Search Results - "YOON, Seitetsu"

Significance of post‐progression therapy after tyrosine kinase inhibitors for advanced hepatocellular carcinoma by Yano, Yoshihiko, Yamamoto, Atsushi, Minami, Akihiro, Momose, Kenji, Mimura, Takuya, Kim, Soo Ki, Hayashi, Hiroki, Kado, Takuo, Hirano, Hirotaka, Hirohata, Seiya, Yoon, Seitetsu, Nishi, Katsuhisa, Tei, Hiroshi, Tanaka, Hidenori, Oouchi, Sachiko, Matsuura, Takanori, Yasutomi, Eiichiro, Hatazawa, Yuri, Shiomi, Yuuki, Ueda, Yoshihide, Kodama, Yuzo

“…Background and Aim Molecular‐targeted therapies such as sorafenib and lenvatinib have long been used as first‐line treatment for advanced hepatocellular…”
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Factors associated with the response to atezolizumab/bevacizumab combination therapy for hepatocellular carcinoma by Yano, Yoshihiko, Yamamoto, Atsushi, Mimura, Takuya, Kushida, Saeko, Hirohata, Seiya, Yoon, Seitetsu, Hirano, Hirotaka, Kim, Soo Ki, Hatazawa, Yuri, Momose, Kenji, Hayashi, Hiroki, Kado, Takuo, Nishi, Katsuhisa, Tanaka, Hidenori, Matsuura, Takanori, Yoshida, Ryutaro, Asaji, Naoki, Yasutomi, Eiichiro, Shiomi, Yuuki, Minami, Akihiro, Komatsu, Shohei, Fukumoto, Takumi, Ueda, Yoshihide, Kodama, Yuzo

“…Background and Aim The purpose of this study was to analyze factors associated with the overall survival (OS) of atezolizumab/bevacizumab combination therapy…”
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Sequence heterogeneity in NS5A of hepatitis C virus genotypes 2a and 2b and clinical outcome of pegylated-interferon/ribavirin therapy by El-Shamy, Ahmed, Shoji, Ikuo, Kim, Soo-Ryang, Ide, Yoshihiro, Imoto, Susumu, Deng, Lin, Yoon, Seitetsu, Fujisawa, Takashi, Tani, Satoshi, Yano, Yoshihiko, Seo, Yasushi, Azuma, Takeshi, Hotta, Hak

“…Pegylated-interferon plus ribavirin (PEG-IFN/RBV) therapy is a current standard treatment for chronic hepatitis C. We previously reported that the viral…”
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Mutational diversity of NS5A and NS3 during triple therapy (telaprevir, pegylated-interferon-α 2b and ribavirin) for genotype 1b chronic hepatitis C: The Kobe Hepatitis Therapeutic Group by BAI, FUGUI, YANO, YOSHIHIKO, KIM, SOO-RYANG, SEO, YASUSHI, MIKI, AKIRA, SAITO, MASAYA, HIRANO, HIROTAKA, MOMOSE, KENJI, MINAMI, AKIHIRO, HATAZAWA, YURI, HAYAKUMO, TAKANOBU, WIDASARI, DEWIYANI INDAH, RINONCE, HANGGORO TRI, SUGANO, MASAHIKO, TANI, SATOSHI, YOON, SEITETSU, IMOTO, SUSUMU, AZUMA, TAKESHI, HOTTA, HAK, HAYASHI, YOSHITAKE

“…Telaprevir, a non-structural (NS)3/4A protease inhibitor, is a direct-acting antiviral drug that inhibits viral replication. Triple therapy with telaprevir,…”
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Downregulation of stomach cancer-associated protein tyrosine phosphatase-1 (SAP-1) in advanced human hepatocellular carcinoma by NAGANO, Hidenobu, NOGUCHI, Tetsuya, INAGAKI, Kenjiro, YOON, Seitetsu, MATOZAKI, Takashi, ITOH, Hiroshi, KASUGA, Masato, HAYASHI, Yoshitake

“…SAP-1 (stomach cancer-associated protein tyrosine phosphatase-1) is a transmembrane-type protein tyrosine phosphatase that has been implicated as a negative…”
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Comparative Sequence Analysis of the Core Protein and Its Frameshift Product, the F Protein, of Hepatitis C Virus Subtype 1b Strains Obtained from Patients with and without Hepatocellular Carcinoma by OGATA, Satoshi, NAGANO-FUJII, Motoko, YONSON KU, YOON, Seitetsu, HOTTA, Hak

