Search Results - "YONEDA, FUMIO"

Synergistic effects of selegiline and donepezil on cognitive impairment induced by amyloid beta (25–35) by Tsunekawa, Hiroko, Noda, Yukihiro, Mouri, Akihiro, Yoneda, Fumio, Nabeshima, Toshitaka

“…Selegiline, an irreversible inhibitor of monoamine oxidase B used in the treatment of Parkinson's disease, has been demonstrated to have a potential…”
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The Facile Synthesis of 6-Azapurines by Transformation of Toxoflavins (7-Azapteridines) by Nagamatsu, Tomohisa, Ma, Jun, Yoneda, Fumio

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Retinal Neuronal Death Induced by Intraocular Administration of a Nitric Oxide Donor and Its Rescue by Neurotrophic Factors in Rats by Takahata, Kazue, Katsuki, Hiroshi, Kume, Toshiaki, Nakata, Daisuke, Ito, Ken, Muraoka, Shizuko, Yoneda, Fumio, Kashii, Satoshi, Honda, Yoshihito, Akaike, Akinori

“…To investigate the neurotoxic outcome in the rat retina exposed to nitric oxide (NO) released from an NO donor and to evaluate the effects of neurotrophic…”
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Effects of ( R)-(−)-1-(benzofuran-2-yl)-2-propylaminopentane hydrochloride [(−)-BPAP] in animal models of mood disorders by Tsunekawa, Hiroko, Noda, Yukihiro, Miyazaki, Masayuki, Yoneda, Fumio, Nabeshima, Toshitaka, Wang, Dayong

“…( R)-(−)-1-(Benzofuran-2-yl)-2-propylaminopentane hydrochloride [(−)-BPAP] is a highly potent enhancer of impulse propagation-mediated monoamine release and an…”
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Neuroprotective function of R-(−)-1-(benzofuran-2-yl)-2-propylaminopentane, [ R-(−)-BPAP], against apoptosis induced by N-methyl( R)salsolinol, an endogenous dopaminergic neurotoxin, in human dopaminergic neuroblastoma SH-SY5Y cells by Maruyama, Wakako, Yi, Hong, Takahashi, Tsutomu, Shimazu, Seiichiro, Ohde, Hironori, Yoneda, Fumio, Iwasa, Kinuko, Naoi, Makoto

“…R-(−)-1-(Benzofuran-2-yl)-2-propylaminopentane HCl [ R-(−)-BPAP] is one of “catecholaminergic and serotonergic enhancers“, which were proposed to improve…”
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Antidiabetic and adipogenic properties in a newly synthesized thiazolidine derivative, FPFS-410 by Norisada, Nobuyoshi, Masuzaki, Hiroaki, Fujimoto, Muneya, Inoue, Gen, Hosoda, Kiminori, Hayashi, Tatsuya, Watanabe, Mayumi, Muraoka, Shizuko, Yoneda, Fumio, Nakao, Kazuwa

“…We report here a newly synthesized cyanoimino-oxothiazolidine derivative, FPFS-410, which has properties to ameliorate both hyperglycemia and dyslipidemia…”
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(−)1‐(Benzofuran‐2‐yl)‐2‐propylaminopentane, [(−)BPAP], a selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain by Knoll, Joseph, Yoneda, Fumio, Knoll, Berta, Ohde, Hironori, Miklya, Ildikó

“…The brain constituents β‐phenylethylamine (PEA) and tryptamine enhance the impulse propagation mediated transmitter release (exocytosis) from the…”
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Enhancer substances: Selegiline and R-(–)-1-(benzofuran-2-yl)-2-propylaminopentane [(–)-BPAP] enhance the neurotrophic factor synthesis on cultured mouse astrocytes by Shimazu, Seiichiro, Tanigawa, Akie, Sato, Noriyuki, Yoneda, Fumio, Hayashi, Kyozo, Knoll, Joseph

“…R-(–)-1-(Benzofuran-2-yl)-2-propylaminopentane [(–)-BPAP] is a potent “catecholaminergic and serotonergic activity enhancer (CAE/SAE)”, which enhances the…”
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Effects of R-(−)-BPAP on the Expressions of Neurotrophins and Their Receptors in Mesencephalic Slices by Hirami, Chieko, Takahata, Kazue, Shimazu, Seiichiro, Yoneda, Fumio, Hayashi, Kyozo, Katsuki, Hiroshi, Akaike, Akinori

“…R-(−)-1-(Benzofuran-2-yl)-2-propylaminopentane [R-(−)-BPAP] enhances electric field stimulation-induced release of catecholamine from isolated brain stem and…”
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Retinal Neurotoxicity of Nitric Oxide Donors With Different Half-Life of Nitric Oxide Release: Involvement of N-Methyl- D -aspartate Receptor by Takahata, Kazue, Katsuki, Hiroshi, Kume, Toshiaki, Ito, Ken, Tochikawa, Yoshinaga, Muraoka, Shizuko, Yoneda, Fumio, Kashii, Satoshi, Honda, Yoshihito, Akaike, Akinori

