Search Results - "YOICHI, Maekawa"

Practical methods for collecting Trichinella parasites and their excretory-secretory products by Wu, Zhiliang, Nagano, Isao, Takahashi, Yuzo, Maekawa, Yoichi

“…Abstract Trichinella is a unique nematode. Its developmental stages include adult worms, newborn larvae, and muscle larvae. Besides humans, the parasite also…”
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How does spaceflight affect the acquired immune system? by Akiyama, Taishin, Horie, Kenta, Hinoi, Eiichi, Hiraiwa, Manami, Kato, Akihisa, Maekawa, Yoichi, Takahashi, Akihisa, Furukawa, Satoshi

“…The impact of spaceflight on the immune system has been investigated extensively during spaceflight missions and in model experiments conducted on Earth. Data…”
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A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans by Kitamura, Akiko, Maekawa, Yoichi, Uehara, Hisanori, Izumi, Keisuke, Kawachi, Izumi, Nishizawa, Masatoyo, Toyoshima, Yasuko, Takahashi, Hitoshi, Standley, Daron M, Tanaka, Keiji, Hamazaki, Jun, Murata, Shigeo, Obara, Koji, Toyoshima, Itaru, Yasutomo, Koji

“…Proteasomes are multisubunit proteases that play a critical role in maintaining cellular function through the selective degradation of ubiquitinated proteins…”
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Neutrophil Elastase Damages the Pulmonary Endothelial Glycocalyx in Lipopolysaccharide-Induced Experimental Endotoxemia by Suzuki, Kodai, Okada, Hideshi, Takemura, Genzou, Takada, Chihiro, Kuroda, Ayumi, Yano, Hirohisa, Zaikokuji, Ryogen, Morishita, Kentaro, Tomita, Hiroyuki, Oda, Kazumasa, Matsuo, Saori, Uchida, Akihiro, Fukuta, Tetsuya, Sampei, So, Miyazaki, Nagisa, Kawaguchi, Tomonori, Watanabe, Takatomo, Yoshida, Takahiro, Ushikoshi, Hiroaki, Yoshida, Shozo, Maekawa, Yoichi, Ogura, Shinji

“…Neutrophil elastase (NE) is necessary for effective sterilization of phagocytosed bacterial and fungal pathogens; however, NE increases alveolocapillary…”
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Notch signaling drives IL-22 secretion in CD4⁺ T cells by stimulating the aryl hydrocarbon receptor by Alam, Muhammad Shamsul, Maekawa, Yoichi, Kitamura, Akiko, Tanigaki, Kenji, Yoshimoto, Takayuki, Kishihara, Kenji, Yasutomo, Koji

“…CD4⁺ helper T (Th) cells differentiate toward distinct effector cell lineages characterized by their distinct cytokine expression patterns and functions…”
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The neuroprotective effects of FG-4592, a hypoxia-inducible factor-prolyl hydroxylase inhibitor, against oxidative stress induced by alpha-synuclein in N2a cells by Fujimaki, Ayaka, Ohuchi, Kazuki, Takizawa, Shinnosuke, Murakami, Takanori, Kurita, Hisaka, Hozumi, Isao, Wen, Xiaopeng, Kitamura, Yoshihisa, Wu, Zhiliang, Maekawa, Yoichi, Inden, Masatoshi

“…Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra. The pathological hallmark…”
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Trichinella pseudospiralis-secreted 53 kDa protein ameliorates imiquimod-induced psoriasis by inhibiting the IL-23/IL-17 axis in mice by Khueangchiangkhwang, Sukhonthip, Wu, Zhiliang, Nagano, Isao, Maekawa, Yoichi

“…Trichinella infection can experimentally ameliorate many autoimmune diseases. However, the immune mechanism of the amelioration and the identification of…”
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A New Species of Lagochondria (Crustacea: Copepoda) Parasitic on Callionymid Fish: First Record of Precopulatory Mate Guarding in Fish-Parasitic Cyclopoid Copepods, and of the Occurrence of the Genus in the North Pacific by Ohtsuka, Susumu, Nitta, Masato, Nakamura, Toru, Maekawa, Yoichi

“…A new species of the genus of the parasitic cyclopoid family Chondracanthidae is described from the gill cavity of the callionymid (Jordan and Fowler, 1903)…”
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Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis‐associated cholangiocarcinoma by Wu, Zhiliang, Boonmars, Thidarut, Nagano, Isao, Boonjaraspinyo, Sirintip, Srinontong, Piyarat, Ratasuwan, Panaratana, Narong, Khuntikeo, Nielsen, Phuangphaka Sadee, Maekawa, Yoichi

“…Cholangiocarcinoma (CCA) is a malignancy of bile duct with the difficulty in early diagnosis, poor prognosis and less alternation in therapy. S100P is a member…”
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Neutrophil Elastase Inhibition Ameliorates Endotoxin-induced Myocardial Injury Accompanying Degradation of Cardiac Capillary Glycocalyx by Fukuta, Tetsuya, Okada, Hideshi, Takemura, Genzou, Suzuki, Kodai, Takada, Chihiro, Tomita, Hiroyuki, Suzuki, Akio, Oda, Kazumasa, Uchida, Akihiro, Matsuo, Saori, Fukuda, Hirotsugu, Yano, Hirohisa, Muraki, Isamu, Zaikokuji, Ryogen, Kuroda, Ayumi, Nishio, Ayane, Sampei, So, Miyazaki, Nagisa, Hotta, Yasuaki, Yamada, Noriaki, Watanabe, Takatomo, Morishita, Kentaro, Doi, Tomoaki, Yoshida, Takahiro, Ushikoshi, Hiroaki, Yoshida, Shozo, Maekawa, Yoichi, Ogura, Shinji