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Identification of Hepatitis C Virus (HCV) Subtype 1b Strains That Are Highly, or Only Weakly, Associated with Hepatocellular Carcinoma on the Basis of the Secondary Structure of an Amino-Terminal Portion of the HCV NS3 Protein by OGATA, Satoshi, FLORESE, Ruth Huab, NAGANO-FUJII, Motoko, HIDAJAT, Rachmat, LIN DENG, YONSON KU, YOON, Seitetsu, SAITO, Takafumi, KAWATA, Sumio, HOTTA, Hak

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Correlation between Secondary Structure of an Amino-Terminal Portion of the Nonstructural Protein 3 (NS3) of Hepatitis C Virus and Development of Hepatocellular Carcinoma by Ogata, Satoshi, Ku, Yonson, Yoon, Seitetsu, Makino, Shigeru, Nagano-Fujii, Motoko, Hotta, Hak

“…Correlation between sequence variation of hepatitis C virus (HCV) and development of hepatocellular carcinoma (HCC) has not yet been demonstrated. In the…”
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Primary Presacral Neuroendocrine Tumor Presenting as Multiple Liver Metastasis: A Case Report by Watanabe, Takafumi, Yoon, Seitetsu, Yamakawa, Kohei, Hyodo, Toshiki, Izaki, Kenta, Okada, Hirofumi, Shirakawa, Yutaka, Ebisutani, Chikara, Sakamoto, Yoshio, Hirohata, Shigeya

“…BACKGROUND Various neoplasms, including neuroendocrine neoplasms (NENs), can arise from the presacral space. Most presacral lesions are detected due to…”
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In situ demonstration of parathyroid hormone-related protein mRNA in sclerosing hepatic carcinoma by KITAZAWA, R, KITAZAWA, S, YOON, S, KASUGA, M, MAEDA, S

“…A 69-year-old man had a hepatic tumour occupying the left and half of the right lobe, with portal vein thrombus. There were hypercalcaemia and…”
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A case of well-differentiated hepatocellular carcinoma arising in primary biliary cirrhosis by Yano, Yoshihiko, Yoon, Seitetsu, Seo, Yasushi, Ninomiya, Toshiaki, Nagano, Hidenobu, Nakaji, Miyuki, Hayashi, Yoshitake, Kasuga, Masato

“…Primary biliary cirrhosis (PBC) is a chronic progressive, autoimmune liver disease that increases the risk of hepatobiliary malignancies at a late stage. We…”
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Serum IFN-λ3 Levels Correlate with Serum Hepatitis C Virus RNA Levels in Symptomatic Patients with Acute Hepatitis C by Imoto, Susumu, Kim, Soo Ryang, Amano, Keisuke, Iio, Etsuko, Yoon, Seitetsu, Hirohata, Shigeya, Yano, Yoshihiko, Ishikawa, Toru, Katsushima, Shinji, Komeda, Toshiki, Fukunaga, Toyokazu, Chung, Hobyung, Kokuryu, Hiroyuki, Horie, Yutaka, Hatae, Takashi, Fujinami, Aya, Kim, Soo Ki, Kudo, Masatoshi, Tanaka, Yasuhito

“…Recent genome-wide association studies demonstrated that 2 single nucleotide polymorphisms (SNPs), upstream of the interferon-λ (IFNL) 3 gene, are associated…”
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Prediction of efficacy of interferon treatment of chronic hepatitis C by multivariate analysis and a new classification by Kim, Soo Ryang, Hayashi, Yoshitake, Yoon, Seitetsu, Taniguchi, Miyuki, Yang, Moo Kwan, Kim, Ke Ih, Kim, Myung Mi, Saeki, Keizo, Nukata, Isao, Imoto, Susumu

“…One hundred and fifteen patients with chronic hepatitis C were administered interferon (IFN) and classed into two groups: (i) complete responders (CR), HCV‐RNA…”
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Factors associated with the decrease in hepatitis B surface antigen titers following interferon therapy in patients with chronic hepatitis B: Is interferon and adefovir combination therapy effective? by Yano, Yoshihiko, Seo, Yasushi, Hayashi, Hiroki, Hatazawa, Yuri, Hirano, Hirotaka, Minami, Akihiro, Kawano, Yuki, Saito, Masaya, Ninomiya, Toshiaki, Sugano, Masahiko, Yamada, Hajime, Kitajima, Naoto, Yoon, Seitetsu, Hayashi, Yoshitake

