Search Results - "YEM, A"

High proprioceptive acuity in slow and fast hand movements by Yoss, Abby L., Zuck, Bennett I., Yem, Joshua A., Darling, Warren G.

“…We can accurately reach to touch our index fingertip to various points on the body without vision. Awareness of location/motion of the index fingertip and…”
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Crystal Structure of the Catalytic Subunit of Cdc25B Required for G/M Phase Transition of the Cell Cycle by Reynolds, R A, Yem, A W, Wolfe, CL, jr, Deibel, Chidester, C G, Watenpaugh, K D

“…Cdc25B is a dual specificity phosphatase involved in the control of cyclin-dependent kinases and the progression of cells through the cell cycle. A series of…”
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The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13 by A W Yem, A G Tomasselli, R L Heinrikson, H Zurcher-Neely, V A Ruff, R A Johnson, M R Deibel, Jr

“…Extracts from human Jurkat cells or from calf thymus contain a 60-kDa protein that is bound to immobilized FK506. As expected, the NH2-terminal sequences of…”
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Tissue distribution and cellular localization of hsp56, an FK506-binding protein. Characterization using a highly specific polyclonal antibody by Ruff, V.A., Yem, A.W., Munns, P.L., Adams, L.D., Reardon, I.M., Deibel, M.R., Leach, K.L.

“…Heat shock protein 56 (hsp56) has been shown to be involved in two cellular pathways, as an immunophilin for FK506 and as a component of steroid receptor…”
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Crystal Structure of Type II Peptide Deformylase from Staphylococcus aureus by Baldwin, Eric T, Harris, Melissa S, Yem, Anthony W, Wolfe, Cindy L, Vosters, Anne F, Curry, Kimberly A, Murray, Robert W, Bock, Jeffrey H, Marshall, Vincent P, Cialdella, Joyce I, Merchant, Mahesh H, Choi, Gil, Deibel, Jr, Martin R

“…The first crystal structure of Class II peptide deformylase has been determined. The enzyme from Staphylococcus aureus has been overexpressed and purified in…”
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Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus by TOMASSELLI, A. G, HUI, J. O, ADAMS, L, CHOSAY, J, LOWERY, D, GREENBERG, B, YEM, A, DEIBEL, M. R, ZÜRCHER-NEELY, H, HEINRIKSON, R. L

“…We show here for the first time that actin, troponin C, Alzheimer amyloid precursor protein (AAP), and pro-interleukin 1 beta (pro-IL-1 beta), are substrates…”
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Backbone (1H, 15N, 13C) resonance assignments of a 21 kDa construct of S. aureus peptide deformylase by Scahill, T A, Kloosterman, D A, Cialdella, J I, Deibel, Jr, M R, Marshall, V P, Yem, A W

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The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor by Czar, M J, Owens-Grillo, J K, Yem, A W, Leach, K L, Deibel, Jr, M R, Welsh, M J, Pratt, W B

“…In their unliganded state, mouse glucocorticoid receptors (GR) that are overexpressed in the WCL2 line of Chinese hamster ovary cells are distributed in a…”
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Immobilization of a Novel Antibacterial Agent on Solid Phase and Subsequent Isolation of EF-Tu by Deibel, Martin R, Bodnar, Alice L, Yem, Anthony W, Wolfe, Cindy L, Heckaman, Charlotte L, Bohanon, Michael J, Mathews, W. Rodney, Sweeney, Michael T, Zurenko, Gary E, Marotti, Keith R, Boyle, Timothy P, Thorarensen, Atli

“…Screening of our compound collection identified PNU-92560, a 2-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxamide, as a novel antibacterial agent. Extensive…”
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Site-specific chemical modification of interleukin-1 beta by acrylodan at cysteine 8 and lysine 103 by A W Yem, D E Epps, W R Mathews, D M Guido, K A Richard, N D Staite, M R Deibel, Jr

“…Acrylodan, which normally modifies cysteine residues, was employed to derivatize recombinant interleukin-1 beta (rIL-1 beta) under native conditions, using a…”
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Identification of novel potent hydroxamic acid inhibitors of peptidyl deformylase and the importance of the hydroxamic acid functionality on inhibition by Thorarensen, Atli, Douglas, Jr, Martin R., Rohrer, Douglas C., Vosters, Anne F., Yem, Anthony W., Marshall, Vincent D., Lynn, Janet C., Bohanon, Michael J., Tomich, Paul K., Zurenko, Gary E., Sweeney, Michael T., Jensen, Randy M., Nielsen, James W., Seest, Eric P., Dolak, Lester A.

