Search Results - "YOLKEN, R. H"
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Are some cases of psychosis caused by microbial agents? A review of the evidence
Published in Molecular psychiatry (01-05-2008)“…The infectious theory of psychosis, prominent early in the twentieth century, has recently received renewed scientific support. Evidence has accumulated that…”
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2
The complement system: a gateway to gene–environment interactions in schizophrenia pathogenesis
Published in Molecular psychiatry (01-11-2017)“…The pathogenesis of schizophrenia is considered to be multi-factorial, with likely gene–environment interactions (GEI). Genetic and environmental risk factors…”
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Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress
Published in Molecular psychiatry (01-07-2004)“…The etiology and pathophysiology of schizophrenia remain unknown. A parallel transcriptomics, proteomics and metabolomics approach was employed on human brain…”
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4
Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci
Published in Molecular psychiatry (01-03-2014)“…Genetic and environmental components as well as their interaction contribute to the risk of schizophrenia, making it highly relevant to include environmental…”
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Toxoplasma and schizophrenia
Published in Parasite immunology (01-11-2009)“…Summary Research on infectious agents as a possible cause of schizophrenia has become prominent in the past decade. Toxoplasma gondii has emerged as a prime…”
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Identification of a biological signature for schizophrenia in serum
Published in Molecular psychiatry (01-05-2012)“…Biomarkers are now used in many areas of medicine but are still lacking for psychiatric conditions such as schizophrenia (SCZ). We have used a multiplex…”
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MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway
Published in Neuroscience (30-05-2014)“…Highlights • We examine changes of over 1000 miRNAs in human neural cells by Toxoplasma infection. • MiR-132 is highly upregulated by all three prototype…”
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Development of a blood-based molecular biomarker test for identification of schizophrenia before disease onset
Published in Translational psychiatry (14-07-2015)“…Recent research efforts have progressively shifted towards preventative psychiatry and prognostic identification of individuals before disease onset. We…”
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Sex-specific changes in gene expression and behavior induced by chronic Toxoplasma infection in mice
Published in Neuroscience (29-03-2012)“…Abstract There is growing evidence that Toxoplasma gondii modifies the behavior of its intermediate hosts. We investigated the molecular basis of these…”
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Maternal mid-pregnancy C-reactive protein and risk of autism spectrum disorders: the early markers for autism study
Published in Translational psychiatry (19-04-2016)“…Maternal pregnancy levels of the inflammatory marker C-reactive protein (CRP) has been previously associated with autism spectrum disorder (ASD) in the…”
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Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia
Published in Molecular psychiatry (01-01-2013)Get full text
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Cytomegalovirus infection associated with smaller cerebellum in severe mental illness
Published in EUROPEAN PSYCHIATRY (01-03-2023)“…Introduction Postnatal cytomegalovirus (CMV) infection of immunocompetent hosts is usually inapparent but typically results in lifelong latency. Congenital CMV…”
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Journal Article Conference Proceeding -
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Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress
Published in Molecular psychiatry (01-07-2004)“…The etiology and pathophysiology of schizophrenia remain unknown. A parallel transcriptomics, proteomics and metabolomics approach was employed on human brain…”
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Journal Article -
14
Persistent infection with neurotropic herpes viruses and cognitive impairment
Published in Psychological medicine (01-05-2013)“…Herpes virus infections can cause cognitive impairment during and after acute encephalitis. Although chronic, latent/persistent infection is considered to be…”
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Journal Article -
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Cytomegalovirus seropositivity and serointensity are associated with hippocampal volume and verbal memory in schizophrenia and bipolar disorder
Published in Progress in neuro-psychopharmacology & biological psychiatry (03-01-2014)“…Cytomegalovirus (CMV) is a member of the herpesviridae family that has a limbic and temporal gray matter tropism. It is usually latent in humans but has been…”
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Cytomegalovirus Antibody Elevation in Bipolar Disorder: Relation to Elevated Mood States
Published in Neural plasticity (01-01-2015)“…The neurobiology of mood states is complicated by exposure to everyday stressors (e.g., psychosocial, ubiquitous environmental infections like CMV), each…”
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Strain hypothesis of Toxoplasma gondii infection on the outcome of human diseases
Published in Acta Physiologica (01-04-2015)“…The intracellular protozoan Toxoplasma gondii is an exceptionally successful food and waterborne parasite that infects approximately 1 billion people…”
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The Stanley Foundation brain collection and Neuropathology Consortium
Published in Schizophrenia research (03-08-2000)“…The Stanley Foundation brain collection is an attempt to supplement existing brain collections for the purpose of promoting research on schizophrenia and…”
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Brain morphological changes associated with exposure to HSV1 in first-episode schizophrenia
Published in Molecular psychiatry (01-01-2007)“…Infectious agents have been proposed as one of the risk factors for schizophrenia. However, the data on the association of infectious agents with in vivo brain…”
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Influence of maternal infections on neonatal acute phase proteins and their interaction in the development of non-affective psychosis
Published in Translational psychiatry (03-02-2015)“…Although primary infections with Toxoplasma gondii or herpes viruses during pregnancy are established teratogens, chronic maternal infections with these…”
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