Search Results - "YI, Poravuth"
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A Major Genome Region Underlying Artemisinin Resistance in Malaria
Published in Science (American Association for the Advancement of Science) (06-04-2012)“…Evolving resistance to arte misi ni n-based compounds threatens to derail attempts to control malaria. Resistance has been confirmed in western Cambodia and…”
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Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription
Published in BMC genomics (03-08-2011)“…Artemisinin resistance in Plasmodium falciparum malaria has emerged in Western Cambodia. This is a major threat to global plans to control and eliminate…”
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3
High Heritability of Malaria Parasite Clearance Rate Indicates a Genetic Basis for Artemisinin Resistance in Western Cambodia
Published in The Journal of infectious diseases (01-05-2010)“…In western Cambodia, malaria parasites clear slowly from the blood after treatment with artemisinin derivatives, but it is unclear whether this results from…”
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Exploring the Contribution of Candidate Genes to Artemisinin Resistance in Plasmodium falciparum
Published in Antimicrobial Agents and Chemotherapy (01-07-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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5
Pyronaridine–Artesunate versus Mefloquine plus Artesunate for Malaria
Published in The New England journal of medicine (05-04-2012)“…New therapies to treat malaria are needed. In this report, in which the authors studied 1271 patients from Asia and Africa, pyronaridine–artesunate was found…”
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Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial
Published in PloS one (18-01-2011)“…New antimalarials are needed for P. vivax and P. falciparum malaria. This study compared the efficacy and safety of pyronaridine-artesunate with that of…”
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Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia
Published in Malaria journal (12-01-2009)“…The combination of artesunate and mefloquine was introduced as the national first-line treatment for Plasmodium falciparum malaria in Cambodia in 2000…”
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Decreased In Vitro Susceptibility of Plasmodium falciparum Isolates to Artesunate, Mefloquine, Chloroquine, and Quinine in Cambodia from 2001 to 2007
Published in Antimicrobial Agents and Chemotherapy (01-05-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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9
Efficacy and Safety of Dihydroartemisinin-Piperaquine (Artekin) in Cambodian Children and Adults with Uncomplicated Falciparum Malaria
Published in Clinical infectious diseases (15-12-2002)“…The safety and efficacy of a novel combination of dihydroartemisinin (DHA) and piperaquine, Artekin (Holleykin Pharmaceuticals), were assessed in 106 patients…”
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Artemisinin Resistance in Plasmodium falciparum Malaria
Published in The New England journal of medicine (30-07-2009)“…Artemisinin therapy is a first-line approach to malaria treatment in many parts of the world. Resistance to this class of agents is an emerging threat to…”
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Laboratory Detection of Artemisinin-Resistant Plasmodium falciparum
Published in Antimicrobial agents and chemotherapy (01-06-2014)“…Conventional 48-h in vitro susceptibility tests have low sensitivity in identifying artemisinin-resistant Plasmodium falciparum, defined phenotypically by low…”
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Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria
Published in Clinical infectious diseases (01-03-2013)“…The emergence of Plasmodium falciparum resistance to artemisinins on the Cambodian and Myanmar-Thai borders poses severe threats to malaria control. We…”
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13
Efficacy of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia
Published in Tropical medicine & international health (01-12-2006)“…Summary Objective To determine the efficacy of artemether–lumefantrine malaria treatment, as an alternative to artesunate + mefloquine, which is becoming…”
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Surveillance of the efficacy of artesunate and mefloquine combination for the treatment of uncomplicated falciparum malaria in Cambodia
Published in Tropical medicine & international health (01-09-2006)“…Summary Artesunate and mefloquine combination treatment has been used since 2000 in Cambodia as the first‐line drug for the treatment of uncomplicated…”
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In vitro monitoring of Plasmodium falciparum susceptibility to artesunate, mefloquine, quinine and chloroquine in Cambodia: 2001–2002
Published in Acta tropica (2005)“…We used a classical isotopic microtest to assess the in vitro sensitivity of 352 Plasmodium falciparum isolates collected in Cambodia in 2001 and 2002 to…”
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Genetic variation of the dihydrofolate reductase gene in Plasmodium vivax in Snoul, northeastern Cambodia
Published in Acta tropica (01-09-2004)“…In Plasmodium vivax, pyrimethamine resistance is associated with amino acid substitutions Ser117Asn and Ser58Arg in dihydrofolate reductase (DHFR), which…”
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Pfmdr1 and in vivo resistance to artesunate-mefloquine in falciparum malaria on the Cambodian-Thai border
Published in The American journal of tropical medicine and hygiene (01-04-2007)“…Artemisinin combination therapies (ACTs) have recently been adopted as first-line therapy for Plasmodium falciparum infections in most malaria-endemic…”
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