Search Results - "YONGPING CUI"

Overcoming cancer therapeutic bottleneck by drug repurposing by Zhang, Zhe, Zhou, Li, Xie, Na, Nice, Edouard C., Zhang, Tao, Cui, Yongping, Huang, Canhua

“…Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated the development of the alternative strategy of drug repurposing, the…”
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Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma by Yan, Ting, Cui, Heyang, Zhou, Yong, Yang, Bin, Kong, Pengzhou, Zhang, Yingchun, Liu, Yiqian, Wang, Bin, Cheng, Yikun, Li, Jiayi, Guo, Shixing, Xu, Enwei, Liu, Huijuan, Cheng, Caixia, Zhang, Ling, Chen, Ling, Zhuang, Xiaofei, Qian, Yu, Yang, Jian, Ma, Yanchun, Li, Hongyi, Wang, Fang, Liu, Jing, Liu, Xuefeng, Su, Dan, Wang, Yan, Sun, Ruifang, Guo, Shiping, Li, Yaoping, Cheng, Xiaolong, Liu, Zhihua, Zhan, Qimin, Cui, Yongping

“…Esophageal squamous cell carcinoma (ESCC) ranks fourth among cancer-related deaths in China due to the lack of actionable molecules. We performed whole-exome…”
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Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma by Cui, Yongping, Chen, Hongyan, Xi, Ruibin, Cui, Heyang, Zhao, Yahui, Xu, Enwei, Yan, Ting, Lu, Xiaomei, Huang, Furong, Kong, Pengzhou, Li, Yang, Zhu, Xiaolin, Wang, Jiawei, Zhu, Wenjie, Wang, Jie, Ma, Yanchun, Zhou, Yong, Guo, Shiping, Zhang, Ling, Liu, Yiqian, Wang, Bin, Xi, Yanfeng, Sun, Ruifang, Yu, Xiao, Zhai, Yuanfang, Wang, Fang, Yang, Jian, Yang, Bin, Cheng, Caixia, Liu, Jing, Song, Bin, Li, Hongyi, Wang, Yi, Zhang, Yingchun, Cheng, Xiaolong, Zhan, Qimin, Li, Yanhong, Liu, Zhihua

“…Esophageal squamous cell carcinoma (ESCC) is a poor-prognosis cancer type with limited understanding of its molecular etiology. Using 508 ESCC genomes, we…”
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A microRNA-based liquid biopsy signature for the early detection of esophageal squamous cell carcinoma: a retrospective, prospective and multicenter study by Miyoshi, Jinsei, Zhu, Zhongxu, Luo, Aiping, Toden, Shusuke, Zhou, Xuantong, Izumi, Daisuke, Kanda, Mitsuro, Takayama, Tetsuji, Parker, Iqbal M, Wang, Minjie, Gao, Feng, Zaidi, Ali H, Baba, Hideo, Kodera, Yasuhiro, Cui, Yongping, Wang, Xin, Liu, Zhihua, Goel, Ajay

“…Currently, there is no clinically relevant non-invasive biomarker for early detection of esophageal squamous cell carcinoma (ESCC). Herein, we established and…”
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Promoter Methylation-Regulated miR-145-5p Inhibits Laryngeal Squamous Cell Carcinoma Progression by Targeting FSCN1 by Gao, Wei, Zhang, Chunming, Li, Wenqi, Li, Huizheng, Sang, Jiangwei, Zhao, Qinli, Bo, Yunfeng, Luo, Hongjie, Zheng, Xiwang, Lu, Yan, Shi, Yong, Yang, Dongli, Zhang, Ruiping, Li, Zhenyu, Cui, Jiajia, Zhang, Yuliang, Niu, Min, Li, Jun, Wu, Zhongqiang, Guo, Huina, Xiang, Caixia, Wang, Juan, Hou, Juan, Zhang, Lu, Thorne, Rick F., Cui, Yongping, Wu, Yongyan, Wen, Shuxin, Wang, Binquan