“…Peptidyl deformylase (PDF) is a metallo protease that catalyzes the removal of a formyl group from the N-termini of prokaryotic prepared polypeptides, an…”
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Biotinylation of reactive amino groups in native recombinant human interleukin-1β by Yem, A W, Zurcher-Neely, H A, Richard, K A, Staite, N D, Heinrikson, R L, Deibel, M R

“…Recombinant human interleukin-1β (rIL-1β) was chemically modified by a 10-fold molar excess (reagent:protein) of sulfosuccinimidyl 6-(biotinamido) hexanoate…”
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Spectral characterization of environment-sensitive adducts of interleukin-1 beta by D E Epps, A W Yem, J F Fisher, J E McGee, J W Paslay, M R Deibel, Jr

“…We have determined the fluorescence properties of two covalently attached acrylodan derivatives of recombinant human interleukin-1 beta, namely the Cys-8 and…”
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Modulation of Ia-like antigen expression and antigen-presenting activity of human monocytes by endotoxin and zymosan A by Yem, AW, Parmely, MJ

“…The environmental agents E. coli endotoxin and zymosan A modulated antigen-specific T cell proliferation in vitro, assessed by 3H-TdR uptake. In the continual…”
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Secondary structure and topology of interleukin-1 receptor antagonist protein determined by heteronuclear three-dimensional NMR spectroscopy by Stockman, Brian J, Scahill, Terrence A, Roy, Melinda, Ulrich, Eldon L, Strakalaitis, Nancy A, Brunner, David P, Yem, Anthony W, Deibel, Martin R

“…Interleukin-1 (IL-1) proteins, such as IL-1 beta, play a key role in immune and inflammatory responses. Interaction of these cytokines with the IL-1 receptor…”
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Crystallization of purified recombinant human interleukin-1 beta by Carter, D B, Curry, K A, Tomich, C S, Yem, A W, Deibel, M R, Tracey, D E, Paslay, J W, Carter, J B, Theriault, N Y, Harris, P K

“…The gene for human interleukin-1 beta was cloned from SK-hep-1 hepatoma cellular RNA and expressed at high levels in Escherichia coli both as the naturally…”
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Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle by Reynolds, R A, Yem, A W, Wolfe, C L, Deibel, Jr, M R, Chidester, C G, Watenpaugh, K D

“…Cdc25B is a dual specificity phosphatase involved in the control of cyclin-dependent kinases and the progression of cells through the cell cycle. A series of…”
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On-resin biotinylation of chemically synthesized proteins for one-step purification by Lobl, T J, Deibel, Jr, M R, Yem, A W

“…A general, convenient, one-step purification procedure for chemically synthesized proteins present in low yields using on-resin biotinylation is reported. The…”
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Identification of a C-terminal cdc25 sequence required for promotion of germinal vesicle breakdown by Powers, E A, Thompson, D P, Garner-Hamrick, P A, He, W, Yem, A W, Bannow, C A, Staples, D J, Waszak, G A, Smith, C W, Deibel, Jr, M R, Fisher, C

“…Glutathione S-transferase (GST)-cdc25B(31-566) induced germinal vesicle breakdown (GVBD) when microinjected into Xenopus oocytes. Purified, N-terminally…”
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Solution structure of human interleukin-1 receptor antagonist protein by Stockman, Brian J., Scahill, Terrence A., Strakalaitis, Nancy A., Brunner, David P., Yem, Anthony W., Deibel, Martin R.

“…Interleukin-1 receptor antagonist protein (IRAP) is a naturally occurring inhibitor of the interleukin-1 receptor. In contrast to IL-1β IRAP binds to the IL-1…”
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