Search Results - "YOSHIDA, J"

Applications of patient-derived tumor xenograft models and tumor organoids by Yoshida, Go J

“…Patient-derived tumor xenografts (PDXs), in which tumor fragments surgically dissected from cancer patients are directly transplanted into immunodeficient…”
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Regulation of heterogeneous cancer-associated fibroblasts: the molecular pathology of activated signaling pathways by Yoshida, Go J

“…Accumulating evidence indicates that intratumoral heterogeneity contributes to the development of resistance to anticancer therapeutics. Fibroblasts, which are…”
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Metabolic reprogramming: the emerging concept and associated therapeutic strategies by Yoshida, Go J

“…Tumor tissue is composed of cancer cells and surrounding stromal cells with diverse genetic/epigenetic backgrounds, a situation known as intra-tumoral…”
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Emerging roles of Myc in stem cell biology and novel tumor therapies by Yoshida, Go J

“…The pathophysiological roles and the therapeutic potentials of Myc family are reviewed in this article. The physiological functions and molecular machineries…”
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Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment by Yoshida, Go J

“…The 2016 Nobel Prize in Physiology or Medicine was awarded to the researcher that discovered autophagy, which is an evolutionally conserved catabolic process…”
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Therapeutic strategies targeting cancer stem cells by Yoshida, Go J., Saya, Hideyuki

“…Cancer stem cells (CSCs) are undifferentiated cancer cells with a high tumorigenic activity, the ability to undergo self‐renewal, and a multilineage…”
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Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies by Yoshida, Go J, Azuma, Arata, Miura, Yukiko, Orimo, Akira

“…Neoplastic epithelial cells coexist in carcinomas with various non-neoplastic stromal cells, together creating the tumor microenvironment. There is a growing…”
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Study on Reduction of Quench Recovery Time by Inductive Energy Extraction by Ebara, Y., Yoshida, J.

“…Superconducting coils can generate high magnetic fields and are used in many applications in medicine, industry and research. A superconducting coil stores…”
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Beyond the Warburg Effect: N-Myc Contributes to Metabolic Reprogramming in Cancer Cells by Yoshida, Go J.

“…Cancer cells generate large amounts of lactate derived from glucose regardless of the available oxygen level. Cancer cells finely control ATP synthesis by…”
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The therapeutic strategy of drug re-positioning to induce autophagic cell death in brain malignancy by Yoshida, Go J.

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How to eliminate MYCN-positive hepatic cancer stem cells to prevent the recurrence? by Yoshida, Go J.

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Emerging role of epithelial-mesenchymal transition in hepatic cancer by Yoshida, Go J

“…Accumulating evidence suggests that the phenomenon of epithelial-mesenchymal-transition (EMT) plays a fundamental role in the tumor development. Several…”
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Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation by Yoshida, Go J., Saya, Hideyuki

“…•CD44 variant8–10 and c-Myc are inversely expressed in gastric cancer cells.•Redox-stress enhances c-Myc expression via canonical Wnt signal.•CD44v, but not…”
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The Harmonious Interplay of Amino Acid and Monocarboxylate Transporters Induces the Robustness of Cancer Cells by Yoshida, Go J

“…There is a growing body of evidence that metabolic reprogramming contributes to the acquisition and maintenance of robustness associated with malignancy. The…”
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A case of mandibular ameloblastoma with pulmonary metastasis 31years after resection ∼comparing pathological images original and metastatic lesions by Yoshida, J

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Molecular pathology underlying the robustness of cancer stem cells by Yoshida, Go J., Saya, Hideyuki

“…Intratumoral heterogeneity is tightly associated with the failure of anticancer treatment modalities including conventional chemotherapy, radiation therapy,…”
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Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell by Yae, Toshifumi, Tsuchihashi, Kenji, Ishimoto, Takatsugu, Motohara, Takeshi, Yoshikawa, Momoko, Yoshida, Go J., Wada, Takeyuki, Masuko, Takashi, Mogushi, Kaoru, Tanaka, Hiroshi, Osawa, Tsuyoshi, Kanki, Yasuharu, Minami, Takashi, Aburatani, Hiroyuki, Ohmura, Mitsuyo, Kubo, Akiko, Suematsu, Makoto, Takahashi, Kazuhisa, Saya, Hideyuki, Nagano, Osamu

“…In cancer metastasis, various environmental stressors attack the disseminating cells. The successful colonization of cancer cells in secondary sites therefore…”
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A National Cancer Database Analysis of Radiofrequency Ablation versus Stereotactic Body Radiotherapy in Early-Stage Non–Small Cell Lung Cancer by Lam, Alexander, Yoshida, Emi J., Bui, Kevin, Fernando, Dayantha, Nelson, Kari, Abi-Jaoudeh, Nadine

“…To compare overall survival (OS) after radiofrequency (RF) ablation and stereotactic body radiotherapy (SBRT) at high-volume centers in patients with…”
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EpCAM expression in the prostate cancer makes the difference in the response to growth factors by Yoshida, Go J., Saya, Hideyuki

“…•EpCAM is heterogeneously expressed in prostate cancer both in vitro and in vivo.•mTOR signaling is differentially regulated in EpCAM-high and -low…”
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Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial by Gillespie, Erin F, Yang, Joanna C, Mathis, Noah J, Marine, Catherine B, White, Charlie, Zhang, Zhigang, Barker, Christopher A, Kotecha, Rupesh, McIntosh, Alyson, Vaynrub, Max, Bartelstein, Meredith K, Mitchell, Aaron, Guttmann, David M, Yerramilli, Divya, Higginson, Daniel S, Yamada, Yoshida J, Kohutek, Zachary A, Powell, Simon N, Tsai, Jillian, Yang, Jonathan T

“…External-beam radiation therapy (RT) is standard of care (SOC) for pain relief of symptomatic bone metastases. We aimed to evaluate the efficacy of radiation…”
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