Search Results - "YOUINOU, Pierre"

Haralampos M. Moutsopoulos: A lifetime in autoimmunity by Youinou, Pierre

“…Abstract Three years ago, the Journal of Autoimmunity and Autoimmunity Reviews launched a series of special issues devoted to the contributions of outstanding…”
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Disturbance of cytokine networks in Sjögren's syndrome by Youinou, Pierre, Pers, Jacques-Olivier

“…The difficulty in predicting the consequences of interactions between different cytokine networks has increased with the expansion of the T helper (Th) cell…”
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Contribution of salivary gland ultrasonography to the diagnosis of Sjögren's syndrome: Toward new diagnostic criteria? by Cornec, Divi, Jousse‐Joulin, Sandrine, Pers, Jacques‐Olivier, Marhadour, Thierry, Cochener, Béatrice, Boisramé‐Gastrin, Sylvie, Nowak, Emmanuel, Youinou, Pierre, Saraux, Alain, Devauchelle‐Pensec, Valérie

“…Objective To determine the accuracy of salivary gland ultrasonography (SGUS) for diagnosing primary Sjögren's syndrome (SS) and to suggest modifications of the…”
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Human regulatory B cells control the TFH cell response by Achour, Achouak, PhD, Simon, Quentin, PhD, Mohr, Audrey, MSc, Séité, Jean-François, PhD, Youinou, Pierre, MD, PhD, Bendaoud, Boutahar, PharmD, Ghedira, Ibtissem, PharmD, PhD, Pers, Jacques-Olivier, DDS, PhD, Jamin, Christophe, PhD

“…Background Follicular helper T (TFH ) cells support terminal B-cell differentiation. Human regulatory B (Breg) cells modulate cellular responses, but their…”
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Epigenetics and Autoimmunity, with Special Emphasis on Methylation by Renaudineau, Yves, Youinou, Pierre

“…Epigenetics signifies stable and heritable changes in gene expression without changes in the genetic code. There is a wealth of emerging evidence for such…”
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A case for IL-6, IL-17A, and nitric oxide in the pathophysiology of Sjögren’s syndrome by Benchabane, Sarah, Boudjelida, Abdelhalim, Toumi, Ryma, Belguendouz, Houda, Youinou, Pierre, Touil-Boukoffa, Chafia

“…Sjögren’s syndrome (SS) is an autoimmune epithelitis characterized by mononuclear cell (MNC) infiltration of the lacrimal and salivary glands (SG), as well as…”
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Maturation and function of human dendritic cells are regulated by B lymphocytes by Morva, Ahsen, Lemoine, Sébastien, Achour, Achouak, Pers, Jacques-Olivier, Youinou, Pierre, Jamin, Christophe

“…Mature dendritic cells (DCs) are stimulators of T-cell immune response, whereas immature DCs support T-cell tolerance. Murine B cells can inhibit the…”
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IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes by Séïté, Jean-François, Cornec, Divi, Renaudineau, Yves, Youinou, Pierre, Mageed, Rizgar A., Hillion, Sophie

“…Among various mechanisms for interactions with B cells, intravenous immunoglobulin (IVIg) may operate through the insertion of its Fc part into the Fc-γ…”
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TLR2 Is One of the Endothelial Receptors for β2-Glycoprotein I by Alard, Jean-Eric, Gaillard, Fanny, Daridon, Capucine, Shoenfeld, Yehuda, Jamin, Christophe, Youinou, Pierre

“…Abstract During the antiphospholipid syndrome, β2-gpI interacts with phospholipids on endothelial cell (EC) surface to allow the binding of autoantibodies…”
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Concentrations of BAFF Correlate with Autoantibody Levels, Clinical Disease Activity, and Response to Treatment in Early Rheumatoid Arthritis by BOSELLO, Silvia, YOUINOU, Pierre, DARIDON, Capucine, TOLUSSO, Barbara, BENDAOUD, Boutahar, PIETRAPERTOSA, Donatello, MORELLI, Alessia, FERRACCIOLI, Gianfranco

