Search Results - "YONEDA, Ken Y"

Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells by Alizadeh, Javad, Zeki, Amir A., Mirzaei, Nima, Tewary, Sandipan, Rezaei Moghadam, Adel, Glogowska, Aleksandra, Nagakannan, Pandian, Eftekharpour, Eftekhar, Wiechec, Emilia, Gordon, Joseph W., Xu, Fred. Y., Field, Jared T., Yoneda, Ken Y., Kenyon, Nicholas J., Hashemi, Mohammad, Hatch, Grant M., Hombach-Klonisch, Sabine, Klonisch, Thomas, Ghavami, Saeid

“…The mevalonate (MEV) cascade is responsible for cholesterol biosynthesis and the formation of the intermediate metabolites geranylgeranylpyrophosphate (GGPP)…”
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Safety and Feasibility of a Novel Externally Cooled Bronchoscopic Radiofrequency Ablation Catheter for Ablation of Peripheral Lung Tumours: A First-In-Human Dose Escalation Study by Steinfort, Daniel P, Antippa, Phillip, Rangamuwa, Kanishka, Irving, Louis B, Christie, Michael, Chan, Ewan, Marinelli, Brett, Wang, Jie, Yoneda, Ken Y, Raina, Shashank, Herth, Felix J

“…Radiofrequency ablation (RFA) is an established modality for percutaneous ablation of non-small cell lung cancer (NSCLC) in medically inoperable patients but…”
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Investigation of metabolomic blood biomarkers for detection of adenocarcinoma lung cancer by Fahrmann, Johannes F, Kim, Kyoungmi, DeFelice, Brian C, Taylor, Sandra L, Gandara, David R, Yoneda, Ken Y, Cooke, David T, Fiehn, Oliver, Kelly, Karen, Miyamoto, Suzanne

“…Untargeted metabolomics was used in case-control studies of adenocarcinoma (ADC) lung cancer to develop and test metabolite classifiers in serum and plasma as…”
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High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer by Xiao, Wenwu, Ma, Weijie, Wei, Sixi, Li, Qianping, Liu, Ruiwu, Carney, Randy P, Yang, Kevin, Lee, Joyce, Nyugen, Alan, Yoneda, Ken Y, Lam, Kit S, Li, Tianhong

“…α3β1 integrin is a promising cancer biomarker and drug target. We previously identified a 9-amino-acid cyclic peptide LXY30 for detecting α3β1 integrin on the…”
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The asthma-chronic obstructive pulmonary disease overlap syndrome: pharmacotherapeutic considerations by Louie, Samuel, Zeki, Amir A, Schivo, Michael, Chan, Andrew L, Yoneda, Ken Y, Avdalovic, Mark, Morrissey, Brian M, Albertson, Timothy E

“…Asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) is a commonly encountered yet loosely defined clinical entity. ACOS accounts for…”
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Interventional pulmonology use of cell-free DNA assay for metastatic non–small cell lung cancer: the UC Davis experience by Phan, Chinh, Jespersen, Forrest, Weipert, Caroline, Li, Tianhong, Yoneda, Ken Y.

“…Background: Interventional pulmonologists (IPs) are often the first specialist to see patients with suspected metastatic non–small cell lung cancer (mNSCLC)…”
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Severe nivolumab-induced pneumonitis preceding durable clinical remission in a patient with refractory, metastatic lung squamous cell cancer: a case report by Li, Hong, Ma, Weijie, Yoneda, Ken Y, Moore, Elizabeth H, Zhang, Yanhong, Pu, Lee L Q, Frampton, Garrett M, Molmen, Michael, Stephens, Philip J, Li, Tianhong

“…Programmed cell death 1 (PD-1) and its ligand 1 (PD-L1) inhibitors have quickly become standard of care for patients with advanced non-small cell lung cancer…”
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Systemic Metabolomic Changes in Blood Samples of Lung Cancer Patients Identified by Gas Chromatography Time-of-Flight Mass Spectrometry by Miyamoto, Suzanne, Taylor, Sandra L, Barupal, Dinesh K, Taguchi, Ayumu, Wohlgemuth, Gert, Wikoff, William R, Yoneda, Ken Y, Gandara, David R, Hanash, Samir M, Kim, Kyoungmi, Fiehn, Oliver

“…Lung cancer is a leading cause of cancer deaths worldwide. Metabolic alterations in tumor cells coupled with systemic indicators of the host response to tumor…”
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Small molecule tyrosine kinase inhibitors modulated blood immune cell counts in patients with oncogene-driven NSCLC by Ma, Weijie, Zeng, Jie, Chen, Shuai, Lyu, Yue, Toomey, Kyra A, Phan, Chinh T, Yoneda, Ken Y, Li, Tianhong

“…Lack of biomarkers and in vitro models has contributed to inadequate understanding of the mechanisms underlying the inferior clinical response to immune…”
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Correction to: High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer by Xiao, Wenwu, Ma, Weijie, Wei, Sixi, Li, Qianping, Liu, Ruiwu, Carney, Randy P, Yang, Kevin, Lee, Joyce, Nyugen, Alan, Yoneda, Ken Y, Lam, Kit S, Li, Tianhong

“…The original article [1] contains an error in Fig. 2 whereby Fig. 2D has mistakenly been omitted. Fig. 2 can be viewed in its entirety - including Fig. 2D - in…”
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Airway transcriptomic profiling after bronchial thermoplasty by Liao, Shu-Yi, Linderholm, Angela L, Yoneda, Ken Y, Kenyon, Nicholas J, Harper, Richart W

“…Bronchial thermoplasty is a nonpharmacological, device-based treatment option for a specific population of severe asthmatic subjects, but the underlying…”
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Molecular testing strategies in non-small cell lung cancer: optimizing the diagnostic journey by Gregg, Jeffrey P., Li, Tianhong, Yoneda, Ken Y.

