Search Results - "YEN, ALBERT A"
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Machine Learning Outperforms ACC / AHA CVD Risk Calculator in MESA
Published in Journal of the American Heart Association (20-11-2018)“…Background Studies have demonstrated that the current US guidelines based on American College of Cardiology/American Heart Association (ACC/AHA) Pooled Cohort…”
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Wild-Type Microglia Extend Survival in PU.1 Knockout Mice with Familial Amyotrophic Lateral Sclerosis
Published in Proceedings of the National Academy of Sciences - PNAS (24-10-2006)“…The most common inherited form of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting adult motoneurons, is caused by dominant mutations…”
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High Frequency of Microvascular Dysfunction in US Outpatient Clinics: A Sign of High Residual Risk? Data from 7,105 Patients
Published in International journal of vascular medicine (2022)“…Previous studies have linked peripheral microvascular dysfunction measured by arterial tonometry to high residual risk in on-statin patients. Digital thermal…”
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4
Amyotrophic lateral sclerosis : early predictors of prolonged survival
Published in Journal of neurology (01-11-2006)“…In order to define the predictors of prolonged survival available at the time of first examination we performed a historical cohort study of amyotrophis…”
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New Indices of Endothelial Function Measured by Digital Thermal Monitoring of Vascular Reactivity: Data from 6084 Patients Registry
Published in International Journal of Vascular Medicine (01-01-2016)“…Background. Endothelial function is viewed as a barometer of cardiovascular health and plays a central role in vascular reactivity. Several studies showed…”
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Activated Microglia Initiate Motor Neuron Injury by a Nitric Oxide and Glutamate-Mediated Mechanism
Published in Journal of neuropathology and experimental neurology (01-09-2004)“…Recent studies suggest that motor neuron (MN) death may be non-cell autonomous, with cell injury mediated by interactions involving non-neuronal cells, such as…”
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7
Predictability of disease progression in amyotrophic lateral sclerosis
Published in Muscle & nerve (01-12-2006)“…The aim of this study was to determine the predictors of disease progression in a group of 832 patients with the diagnosis of definite or probable amyotrophic…”
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Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia
Published in Journal of neurochemistry (01-09-2007)“…Recent studies suggest that microglia over-expressing mutant human superoxide dismutase (mSOD1(G93A)) may contribute to motoneuron death in a transgenic mouse…”
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Mutant SOD1G⁹³A microglia are more neurotoxic relative to wild-type microglia
Published in Journal of neurochemistry (01-09-2007)“…Recent studies suggest that microglia over-expressing mutant human superoxide dismutase (mSOD1G⁹³A) may contribute to motoneuron death in a transgenic mouse…”
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10
Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson’s disease
Published in Biochemical and biophysical research communications (21-04-2006)“…We have used quantitative 2D gel electrophoresis to analyze serum proteins from 422 patients with neurodegenerative diseases and normal individuals in an…”
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Oxidative Stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis
Published in Current opinion in rheumatology (01-11-2003)“…PURPOSE OF REVIEWAmyotrophic lateral sclerosis, or Lou Gehrig disease, is a progressive neurodegenerative disease of adult onset characterized by a loss of…”
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Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing?
Published in Archives of neurology (Chicago) (01-08-2006)“…In recent years, considerable effort has been made to improve the treatment of patients with amyotrophic lateral sclerosis (ALS). However, despite the…”
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13
Digital thermal monitoring (DTM) of vascular reactivity closely correlates with doppler flow velocity
Published in 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (01-01-2009)“…The noninvasive measurement of peripheral vascular reactivity, as an indicator of vascular function, provides a valuable tool for cardiovascular screening of…”
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Mutant SOD1 super(G93A) microglia are more neurotoxic relative to wild-type microglia
Published in Journal of neurochemistry (01-09-2007)“…Recent studies suggest that microglia over-expressing mutant human superoxide dismutase (mSOD1 super(G93A)) may contribute to motoneuron death in a transgenic…”
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15
Mutant SOD1 G93A microglia are more neurotoxic relative to wild‐type microglia
Published in Journal of neurochemistry (01-09-2007)“…Recent studies suggest that microglia over‐expressing mutant human superoxide dismutase (mSOD1 G93A ) may contribute to motoneuron death in a transgenic mouse…”
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Journal Article