markers in the diagnosis and progression of prostate cancer. EXPERIMENTAL DESIGN:…”
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Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells by Xi, Guangmin, Hu, Xiaoyan, Wu, Baolin, Jiang, Hanming, Young, Charles Y.F, Pang, Yingxin, Yuan, Huiqing

“…Abstract Paclitaxel has been demonstrated to be an effective mitotic inhibitor and apoptosis inducer to treat aggressive malignancies. In this paper, we have…”
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Sesquiterpenoids from myrrh inhibit androgen receptor expression and function in human prostate cancer cells by Wang, Xiao-ling, Kong, Feng, Shen, Tao, Young, Charles YF, Lou, Hong-xiang, Yuan, Hui-qing

“…Aim： To examine whether two naturally occurring sesquiterpenoids （ST1 and ST2） with anti-proliferative activity in prostate cancer cells inhibit androgen…”
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Knockdown of AGR2 induces cellular senescence in prostate cancer cells by ZHONGYI HU, YUANYUAN GU, BO HAN, JINSAN ZHANG, ZUNLING LI, KELI TIAN, YOUNG, Charles Y. F, HUIQING YUAN

“…Anterior-gradient 2 (AGR2), overexpressed in many tumors including prostate cancer (PCa), is implicated in stimulation of cell proliferation, adhesion,…”
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Oxidative Stress and DNA Methylation in Prostate Cancer by Donkena, Krishna Vanaja, Young, Charles Y. F., Tindall, Donald J.

“…The protective effects of fruits, vegetables, and other foods on prostate cancer may be due to their antioxidant properties. An imbalance in the oxidative…”
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Retigeric acid B exhibits antitumor activity through suppression of nuclear factor-κB signaling in prostate cancer cells in vitro and in vivo by Liu, Yong-Qing, Hu, Xiao-Yan, Lu, Tao, Cheng, Yan-Na, Young, Charles Y F, Yuan, Hui-Qing, Lou, Hong-Xiang

“…Previously, we reported that retigeric acid B (RB), a natural pentacyclic triterpenic acid isolated from lichen, inhibited cell growth and induced apoptosis in…”
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A Phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma by Jatoi, Aminah, Ellison, Neil, Burch, Patrick A., Sloan, Jeff A., Dakhil, Shaker R., Novotny, Paul, Tan, Winston, Fitch, Tom R., Rowland, Kendrith M., Young, Charles Y. F., Flynn, Patrick J.

“…BACKGROUND Recent laboratory and epidemiologic studies have suggested that green tea has antitumor effects in patients with prostate carcinoma. This Phase II…”
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AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer by Zhang, Jin-San, Gong, Aiyu, Cheville, John C., Smith, David I., Young, Charles Y. F.

“…AGR2, the human homologue of Xenopus anterior gradient 2 (XAG2), was identified by a suppression subtractive hybridization‐based technique as an…”
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Inhibitory effect of acetyl-11-keto-β-boswellic acid on androgen receptor by interference of Sp1 binding activity in prostate cancer cells by Yuan, Hui-Qing, Kong, Feng, Wang, Xiao-Ling, Young, Charles Y.F., Hu, Xiao-Yan, Lou, Hong-Xiang

“…Androgen receptor (AR)-mediated signaling is crucial for the development and progression of prostate cancer (PCa). Naturally occurring phytochemicals that…”
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Induction of DNA damage and ATF3 by retigeric acid B, a novel topoisomerase II inhibitor, promotes apoptosis in prostate cancer cells by Liu, Yongqing, Gao, Fengbin, Jiang, Hanming, Niu, Leilei, Bi, Yiling, Young, Charles Y.F, Yuan, Huiqing, Lou, Hongxiang

“…Highlights • Retigeric acid B inhibits activity of topoisomerase IIα. • Retigeric acid B triggers cell death by inducing DNA damage and locking DNA damage…”
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Riccardin D Exerts Its Antitumor Activity by Inducing DNA Damage in PC-3 Prostate Cancer Cells In Vitro and In Vivo by Hu, Zhongyi, Kong, Feng, Si, Manfei, Tian, Keli, Yu, Lin Xi, Young, Charles Y F, Yuan, Huiqing, Lou, Hongxiang

“…We recently reported that Riccardin D (RD) was able to induce apoptosis by targeting Topo II. Here, we found that RD induced cell cycle arrest in G2/M phase in…”
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Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells by Gong, Aiyu, He, Meilan, Krishna Vanaja, Donkena, Yin, Ping, Karnes, R. Jeffrey, Young, Charles Y.F

“…This study was undertaken to investigate the mechanism by which phenethyl isothiocyanate (PEITC), a natural compound from cruciferous vegetables, exhibits…”
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miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells by Gong, Ai-Yu, Eischeid, Alex N, Xiao, Jing, Zhao, Jian, Chen, Dongqing, Wang, Zhao-Yi, Young, Charles Yf, Chen, Xian-Ming

“…Androgen receptor (AR) signalling is critical to the initiation and progression of prostate cancer (PCa). Transcriptional activity of AR involves chromatin…”
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Jungermannenone A and B induce ROS- and cell cycle-dependent apoptosis in prostate cancer cells in vitro by Guo, Yan-xia, Lin, Zhao-min, Wang, Mei-juan, Dong, Yi-wen, Niu, Huan-min, Young, Charles YF, Lou, Hong-xiang, Yuan, Hui-qing

“…Aim, Jungermannenone A and B （JA, JB） are new ent-kaurane diterpenoids isolated from Chinese liverwort Jungermannia fauriana, which show anti-proliferation…”
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Gum mastic inhibits the expression and function of the androgen receptor in prostate cancer cells by He, Mei‐Lan, Yuan, Hui‐Qing, Jiang, An‐Li, Gong, Ai Yu, Chen, Wei‐Wen, Zhang, Peng‐Ju, Young, Charles Y. F., Zhang, Jian‐Ye

“…Accumulating evidence suggests that the androgen receptor (AR) may play an important role in the development and progression of prostate cancer. To find new,…”
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A novel anticancer agent, retigeric acid B, displays proliferation inhibition, S phase arrest and apoptosis activation in human prostate cancer cells by Liu, Han, Liu, Yi-qing, Liu, Yong-qing, Xu, Ai-hui, Young, Charles Y.F., Yuan, Hui-qing, Lou, Hong-xiang

“…Retigeric acid B (RB), a naturally occurring pentacyclic triterpenic acid, has been noted for its antifungal properties in vitro. Here, we observed that RB…”
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