Search Results - "YISHENG HE"

Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids by He, Yisheng, Zhu, Lin, Ma, Jiang, Lin, Ge

“…Pyrrolizidine alkaloids (PAs) and PA N -oxides are common phytotoxins produced by over 6000 plant species. Humans are frequently exposed to PAs via ingestion…”
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Fasting augments pyrrolizidine alkaloid-induced hepatotoxicity by Ma, Jiang, Zhang, Chunyuan, He, Yisheng, Chen, Xinmeng, Lin, Ge

“…Pyrrolizidine alkaloids (PAs) are phytotoxins widely present in various natural products and foodstuffs. The present study aims to investigate the effects of…”
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Future study for the urinary histidine adduct derived from pyrrolizidine alkaloids is warranted by Zhu, Lin, Zhang, Chunyuan, Ma, Jiang, He, Yisheng, Lin, Ge

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Clinical application of pyrrole–hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans by Ma, Jiang, Zhang, Wei, He, Yisheng, Zhu, Lin, Zhang, Chunyuan, Liu, Jia, Ye, Yang, Zhuge, Yuzheng, Lin, Ge

“…Pyrrolizidine alkaloids (PAs) are naturally occurring hepatotoxins widely present in hundreds of plant species and also known to contaminate many foodstuffs,…”
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Lung injury induced by pyrrolizidine alkaloids depends on metabolism by hepatic cytochrome P450s and blood transport of reactive metabolites by He, Yisheng, Lian, Wei, Ding, Liang, Fan, Xiaoyu, Ma, Jiang, Zhang, Qing-Yu, Ding, Xinxin, Lin, Ge

“…Pyrrolizidine alkaloids (PAs) are common phytotoxins with both hepatotoxicity and pneumotoxicity. Hepatic cytochrome P450 enzymes are known to bioactivate PAs…”
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Mutational Signature Analysis Reveals Widespread Contribution of Pyrrolizidine Alkaloid Exposure to Human Liver Cancer by He, Yisheng, Shi, Mai, Wu, Xu, Ma, Jiang, Ng, Kevin Tak‐Pan, Xia, Qingsu, Zhu, Lin, Fu, Peter Pi‐Cheng, Man, Kwan, Tsui, Stephen Kwok‐Wing, Lin, Ge

“…Background and Aims Mutational signature analyses are an effective tool in identifying cancer etiology. Humans are frequently exposed to pyrrolizidine…”
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Conservation and divergence of related neuronal lineages in the Drosophila central brain by Lee, Ying-Jou, Yang, Ching-Po, Miyares, Rosa L, Huang, Yu-Fen, He, Yisheng, Ren, Qingzhong, Chen, Hui-Min, Kawase, Takashi, Ito, Masayoshi, Otsuna, Hideo, Sugino, Ken, Aso, Yoshi, Ito, Kei, Lee, Tzumin

“…Wiring a complex brain requires many neurons with intricate cell specificity, generated by a limited number of neural stem cells. central brain lineages are a…”
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A complete developmental sequence of a Drosophila neuronal lineage as revealed by twin-spot MARCM by Yu, Hung-Hsiang, Kao, Chih-Fei, He, Yisheng, Ding, Peng, Kao, Jui-Chun, Lee, Tzumin

“…Drosophila brains contain numerous neurons that form complex circuits. These neurons are derived in stereotyped patterns from a fixed number of progenitors,…”
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Developing urinary pyrrole–amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human by Zhu, Lin, Zhang, Chunyuan, Zhang, Wei, Xia, Qingsu, Ma, Jiang, He, Xin, He, Yisheng, Fu, Peter P., Jia, Wei, Zhuge, Yuzheng, Lin, Ge

“…Pyrrolizidine alkaloids (PAs) have been found in over 6000 plants worldwide and represent the most common hepatotoxic phytotoxins. Currently, a definitive…”
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Clonal Development and Organization of the Adult Drosophila Central Brain by Yu, Hung-Hsiang, Awasaki, Takeshi, Schroeder, Mark David, Long, Fuhui, Yang, Jacob S., He, Yisheng, Ding, Peng, Kao, Jui-Chun, Wu, Gloria Yueh-Yi, Peng, Hanchuan, Myers, Gene, Lee, Tzumin

“…The insect brain can be divided into neuropils that are formed by neurites of both local and remote origin. The complexity of the interconnections obscures how…”
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A searchable image resource of Drosophila GAL4 driver expression patterns with single neuron resolution by Meissner, Geoffrey W, Nern, Aljoscha, Dorman, Zachary, DePasquale, Gina M, Forster, Kaitlyn, Gibney, Theresa, Hausenfluck, Joanna H, He, Yisheng, Iyer, Nirmala A, Jeter, Jennifer, Johnson, Lauren, Johnston, Rebecca M, Lee, Kelley, Melton, Brian, Yarbrough, Brianna, Zugates, Christopher T, Clements, Jody, Goina, Cristian, Otsuna, Hideo, Rokicki, Konrad, Svirskas, Robert R, Aso, Yoshinori, Card, Gwyneth M, Dickson, Barry J, Ehrhardt, Erica, Goldammer, Jens, Ito, Masayoshi, Kainmueller, Dagmar, Korff, Wyatt, Mais, Lisa, Minegishi, Ryo, Namiki, Shigehiro, Rubin, Gerald M, Sterne, Gabriella R, Wolff, Tanya, Malkesman, Oz

