Epidemiology of Invasive Haemophilus influenzae Type b Infections among Children in Greece before the Introduction of Immunization

We prospectively examined the epidemiology of invasive Haemophilus influenzae type b (Hib) infections among children under 5 y of age in the Greater Athens area before the introduction of immunization. The annual incidence of systemic Hib infections was 12/100,000. Meningitis was the most common cli...

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Bibliographic Details
Published in:	Scandinavian journal of infectious diseases Vol. 30; no. 2; pp. 165 - 168
Main Authors:	TSOLIA, M. N, THEODORIDOU, M. N, MOSTROU, G. J, PARASKAKI, I. I, PANGALI, A. M, YELESME, A. S, KALAMBALIKIS, P. K, GAVIOTAKI, A. E, ZOUMBOULAKIS, D. J, SINANIOTIS, C. A
Format:	Journal Article
Language:	English
Published:	Basingstoke Informa UK Ltd 1998 Taylor & Francis
Subjects:	Bacteremia - diagnosis Bacteremia - epidemiology Bacterial diseases Bacterial diseases of the nervous system. Bacterial myositis Biological and medical sciences Child, Preschool Cohort Studies Female Greece - epidemiology Haemophilus Infections - diagnosis Haemophilus Infections - epidemiology Haemophilus influenzae Haemophilus influenzae type b - isolation & purification Human bacterial diseases Humans Immunization - trends Incidence Infant Infectious diseases Male Medical sciences Meningitis, Haemophilus - diagnosis Meningitis, Haemophilus - epidemiology Prospective Studies Risk Factors Sex Distribution Time Factors Greece Europe Human Nervous system diseases Clinical form Epidemiology Haemophilus influenzae Incidence Infection Pasteurellaceae Symptomatology Central nervous system disease Bacteriosis Bacteria Meningitis Disseminated Child Age
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Summary:	We prospectively examined the epidemiology of invasive Haemophilus influenzae type b (Hib) infections among children under 5 y of age in the Greater Athens area before the introduction of immunization. The annual incidence of systemic Hib infections was 12/100,000. Meningitis was the most common clinical entity and accounted for 69% of the cases. In the prevaccine era, the incidence of systemic Hib disease, particularly that of meningitis, was much lower in Greece compared to rates reported from Northern and Central Europe.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	0036-5548 1651-1980
DOI:	10.1080/003655498750003564