“…Laryngeal squamous cell carcinoma (LSCC) is a common form of head and neck cancer with poor prognosis. However, the mechanism underlying the pathogenesis of…”
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Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma by Bi, Yanghui, Guo, Shixing, Xu, Xiaoqin, Kong, Pengzhou, Cui, Heyang, Yan, Ting, Ma, Yanchun, Cheng, Yikun, Chen, Yunqing, Liu, Xue, Zhang, Ling, Cheng, Caixia, Xu, Enwei, Qian, Yu, Yang, Jian, Song, Bin, Li, Hongyi, Wang, Fang, Hu, Xiaoling, Liu, Xiangchen, Niu, Xia, Zhai, Yuanfang, Liu, Jing, Li, Yaoping, Cheng, Xiaolong, Cui, Yongping

“…ZNF750 is one novel significantly mutated gene identified in esophageal squamous cell carcinoma (ESCC) using next-generation sequencing. However, its…”
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CDCA7 promotes TGF‐β‐induced epithelial–mesenchymal transition via transcriptionally regulating Smad4/Smad7 in ESCC by Li, Hongyi, Wang, Shaojie, Li, Xiubo, Weng, Yongjia, Guo, Dinghe, Kong, Pengzhou, Cheng, Caixia, Wang, Yanqiang, Zhang, Ling, Cheng, Xiaolong, Cui, Yongping

“…Cell division cycle associated 7 (CDCA7) is a copy number amplification gene that contributes to the metastasis and invasion of tumors, including esophageal…”
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Phosphoproteomics reveals therapeutic targets of esophageal squamous cell carcinoma by Li, Yi, Yang, Bin, Ma, Yanchun, Peng, Xiaojun, Wang, Zhiyu, Sheng, Bin, Wei, Zichao, Cui, Yongping, Liu, Zhihua

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Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway by Yanchun, Ma, Yi, Wang, Lu, Wang, Yu, Qian, Jian, Yang, Pengzhou, Kong, Ting, Yan, Hongyi, Li, Fang, Wang, Xiaolong, Cheng, Yongping, Cui

“…Triptolide, the component of traditional Chinese herb, has been used as an inflammatory medicine and reported to be anti-tumor for various cancers recently…”
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Loss of KLF14 triggers centrosome amplification and tumorigenesis by Fan, Guangjian, Sun, Lianhui, Shan, Peipei, Zhang, Xianying, Huan, Jinliang, Zhang, Xiaohong, Li, Dali, Wang, Tingting, Wei, Tingting, Zhang, Xiaohong, Gu, Xiaoyang, Yao, Liangfang, Xuan, Yang, Hou, Zhaoyuan, Cui, Yongping, Cao, Liu, Li, Xiaotao, Zhang, Shengping, Wang, Chuangui

“…Centrosome amplification is frequent in cancer, but the underlying mechanisms remain unclear. Here we report that disruption of the Kruppel-like factor 14 (…”
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Regulation of energy homeostasis by the ubiquitin-independent REGγ proteasome by Sun, Lianhui, Fan, Guangjian, Shan, Peipei, Qiu, Xiaoying, Dong, Shuxian, Liao, Lujian, Yu, Chunlei, Wang, Tingting, Gu, Xiaoyang, Li, Qian, Song, Xiaoyu, Cao, Liu, Li, Xiaotao, Cui, Yongping, Zhang, Shengping, Wang, Chuangui

“…Maintenance of energy homeostasis is essential for cell survival. Here, we report that the ATP- and ubiquitin-independent REGγ-proteasome system plays a role…”
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Characterization of somatic structural variations in 528 Chinese individuals with Esophageal squamous cell carcinoma by Cui, Heyang, Zhou, Yong, Wang, Fang, Cheng, Caixia, Zhang, Weimin, Sun, Ruifang, Zhang, Ling, Bi, Yanghui, Guo, Min, Zhou, Yan, Wang, Xinhui, Ren, Jiaxin, Bai, Ruibing, Ding, Ning, Cheng, Chen, Wang, Longlong, Zhuang, Xuehan, Gao, Mingwei, Weng, Yongjia, Wu, Yueguang, Liu, Huijuan, Li, Shuaicheng, Wang, Shubin, Cheng, Xiaolong, Cui, Yongping, Liu, Zhihua, Zhan, Qimin

