Search Results - "YIM LING YIP"
-
1
Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
Published in Nature communications (07-11-2018)“…The lack of representative nasopharyngeal carcinoma (NPC) models has seriously hampered research on EBV carcinogenesis and preclinical studies in NPC. Here we…”
Get full text
Journal Article -
2
Expression of Epstein-Barr virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells
Published in Journal of medical virology (01-10-2010)“…Cell immortalization is regarded as an early and pre‐requisite step in tumor development. Defining the specific genetic events involved in cell immortalization…”
Get full text
Journal Article -
3
Etiological factors of nasopharyngeal carcinoma
Published in Oral oncology (01-05-2014)“…Summary Nasopharyngeal carcinoma (NPC) is a common disease among southern Chinese. The major etiological factors proposed for NPC pathogenesis include genetic…”
Get full text
Journal Article -
4
Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression
Published in Nature communications (10-02-2017)“…Local interactions between cancer cells and stroma can produce systemic effects on distant organs to govern cancer progression. Here we show that IGF2 secreted…”
Get full text
Journal Article -
5
Establishment of a nasopharyngeal carcinoma cell line capable of undergoing lytic Epstein–Barr virus reactivation
Published in Laboratory investigation (01-08-2018)“…Epstein–Barr virus (EBV) infects more than 90% of the adult human population. Undifferentiated nasopharyngeal carcinoma (NPC) is common in Southeast Asia, with…”
Get full text
Journal Article -
6
Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cells
Published in Proceedings of the National Academy of Sciences - PNAS (11-12-2012)“…Undifferentiated nasopharyngeal carcinomas (NPCs) are commonly present with latent EBV infection. However, events regulating EBV infection at early stages of…”
Get full text
Journal Article -
7
Dual‐Targeting Peptide‐Guided Approach for Precision Delivery and Cancer Monitoring by Using a Safe Upconversion Nanoplatform
Published in Advanced science (01-03-2021)“…Using Epstein‐Barr virus (EBV)‐induced cancer cells and HeLa cells as a comparative study model, a novel and safe dual‐EBV‐oncoproteins‐targeting pH‐responsive…”
Get full text
Journal Article -
8
Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts
Published in BMC cancer (31-12-2013)“…Cortidis rhizoma (Huanglian) and its major therapeutic component, berberine, have drawn extensive attention in recent years for their anti-cancer properties…”
Get full text
Journal Article -
9
Enhanced IL-6/IL-6R signaling promotes growth and malignant properties in EBV-infected premalignant and cancerous nasopharyngeal epithelial cells
Published in PloS one (01-05-2013)“…Nasopharyngeal carcinoma (NPC) is etiologically associated with Epstein-Barr virus (EBV) infection. However, the exact role of EBV in NPC pathogenesis remains…”
Get full text
Journal Article -
10
Defining early events of Epstein-Barr virus (EBV) infection in immortalized nasopharyngeal epithelial cells using cell-free EBV infection
Published in Journal of general virology (01-06-2019)“…Epstein-Barr virus (EBV) infection is strongly associated with nasopharyngeal carcinoma, a common cancer in Southeast Asia and certain regions of Africa…”
Get full text
Journal Article -
11
Epstein‐Barr virus infection in immortalized nasopharyngeal epithelial cells: Regulation of infection and phenotypic characterization
Published in International journal of cancer (01-10-2010)“…Epstein‐Barr virus (EBV) infection has been postulated to be an early event involved in the pathogenesis of nasopharyngeal carcinomas (NPC). The lack of…”
Get full text
Journal Article -
12
Efficient immortalization of primary nasopharyngeal epithelial cells for EBV infection study
Published in PloS one (22-10-2013)“…Nasopharyngeal carcinoma (NPC) is common among southern Chinese including the ethnic Cantonese population living in Hong Kong. Epstein-Barr virus (EBV)…”
Get full text
Journal Article -
13
Epstein-Barr virus-encoded latent membrane protein 1 impairs G2 checkpoint in human nasopharyngeal epithelial cells through defective Chk1 activation
Published in PloS one (25-06-2012)“…Nasopharyngeal carcinoma (NPC) is a common cancer in Southeast Asia, particularly in southern regions of China. EBV infection is closely associated with NPC…”
Get full text
Journal Article -
14
Id1 interacts and stabilizes the Epstein-Barr virus latent membrane protein 1 (LMP1) in nasopharyngeal epithelial cells
Published in PloS one (20-06-2011)“…The EBV-encoded latent membrane protein 1 (LMP1) functions as a constitutive active form of tumor necrosis factor receptor (TNFR) and activates multiple…”
Get full text
Journal Article -
15
Epstein-Barr virus infection and persistence in nasopharyngeal epithelial cells
Published in Ai zheng (01-11-2014)“…Epstein-Barr virus (EBV) infection is closely associated with undifferentiated nasopharyngeal carcinoma (NPC), strongly implicating a role for EBV in NPC…”
Get full text
Journal Article -
16
Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling Pathways
Published in Journal of virology (15-03-2017)“…Accumulating evidence indicates that oncogenic viral protein plays a crucial role in activating aerobic glycolysis during tumorigenesis, but the underlying…”
Get full text
Journal Article -
17
mTORC2-mediated PDHE1α nuclear translocation links EBV-LMP1 reprogrammed glucose metabolism to cancer metastasis in nasopharyngeal carcinoma
Published in Oncogene (13-06-2019)“…EBV infection of preinvasive nasopharyngeal epithelium is believed to be an initiation step during pathogenesis of nasopharyngeal carcinoma (NPC), but the…”
Get full text
Journal Article -
18
Significance of NF‐κB activation in immortalization of nasopharyngeal epithelial cells
Published in International journal of cancer (01-03-2016)“…NF‐κB is a key regulator of inflammatory response and is frequently activated in human cancer including the undifferentiated nasopharyngeal carcinoma (NPC),…”
Get full text
Journal Article -
19
Abstract 56: Establishment and characterization of new tumor xenografts and cancer cell lines from EBV positive nasopharyngeal carcinoma
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Nasopharyngeal carcinoma (NPC) is rare worldwide but common in southern China, including Hong Kong. The endemic NPC among southern Chinese is typically…”
Get full text
Journal Article -
20
Loss of ΔNp63α promotes mitotic exit in epithelial cells
Published in FEBS letters (01-06-2017)Get full text
Journal Article