“…We compared the degree of neurotoxic outcome in the retina exposed to three nitric oxide (NO) donors with different half-life of NO release. Intravitreal…”
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The novel catecholaminergic and serotoninergic activity enhancer R-(−)-1-(benzofuran-2-yl)-2-propylaminopentane up-regulates neurotrophic factor synthesis in mouse astrocytes by Ohta, Kiyoe, Ohta, Mitsuhiro, Mizuta, Ikuko, Fujinami, Aya, Shimazu, Seiichiro, Sato, Noriyuki, Yoneda, Fumio, Hayashi, Kyozo, Kuno, Sadako

“…We investigated the effects of the novel catecholaminergic and serotoninergic activity enhancer R-(−)-1-(benzofuran-2-yl)-2-propylaminopentane ((−)-BPAP) on…”
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Geroprotection in the future. In memoriam of Joseph Knoll: The selegiline story continues by Ferdinandy, Peter, Yoneda, Fumio, Muraoka, Shizuko, Fürst, Susanna, Gyires, Klara, Miklya, Ildiko

“…In memoriam of Joseph Knoll: the selegiline story continues…”
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Theoretical study on the lowest-frequency mode of the flavin ring by Nakai, Sachiko, Yoneda, Fumio, Yamabe, Tokio

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DNA Oligomers Having a Diazapyrenium Dication (DAP2+); Synthesis and DNA Cleavage Activities by IKEDA, Hisafumi, FUJI, Kaoru, TANAKA, Kiyoshi, ISO, Yasuyoshi, YONEDA, Fumio

“…Aiming at the creation of functionalized antisense DNA oligomers possessing site-selective DNA cleaving activity, viologen and a related compound,…”
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Effects of R-(-)-BPAP on the Expressions of Neurotrophins and Their Receptors in Mesencephalic Slices by Chieko HIRAMIa, Kazue TAKAHATAa, Seiichiro SHIMAZUa, Fumio YONEDAa, Kyozo HAYASHIb, Hiroshi KATSUKIc, Akinori AKAIKEc

“…R-(-)-1-(Benzofuran-2-yl)-2-propylaminopentane [R-(-)-BPAP] enhances electric field stimulation-induced release of catecholamine from isolated brain stem and…”
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Synthesis and evaluation of nitro 5-deazaflavins as novel bioreductive antitumor agents by Kawamoto, Tetsuji, Ikeuchi, Yoshihiro, Hiraki, Junko, Eikyu, Yoshiteru, Shimizu, Kazue, Tomishima, Masaki, Bessho, Kiyoshi, Yoneda, Fumio, Mikata, Yuji, Nishida, Mamiko, Ikehara, Kenji, Sasaki, Takuma

“…A series of nitro 5-deazaflavins, 5-deazaflavins possessing a nitro group at C(6)–C(9) position, has been designed and synthesized as a novel class of…”
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Simple New Method for the Synthesis of 5-Deaza-10-oxaflavin, a Potential Organic Oxidant by CHEN, Xing, TANAKA, Kiyoshi, YONEDA, Fumio

“…Several 5-deaza-10-oxaflavin (2H-chromeno[2, 3-d]pyrimidine-2, 4(3H)dione) derivatives (1) were prepared in satisfactory yields through new, practical routes…”
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Antitumor studies. Part 1: Design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents by Ali, Hamed I., Tomita, Keiichiro, Akaho, Eiichi, Kambara, Hiroto, Miura, Shinji, Hayakawa, Hiroyuki, Ashida, Noriyuki, Kawashima, Yutaka, Yamagishi, Takehiro, Ikeya, Hisao, Yoneda, Fumio, Nagamatsu, Tomohisa

“…The prepared 2-deoxo-2-phenyl-5-deazaflavins ( 1) and 2-deoxo-2-phenylflavin-5-oxides ( 2) exhibited significant antitumor activities against CCRF-HSB-2, KB,…”
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Antidepressant-like effects of selegiline in the forced swim test by Shimazu, Seiichiro, Minami, Akiko, Kusumoto, Haruko, Yoneda, Fumio

“…Although selegiline, a monoamine oxidase (MAO)-B inhibitor, is reported to exert antidepressant effects in depressant patients, evidence in rodents for effects…”
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Effects of selegiline alone or with donepezil on memory impairment in rats by Takahata, Kazue, Minami, Akiko, Kusumoto, Haruko, Shimazu, Seiichiro, Yoneda, Fumio

“…Selegiline, a monoamine oxidase-B inhibitor, is reported to improve memory and learning in dementia of Alzheimer's type. However, only a few studies have…”
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