“…Objective To determine whether levels of B cell activating factor (BAFF), a member of the tumor necrosis factor family, relate to autoantibody levels, disease…”
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Intravenous immunoglobulin induces a functional silencing program similar to anergy in human B cells by Séïté, Jean-François, PhD, Goutsmedt, Carole, MSc, Youinou, Pierre, MD, PhD, Pers, Jacques-Olivier, DDS, PhD, Hillion, Sophie, PhD

“…Background Chronic inflammatory and autoimmune diseases are largely due to inappropriate response of hyperactive or autoreactive B cells. These autoreactive B…”
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TLR9 drives the development of transitional B cells towards the marginal zone pathway and promotes autoimmunity by Guerrier, Thomas, Youinou, Pierre, Pers, Jacques-Olivier, Jamin, Christophe

“…Abstract Maturation of B cells depends on environmental stimuli. Peripheral immature B cells develop into follicular pathway when antigenic stimulation is…”
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B-cell tolerance breakdown in Sjögren's Syndrome: Focus on BAFF by Varin, Marie-Michèle, Le Pottier, Laëtitia, Youinou, Pierre, Saulep, Damien, Mackay, Fabienne, Pers, Jacques-Olivier

“…Abstract Sjögren's syndrome (SS) is an autoimmune epithelitis hallmarked by a destruction of epithelial cells, the subsequent lymphocytic infiltration of…”
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The paradox of CD5-expressing B cells in systemic lupus erythematosus by Youinou, Pierre, Renaudineau, Yves

“…Abstract The pathophysiological relevance of B cells for systemic lupus erythematosus (SLE), particularly those expressing the T-cell marker CD5, raises the…”
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A comprehensive evaluation of serum autoantibodies in primary biliary cirrhosis by Agmon-Levin, Nancy, Shapira, Yinon, Selmi, Carlo, Barzilai, Ori, Ram, Maya, Szyper-Kravitz, Martine, Sella, Sara, Katz, Bat-sheva Porat, Youinou, Pierre, Renaudineau, Yves, Larida, Bruno, Invernizzi, Pietro, Gershwin, M. Eric, Shoenfeld, Yehuda

“…Abstract In primary biliary cirrhosis (PBC) serum markers other than anti-mitochondrial antibodies (AMA) are promising in terms of disease severity and…”
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B-lymphocytes govern the pathogenesis of Sjögren's syndrome by Youinou, Pierre, Saraux, Alain, Pers, Jacques-Olivier

“…T cells have originally occupied central stage of the debate on the type of lymphocytes governing the pathogenesis of Sjögren's syndrome (SS). However, B cells…”
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IL-6 Contributes to the Expression of RAGs in Human Mature B Cells by Hillion, Sophie, Dueymes, Maryvonne, Youinou, Pierre, Jamin, Christophe

“…Mature B cells acquire the capacity to revise rearranged Ig V region genes in secondary lymphoid organs. In previous studies, we demonstrated that…”
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Autoantibodies to endothelial cell surface ATP synthase, the endogenous receptor for hsp60, might play a pathogenic role in vasculatides by Alard, Jean-Eric, Hillion, Sophie, Guillevin, Loïc, Saraux, Alain, Pers, Jacques-Olivier, Youinou, Pierre, Jamin, Christophe

“…Heat shock protein (hsp) 60 that provides "danger signal" binds to the surface of resting endothelial cells (EC) but its receptor has not yet been…”
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Neurological Disorders in Primary Sjögren's Syndrome by Tobón, Gabriel J., Pers, Jacques-Olivier, Devauchelle-Pensec, Valérie, Youinou, Pierre

“…Sjögren's syndrome is an autoimmune disease characterized by an autoimmune exocrinopathy involving mainly salivary and lacrimal glands. The histopathological…”
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Geographic Location Determines Differentially Methylated Gene Expressions in Autoimmune Diseases by Pers, Jacques-Olivier, Bahane, Hajar, Le Dantec, Christelle, Foulquier, Nathan, Alarcon-Riquelme, Marta E., Youinou, Pierre

“…Further observations support the role of environmental factors in autoimmune diseases via the alteration of the epigenetic machinery. In this context,…”
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