“…Esophageal squamous cell carcinoma (ESCC) demonstrates high genome instability. Here, we analyze 528 whole genomes to investigate structural variations’…”
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Author Correction: Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma by Yan, Ting, Cui, Heyang, Zhou, Yong, Yang, Bin, Kong, Pengzhou, Zhang, Yingchun, Liu, Yiqian, Wang, Bin, Cheng, Yikun, Li, Jiayi, Guo, Shixing, Xu, Enwei, Liu, Huijuan, Cheng, Caixia, Zhang, Ling, Chen, Ling, Zhuang, Xiaofei, Qian, Yu, Yang, Jian, Ma, Yanchun, Li, Hongyi, Wang, Fang, Liu, Jing, Liu, Xuefeng, Su, Dan, Wang, Yan, Sun, Ruifang, Guo, Shiping, Li, Yaoping, Cheng, Xiaolong, Liu, Zhihua, Zhan, Qimin, Cui, Yongping

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Leveraging new methods for comprehensive characterization of mitochondrial DNA in esophageal squamous cell carcinoma by Zhuang, Xuehan, Ye, Rui, Zhou, Yong, Cheng, Matthew Yibo, Cui, Heyang, Wang, Longlong, Zhang, Shuangping, Wang, Shubin, Cui, Yongping, Zhang, Weimin

“…Mitochondria play essential roles in tumorigenesis; however, little is known about the contribution of mitochondrial DNA (mtDNA) to esophageal squamous cell…”
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Autophagy-Related Three-Gene Prognostic Signature for Predicting Survival in Esophageal Squamous Cell Carcinoma by Cui, Heyang, Weng, Yongjia, Ding, Ning, Cheng, Chen, Wang, Longlong, Zhou, Yong, Zhang, Ling, Cui, Yongping, Zhang, Weimin

“…Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive malignant tumors in China, and its prognosis remains poor. Autophagy is an…”
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Deep proteome profiling promotes whole proteome characterization and drug discovery for esophageal squamous cell carcinoma by Liu, Wei, Cui, Yongping, Liu, Wen, Liu, Zhihua, Xu, Liyan, Li, Enmin

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An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma by Gao, Yingzhen, Shen, Liuyi, Dong, Tianyue, Yang, Xin, Cui, Heyang, Guo, Yanlin, Ma, Yanchun, Kong, Pengzhou, Cheng, Xiaolong, Zhang, Ling, Cui, Yongping

“…Abstract Background Aberrant glycosylation has been recognized as a hallmark of cancer and N-glycosylation is one of the main types of glycosylation in…”
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Roles of Kruppel-associated Box (KRAB)-associated Co-repressor KAP1 Ser-473 Phosphorylation in DNA Damage Response by Hu, Chen, Zhang, Shengping, Gao, Xuan, Gao, Xiaojing, Xu, Xiaohong, Lv, Ya, Zhang, Yan, Zhu, Zhenhong, Zhang, Changqing, Li, Qiao, Wong, Jiemin, Cui, Yongping, Zhang, Wen, Ma, Lin, Wang, Chuangui

“…The Kruppel-associated box (KRAB)-associated co-repressor KAP1 is an essential nuclear co-repressor for the KRAB zinc finger protein superfamily of…”
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Author Correction: Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma by Cui, Yongping, Chen, Hongyan, Xi, Ruibin, Cui, Heyang, Zhao, Yahui, Xu, Enwei, Yan, Ting, Lu, Xiaomei, Huang, Furong, Kong, Pengzhou, Li, Yang, Zhu, Xiaolin, Wang, Jiawei, Zhu, Wenjie, Wang, Jie, Ma, Yanchun, Zhou, Yong, Guo, Shiping, Zhang, Ling, Liu, Yiqian, Wang, Bin, Xi, Yanfeng, Sun, Ruifang, Yu, Xiao, Zhai, Yuanfang, Wang, Fang, Yang, Jian, Yang, Bin, Cheng, Caixia, Liu, Jing, Song, Bin, Li, Hongyi, Wang, Yi, Zhang, Yingchun, Cheng, Xiaolong, Zhan, Qimin, Li, Yanhong, Liu, Zhihua

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Integrative Genomic Analyses of 1,145 Patient Samples Reveal New Biomarkers in Esophageal Squamous Cell Carcinoma by Zou, Binbin, Guo, Dinghe, Kong, Pengzhou, Wang, Yanqiang, Cheng, Xiaolong, Cui, Yongping

“…Due to the lack of effective diagnostic markers and therapeutic targets, esophageal squamous cell carcinoma (ESCC) shows a poor 5 years survival rate of less…”
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