“…ABSTRACTMyocardial injury in sepsis may be caused by a burst of several inflammatory mediators, leading to vascular endothelial injuries. However, the…”
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Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ+CD8αα+ T cells by Ishifune, Chieko, Tsukumo, Shin-Ichi, Maekawa, Yoichi, Hozumi, Katsuto, Chung, Doo Hyun, Motozono, Chihiro, Yamasaki, Sho, Nakano, Hiroyasu, Yasutomo, Koji

“…Intestinal intraepithelial lymphocytes (IELs) expressing CD8αα on αβ T cells (TCRαβ+CD8αα+ IELs) have suppressive capabilities in enterocolitis, but the…”
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Notch2 signaling is required for potent antitumor immunity in vivo by Sugimoto, Koji, Maekawa, Yoichi, Kitamura, Akiko, Nishida, Jun, Koyanagi, Akemi, Yagita, Hideo, Kojima, Hidefumi, Chiba, Shigeru, Shimada, Mitsuo, Yasutomo, Koji

“…CD8(+) T cells play a central role in cancer immunosurveillance, and the efficient induction of CTLs against tumor Ags is required for successful immunotherapy…”
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The circulating immunoglobulins negatively impact on the parasite clearance in the liver of Leishmania donovani-infected mice via dampening ROS activity by Srinontong, Piyarat, Wu, Zhiliang, Sato, Katsuya, Nagaoka, Hitoshi, Maekawa, Yoichi

“…Visceral leishmaniasis, the most severe form of leishmaniasis, is caused by Leishmania donovani and L. infantum. Immunity to Leishmania infection has been…”
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Abrogation of Rbpj attenuates experimental autoimmune uveoretinitis by inhibiting IL-22-producing CD4+ T cells by Bhuyan, Zaied Ahmed, Asanoma, Michihito, Iwata, Akiko, Ishifune, Chieko, Maekawa, Yoichi, Shimada, Mitsuo, Yasutomo, Koji

“…Experimental autoimmune uveoretinitis (EAU) is an organ-specific T cell-mediated disease induced by immunizing mice with interphotoreceptor retinoid binding…”
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CD98 Heavy Chain Is a Potent Positive Regulator of CD4+ T Cell Proliferation and Interferon-γ Production In Vivo by Kurihara, Takeshi, Arimochi, Hideki, Bhuyan, Zaied Ahmed, Ishifune, Chieko, Tsumura, Hideki, Ito, Morihiro, Ito, Yasuhiko, Kitamura, Akiko, Maekawa, Yoichi, Yasutomo, Koji

“…Upon their recognition of antigens presented by the MHC, T cell proliferation is vital for clonal expansion and the acquisition of effector functions, which…”
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Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model by Nishide, Shunji, Matsunaga, Shinji, Shiota, Masayuki, Yamaguchi, Takehiro, Kitajima, Shojiro, Maekawa, Yoichi, Takeda, Norihiko, Tomura, Michio, Uchida, Junji, Miura, Katsuyuki, Nakatani, Tatsuya, Tomita, Shuhei

“…The tumor microenvironment (TME) polarizes tumor-infiltrating macrophages toward tumor support. Macrophage-abundant tumors are highly malignant and are the…”
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The Lifestyle of the Segmented Filamentous Bacterium: A Non-Culturable Gut-Associated Immunostimulating Microbe Inferred by Whole-Genome Sequencing by TOMOMI, Kuwahara, YOSITOSHI, Ogura, CHIEKO, Ishifune, YOICHI, Maekawa, KOJI, Yasutomo, MASAHIRA, Hattori, TETSUYA, Hayashi, KENSHIRO, Oshima, KEN, Kurokawa, TADASUKE, Ooka, HIDEKI, Hirakawa, TAKEHIKO, Itoh, HARUYUKI, Nakayama-Imaohji, MINORU, Ichimura, KIKUJI, Itoh

“…Numerous microbes inhabit the mammalian intestinal track and strongly impact host physiology; however, our understanding of this ecosystem remains limited…”
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Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction by Kijima, Mika, Yamaguchi, Takeshi, Ishifune, Chieko, Maekawa, Yoichi, Koyanagi, Akemi, Yagita, Hideo, Chiba, Shigeru, Kishihara, Kenji, Shimada, Mitsuo, Yasutomo, Koji

“…Natural killer (NK) cells regulate various immune responses by exerting cytotoxic activity or secreting cytokines. The interaction of NK cells with dendritic…”
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Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model by Nishide, Shunji, Matsunaga, Shinji, Shiota, Masayuki, Yamaguchi, Takehiro, Kitajima, Shojiro, Maekawa, Yoichi, Takeda, Norihiko, Tomura, Michio, Uchida, Junji, Miura, Katsuyuki, Nakatani, Tatsuya, Tomita, Shuhei

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Manipulation of CD98 resolves type 1 diabetes in nonobese diabetic mice by Lian, Gaojian, Arimochi, Hideki, Kitamura, Akiko, Nishida, Jun, Li, Shigen, Kishihara, Kenji, Maekawa, Yoichi, Yasutomo, Koji

“…The interplay of CD4(+) and CD8(+) T cells targeting autoantigens is responsible for the progression of a number of autoimmune diseases, including type 1…”
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