“…Precise, repeatable genetic access to specific neurons via GAL4/UAS and related methods is a key advantage of neuroscience. Neuronal targeting is typically…”
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Correlation Investigation between Pyrrole-DNA and Pyrrole-Protein Adducts in Male ICR Mice Exposed to Retrorsine, a Hepatotoxic Pyrrolizidine Alkaloid by Zhu, Lin, Xue, Junyi, He, Yisheng, Xia, Qingsu, Fu, Peter P., Lin, Ge

“…Pyrrolizidine alkaloids (PAs) have been found in over 6000 plants worldwide and represent the most common hepatotoxic phytotoxins. Catalyzed by hepatic…”
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The key role of gut–liver axis in pyrrolizidine alkaloid-induced hepatotoxicity and enterotoxicity by He, Yisheng, Ma, Jiang, Fan, Xiaoyu, Ding, Liang, Ding, Xinxin, Zhang, Qing-Yu, Lin, Ge

“…Pyrrolizidine alkaloids (PAs) are the most common phytotoxins with documented human hepatotoxicity. PAs require metabolic activation by cytochromes P450 to…”
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Liquorice Extract and 18β-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation by Wang, Zhangting, Ma, Jiang, Yao, Sheng, He, Yisheng, Miu, Kai-Kei, Xia, Qingsu, Fu, Peter P, Ye, Yang, Lin, Ge

“…Misuse of pyrrolizidine alkaloid (PA)-containing plants or consumption of PA-contaminated foodstuffs causes numerous poisoning cases in humans yearly, while…”
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Excessive Intake of Longan Arillus Alters gut Homeostasis and Aggravates Colitis in Mice by Huang, Huimin, Li, Mingxing, Wang, Yi, Wu, Xiaoxiao, Shen, Jing, Xiao, Zhangang, Zhao, Yueshui, Du, Fukuan, Chen, Yu, Wu, Zhigui, Ji, Huijiao, Zhang, Chunyuan, Li, Jing, Wen, Qinglian, Kaboli, Parham Jabbarzadeh, Cho, Chi Hin, Wang, Shengpeng, Wang, Yitao, He, Yisheng, Wu, Xu

“…Longan is the fruit of Lour. and the longan arillus has long been used in traditional Chinese medicine possessing various health benefits. However, the…”
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Diverse neuronal lineages make stereotyped contributions to the Drosophila locomotor control center, the central complex by Yang, Jacob S., Awasaki, Takeshi, Yu, Hung-Hsiang, He, Yisheng, Ding, Peng, Kao, Jui-Chun, Lee, Tzumin

“…The Drosophila central brain develops from a fixed number of neuroblasts. Each neuroblast makes a clone of neurons that exhibit common trajectories. Here we…”
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Recent advances of aggregation‐induced emission in body surface organs by Li, Hang, Zhang, Tingting, Liao, Yingying, Liu, Chutong, He, Yisheng, Wang, Yongfei, Li, Conglei, Jiang, Cheng, Li, Chenzhong, Luo, Guanghong, Xiang, Zhongyuan, Duo, Yanhong

“…The surface organs mainly comprise the superficial layers of various parts of the mammalian body, including the skin, eyes, and ears, which provide solid…”
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Making Drosophila lineage–restricted drivers via patterned recombination in neuroblasts by Awasaki, Takeshi, Kao, Chih-Fei, Lee, Ying-Jou, Yang, Ching-Po, Huang, Yaling, Pfeiffer, Barret D, Luan, Haojiang, Jing, Xiaotang, Huang, Yu-Fen, He, Yisheng, Schroeder, Mark David, Kuzin, Alexander, Brody, Thomas, Zugates, Christopher T, Odenwald, Ward F, Lee, Tzumin

“…In this Technical Report, the authors describe a new technique for the unambiguous lineage tracing of specific Drosophila neuroblasts. This methodology…”
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Hierarchical Deployment of Factors Regulating Temporal Fate in a Diverse Neuronal Lineage of the Drosophila Central Brain by Kao, Chih-Fei, Yu, Hung-Hsiang, He, Yisheng, Kao, Jui-Chun, Lee, Tzumin

“…The anterodorsal projection neuron lineage of Drosophila melanogaster produces 40 neuronal types in a stereotypic order. Here we take advantage of this…”
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Excessive consumption of the sugar rich longan fruit promoted the development of nonalcoholic fatty liver disease via mediating gut dysbiosis by Wu, Xu, Huang, Huimin, Li, Mingxing, Wang, Yi, Wu, Xiaoxiao, Wang, Qin, Shen, Jing, Xiao, Zhangang, Zhao, Yueshui, Du, Fukuan, Chen, Yu, Yang, Yifei, Zhao, Qianyun, Zeng, Jiuping, He, Yisheng, Xiao, Jianbo

“…Controversy exists as toward the association of excessive fruits intake and certain disease risks. Longan is an edible fruit rich in high levels of fructose,…”
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