“…The purpose of antiviral therapy in chronic hepatitis B (CHB) is generally to achieve a decrease and ultimately disappearance of HBs antigen (HBsAg)…”
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Comparative evaluation of serum HCV RNA by Roche Monitor Assay. Versions 1.0 and 2.0; as a predictive marker of subsequent response to IFN therapy by Takenokuchi, Mariko, Yasuda, Chie, Nakamachi, Yuji, Mukai, Masahiko, Yoon, Seitetsu, Kondoh, Shinichi, Kumagai, Shunichi

“…Quantitative measurement of serum hepatitis C virus(HCV) RNA is important in predicting and monitoring interferon(IFN) therapy. We compared the sensitivity of…”
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Identification of Hepatitis C Virus Subtype 3b (HCV-3b) among Japanese Patients with Liver Diseases Using Highly Efficient Primers for Reverse Transcription-Polymerase Chain Reaction by Doi, Hisaya, Yoon, Seitetsu, Homma, Morio, Hotta, Hak

“…With a reverse transcription-polymerase chain reaction method that utilized highly efficient primers, the NS5 region of hepatitis C virus (HCV) genome could be…”
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Mutational diversity of NS5A and NS3 during triple therapy for genotype1b chronic hepatitis C: The Kobe Hepatitis Therapeutic Group by Bai, Fugui, Yano, Yoshihiko, Kim, Soo-Ryang, Seo, Yasushi, Miki, Akira, Saito, Masaya, Hirano, Hirotaka, Momose, Kenji, Minami, Akihiro, Hatazawa, Yuri, Hayakumo, Takanobu, Widasari, Dewiyani Indah, Rinonce, Hanggoro Tri, Sugano, Masahiko, Tani, Satoshi, Yoon, Seitetsu, Imoto, Susumu, Azuma, Takeshi, Hotta, Hak, Hayashi, Yoshitake

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Mutations in non-structural 5A and rapid viral response to pegylated interferon-α-2b plus ribavirin therapy are associated with therapeutic efficacy in patients with genotype 1b chronic hepatitis C by YANO, YOSHIHIKO, SEO, YASUSHI, MIKI, AKIRA, SAITO, MASAYA, KATO, HIROTAKA, HAMANO, KEN-ICHI, OYA, MANABU, OUCHI, SACHIKO, FUJISAWA, TAKASHI, YAMADA, HAJIME, YAMASHITA, YUKIMASA, TANI, SATOSHI, HIROHATA, SHIGEYA, YOON, SEITETSU, KITAJIMA, NAOTO, KITAGAKI, KAZUNARI, KAWARA, AKIRA, NAKASHIMA, TAKATOSHI, YU, HOSAI, MAEDA, TETSUO, AZUMA, TAKESHI, EL-SHAMY, AHMED, HOTTA, HAK, HAYASHI, YOSHITAKE

“…For patients chronically infected with hepatitis C virus (HCV), mutations in the non-structural 5A (NS5A) gene are important predictive factors for the…”
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IFN-alpha prevents the growth of pre-neoplastic lesions and inhibits the development of hepatocellular carcinoma in the rat by Nakaji, Miyuki, Yano, Yoshihiko, Ninomiya, Toshiaki, Seo, Yasushi, Hamano, Kenichi, Yoon, Seitetsu, Kasuga, Masato, Teramoto, Tadahisa, Hayashi, Yoshitake, Yokozaki, Hiroshi

“…Interferon (IFN)-alpha treatment is a common therapy for chronic viral hepatitis and contributes to preventing hepatocarcinogenesis. However, it is not clear…”
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Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-1 (E-NPP1/PC-1) and -3 (E-NPP3/CD203c/PD-Iβ/B10/gp130 RB13-6) in inflammatory and neoplastic bile duct diseases by Yano, Yoshihiko, Hayashi, Yoshitake, Sano, Kimihiko, Nagano, Hidenobu, Nakaji, Miyuki, Seo, Yasushi, Ninomiya, Toshiaki, Yoon, Seitetsu, Yokozaki, Hiroshi, Kasuga, Masato

“…Ecto-nucleotide pyrophosphatase/phosphodiesterase-I enzyme (E-NPP) consists of three closely related molecules: E-NPP1, E-NPP2 and E-NPP3. We investigated the…”
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