“…Molecular testing identifies patients with advanced non-small cell lung cancer (NSCLC) who may benefit from targeted therapy or immunotherapy (i.e., immune…”
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Simvastatin Overcomes Resistance to Tyrosine Kinase Inhibitors in Patient-derived, Oncogene-driven Lung Adenocarcinoma Models by Ma, Weijie, Wei, Sixi, Li, Qianping, Zeng, Jie, Xiao, Wenwu, Zhou, Chihong, Yoneda, Ken Y, Zeki, Amir A, Li, Tianhong

“…There is an unmet clinical need to develop novel strategies to overcome resistance to tyrosine kinase inhibitors (TKI) in patients with oncogene-driven lung…”
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Peritoneal and pleural ports for management of refractory ascites and pleural effusions: assessment of impact on patient quality of life and hospice/home nursing care by Monsky, Wayne L, Yoneda, Ken Y, MacMillan, John, Deutsch, Larry-Stuart, Dong, Paul, Hourigan, Helen, Schwartz, Yvonne, Magee, Stacey, Duffield, Curtis, Boak, Tammy, Cernilia, James

“…Patients with end-stage malignancies often have refractory ascites or pleural effusions requiring repeated paracenteses or thoracenteses. Subcutaneous…”
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Bronchial Thermoplasty: A New Treatment Paradigm for Severe Persistent Asthma by Cayetano, Katherine S., Chan, Andrew L., Albertson, Timothy E., Yoneda, Ken Y.

“…Patients with severe asthma represent only a minority of the total asthma population; however, they account for the majority of the mortality, morbidity, and…”
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Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial by Rahman, Najib M, Pepperell, Justin, Rehal, Sunita, Saba, Tarek, Tang, Augustine, Ali, Nabeel, West, Alex, Hettiarachchi, Gihan, Mukherjee, Dipak, Samuel, Johnson, Bentley, Andrew, Dowson, Lee, Miles, Jonathan, Ryan, C. Frank, Yoneda, Ken Y, Chauhan, Anoop, Corcoran, John P, Psallidas, Ioannis, Wrightson, John M, Hallifax, Rob, Davies, Helen E, Lee, Y. C. Gary, Dobson, Melissa, Hedley, Emma L, Seaton, Douglas, Russell, Nicky, Chapman, Margaret, McFadyen, Bethan M, Shaw, Rachel A, Davies, Robert J. O, Maskell, Nick A, Nunn, Andrew J, Miller, Robert F

“…IMPORTANCE: For treatment of malignant pleural effusion, nonsteroidal anti-inflammatory drugs (NSAIDs) are avoided because they may reduce pleurodesis…”
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Endobronchial Phenylephrine in Airway Bleeding During Bronchoscopy Does not Cause Hypertension: A Retrospective Observational Study by Kim, Jeremy, Phan, Chinh, Adams, Jason, Cortes-Puch, Irene, Stocking, Jacqueline C, Liu, Anna, Ren, Yunyi, Taylor, Sandra, Yoneda, Ken Y

“…Bleeding is a known complication during bronchoscopy, with increased incidence in patients undergoing a more invasive procedure. Phenylephrine is a potent…”
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Interstitial Lung Disease Associated with Crizotinib in Patients with Advanced Non-Small-Cell Lung Cancer: Independent Review of Four PROFILE Trials by Yoneda, Ken Y, Scranton, Judith R, Cadogan, Michael A, Tassell, Vanessa, Nadanaciva, Sashi, Wilner, Keith D, Stollenwerk, Nicholas S

“…Abstract Introduction Interstitial lung disease (ILD) is a rare, potentially serious side effect associated with crizotinib, a tyrosine kinase inhibitor for…”
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Bronchial Thermoplasty: A Decade of Experience: State of the Art by Tan, Laren D., Yoneda, Ken Y., Louie, Samuel, Hogarth, D. Kyle, Castro, Mario

“…Bronchial thermoplasty (BT) delivers targeted radiofrequency energy to bronchial airway walls and results in the partial ablation of the airway smooth muscle…”
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Safety and Clinical Utility of Flexible Bronchoscopic Cryoextraction in Patients With Non-neoplasm Tracheobronchial Obstruction: A Retrospective Chart Review by Sriratanaviriyakul, Narin, Lam, Francis, Morrissey, Brian M, Stollenwerk, Nicholas, Schivo, Michael, Yoneda, Ken Y

“…Airway obstruction from blood clots, airway secretions, and foreign bodies is a potentially life-threatening condition. Optimal management of this problem,…”
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